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PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, p. e98882
Background: Multidrug resistance (MDR) is one of the major reasons chemotherapy-based treatments fail. Hypoxia is generally associated with tumor... 
CHEMOSENSITIVITY | IN-VITRO | P-GP | HYPOXIA-INDUCIBLE-FACTOR-1-ALPHA | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | GASTRIC-CANCER | MULTIDISCIPLINARY SCIENCES | MDR1 GENE | CHEMORESISTANCE | DRUG-RESISTANCE | CHEMOTHERAPY | Promoter Regions, Genetic | RNA, Small Interfering - genetics | Colonic Neoplasms - genetics | Apoptosis - drug effects | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Humans | RNA, Messenger - genetics | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | Colonic Neoplasms - metabolism | Hypoxia - metabolism | Drug Resistance, Neoplasm - genetics | Hypoxia - genetics | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Cell Line, Tumor | Protein Binding | Transcription, Genetic | Antineoplastic Agents - pharmacology | ATP Binding Cassette Transporter, Sub-Family B - genetics | Drugs | Flow cytometry | Chromatin | Hypoxia-inducible factor 1 | Immunoprecipitation | Colorectal cancer | Chemoresistance | Reversing | Oncology | mRNA | Kinases | Drug resistance | Experiments | Cancer therapies | Proteins | MDR1 protein | Colon cancer | Inhibition | Colon | P-Glycoprotein | Hypoxia-inducible factors | Sensitivity analysis | Multidrug resistance | Glycoprotein | Breast cancer | Gene expression | Spheroids | Cytometry | Chemotherapy | Sensitivity | Molecular modelling | Hypoxia | Transporter | Apoptosis | Tumors | Cancer
Journal Article
The FEBS Journal, ISSN 1742-464X, 02/2009, Volume 276, Issue 3, pp. 685 - 694
Cellular prion protein (PrPC), a glycosyl‐phosphatidylinositol‐anchored membrane protein with unclear physiological function, was previous found to be... 
drug resistance | gastric cancer | P‐gp | PI3K/Akt | prion protein | MDR-1 | P-gp | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | Akt | MRP-1 | P-GLYCOPROTEIN | OVEREXPRESSION | PI3K | PATHWAY | BIOLOGY | MULTIDRUG-RESISTANCE | EXPRESSION | Biochemistry | Cellular biology | Drug resistance | Prions | Gastroenterology | Cancer
Journal Article
by Xia, MM and Fang, YJ and Cao, WW and Liang, FQ and Pan, SY and Xu, XY
MOLECULES, ISSN 1420-3049, 05/2019, Volume 24, Issue 9, p. 1661
P-glycoprotein (P-gp) serves as a therapeutic target for the development of inhibitors to overcome multidrug resistance (MDR) in cancer cells. In order to... 
P-gp | BIOCHEMISTRY & MOLECULAR BIOLOGY | 3D-QSAR | inhibitory activity | CHEMISTRY, MULTIDISCIPLINARY | REVERSAL | VINCRISTINE RESISTANCE | QUERCETIN | IN-VITRO | QSAR | ABSORPTION | flavonoids | MULTIDRUG-RESISTANCE | DRUG TRANSPORT | EXPRESSION | MODULATION
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 05/2017, Volume 118, Issue 5, pp. 1239 - 1248
Journal Article
Current Drug Metabolism, ISSN 1389-2002, 10/2011, Volume 12, Issue 8, pp. 722 - 731
Journal Article
Molecules, ISSN 1420-3049, 06/2017, Volume 22, Issue 6, p. 871
Multidrug resistance (MDR) is regarded as one of the bottlenecks of successful clinical treatment for numerous chemotherapeutic agents. Multiple key regulators... 
P-glycoprotein (P-gp); multi drug resistance (MDR); ABC transporters; P-gp inhibitors; chemotherapy; xenobiotics | MEDIATED MULTIDRUG-RESISTANCE | EFFLUX PUMP INHIBITORS | xenobiotics | BIOCHEMISTRY & MOLECULAR BIOLOGY | multi drug resistance (MDR) | chemotherapy | BLOOD-BRAIN-BARRIER | CHEMISTRY, MULTIDISCIPLINARY | P-glycoprotein (P-gp) | RATS POSSIBLE ROLE | IN-VITRO | GRAPEFRUIT JUICE | MDR1 GENE-EXPRESSION | ABC transporters | STAPHYLOCOCCUS-AUREUS | GLUTATHIONE-S-TRANSFERASE | BISBENZYLISOQUINOLINE ALKALOIDS | P-gp inhibitors | Gene Expression | Drug Resistance, Multiple | Humans | Models, Molecular | Biological Products - pharmacology | Structure-Activity Relationship | ATP Binding Cassette Transporter, Sub-Family B - chemistry | Drug Discovery | Protein Transport | Biological Products - chemistry | Drug Resistance, Neoplasm - genetics | Animals | Models, Biological | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Protein Binding | Antineoplastic Agents - pharmacology | Molecular Structure | ATP Binding Cassette Transporter, Sub-Family B - antagonists & inhibitors | ATP Binding Cassette Transporter, Sub-Family B - genetics | Drug Resistance, Neoplasm - drug effects | Heart | Brain | Regulators | Adrenal glands | Toxicity | Membrane permeability | Drug development | Small intestine | Proteins | Constituents | Blood-brain barrier | Biocompatibility | Adrenal gland | Colon | Inhibition | Xenobiotics | Protein transport | Pancreas | P-Glycoprotein | Deposition | Spleen | Accretion | Kidneys | Cardiac muscle | Ducts | Multidrug resistance | Glycoprotein | Muscles | Tubules | Glycoproteins | Biological activity | Endothelial cells | Skeletal muscle | Bile duct | Membrane proteins | Mode of action | Chemotherapy | Overexpression | Inhibitors | Lungs | Natural products | Coupled modes | Intracellular | Drug discovery | ATP
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 11/2014, Volume 88, Issue 3, pp. 759 - 767
Journal Article