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Molecular pharmaceutics, ISSN 1543-8384, 03/2019, Volume 16, Issue 3, pp. 1282 - 1293
blood-brain barrier | P-glycoprotein | tyrosine kinase inhibitors | breast cancer resistance protein | C]erlotinib | [ | positron emission tomography | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Capillary Permeability - physiology | Quinolines - blood | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Cyclosporine - pharmacology | Quinolines - administration & dosage | Quinolines - pharmacology | Brain - metabolism | Cyclosporine - blood | Tissue Distribution | Radiopharmaceuticals - metabolism | Drug Interactions | Female | Models, Animal | ATP Binding Cassette Transporter, Subfamily G, Member 2 - antagonists & inhibitors | Cyclosporine - metabolism | Radiopharmaceuticals - pharmacology | Erlotinib Hydrochloride - administration & dosage | Solubility | Positron-Emission Tomography - methods | Protein Kinase Inhibitors - blood | Blood-Brain Barrier - metabolism | Erlotinib Hydrochloride - blood | Radiopharmaceuticals - blood | Quinolines - metabolism | Radiopharmaceuticals - administration & dosage | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Protein Kinase Inhibitors - administration & dosage | Animals | Erlotinib Hydrochloride - pharmacology | Cyclosporine - administration & dosage | Erlotinib Hydrochloride - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Protein Kinase Inhibitors - metabolism | Index Medicus
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2010, Volume 376, Issue 9749, pp. 1320 - 1328
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cardiology. Vascular system | Heart | General aspects | Biological and medical sciences | Myocarditis. Cardiomyopathies | Medical sciences | Coronary heart disease | Ticlopidine - therapeutic use | Cardiovascular Diseases - prevention & control | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Male | Adenosine - adverse effects | Adenosine - therapeutic use | Ticlopidine - adverse effects | Female | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Cardiovascular Diseases - etiology | Pharmacogenetics | Genotype | Ticlopidine - analogs & derivatives | Randomized Controlled Trials as Topic | Acute Coronary Syndrome - drug therapy | Phenotype | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Cytochrome P-450 CYP2C19 | Adenosine - analogs & derivatives | ATP Binding Cassette Transporter, Sub-Family B | Aged | Polymorphism, Single Nucleotide | Acute Coronary Syndrome - genetics | Care and treatment | Patient outcomes | Physiological aspects | Clopidogrel | Dosage and administration | Single nucleotide polymorphisms | Health aspects | Studies | Heart attacks | Statistical analysis | Metabolites | Genetics | Drug therapy | Gene expression | Acute coronary syndromes | Myocardial infarction | Stroke | Single-nucleotide polymorphism | Arteries | Bleeding | Index Medicus | Abridged Index Medicus
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2010, Volume 376, Issue 9749, pp. 1312 - 1319
Journal Article
International journal of cancer, ISSN 0020-7136, 2020, Volume 146, Issue 6, pp. 1631 - 1642
P-glycoprotein | brain accumulation | Oatp1a/1b | intestinal disposition | cytochrome P450-3A | oral availability | galunisertib | P‐glycoprotein | cytochrome P450‐3A | Life Sciences & Biomedicine | Oncology | Science & Technology | Quinolines - blood | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Organic Anion Transporters - metabolism | Quinolines - pharmacology | Brain - metabolism | Quinolines - pharmacokinetics | Tissue Distribution | Pyrazoles - blood | Madin Darby Canine Kidney Cells | Female | Pyrazoles - pharmacokinetics | ATP Binding Cassette Transporter, Subfamily G, Member 2 - antagonists & inhibitors | Pyrazoles - pharmacology | Tetrahydroisoquinolines - pharmacology | ATP Binding Cassette Transporter, Subfamily B - metabolism | Brain - drug effects | Animals | Signal Transduction - drug effects | ATP Binding Cassette Transporter, Subfamily B - antagonists & inhibitors | Cytochrome P-450 CYP3A - metabolism | Acridines - pharmacology | Herb-Drug Interactions | Dogs | Mice | Transforming Growth Factor beta - metabolism | Brain | Efflux | Animal models | Toxicity | Transforming growth factor-b | Glioblastoma | Oral administration | Clinical trials | Hepatocellular carcinoma | Pharmacology | Breast cancer | Glycoproteins | Accumulation | MDR1 protein | Signal transduction | Inhibitors | Intestine | Pharmacokinetics | Growth factors | Genetic modification | Acute toxicity | Index Medicus
Journal Article
Glia, ISSN 0894-1491, 08/2016, Volume 64, Issue 8, pp. 1298 - 1313
Journal Article