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Nuclear Medicine and Biology, ISSN 0969-8051, 2009, Volume 36, Issue 3, pp. 239 - 246
Journal Article
FEBS Letters, ISSN 0014-5793, 2006, Volume 580, Issue 4, pp. 1103 - 1111
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2015, Volume 467, Issue 1, pp. 127 - 139
ATP-binding cassette, subfamily B (ABCB) 6 is a homodimeric ATP-binding cassette (ABC) transporter present in the plasma membrane and in the intracellular... 
ATP-binding cassette (ABC) transporter | Trafficking | Adenosine 5′-triphosphatase (ATPase) | Lysosome | ATP-binding cassette | Transmembrane domain | Subfamily B (ABCB) 6 | adenosine 5 '-triphosphatase (ATPase) | B6 ABCB6 | MEMBRANE | ATPASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CONDUCTANCE REGULATOR | INSECT CELLS | P-GLYCOPROTEIN | BINDING CASSETTE TRANSPORTER | MHC CLASS-I | subfamily B (ABCB) 6 | transmembrane domain | MUTATIONS | MULTIDRUG-RESISTANCE | lysosome | trafficking | Humans | Recombinant Fusion Proteins - metabolism | ATP-Binding Cassette Transporters - chemistry | Endocytosis | Lysosomes - metabolism | ATP-Binding Cassette Transporters - genetics | Adenosine Triphosphate - metabolism | ATP-Binding Cassette Transporters - metabolism | Cell Membrane - metabolism | Dimerization | Peptide Fragments - genetics | Protein Structure, Tertiary | Microscopy, Electron, Transmission | Peptide Fragments - metabolism | Multivesicular Bodies - ultrastructure | Mutant Proteins - metabolism | Cell Membrane - ultrastructure | Recombinant Fusion Proteins - chemistry | Protein Folding | Protein Sorting Signals | Protein Transport | Hydrolysis | Lysosomes - ultrastructure | Peptide Fragments - chemistry | Mutant Proteins - chemistry | K562 Cells | Multivesicular Bodies - metabolism | HeLa Cells | Amino Acid Substitution | Lan, Langereis | P-gp, P-glycoprotein | NP-40, nonyl phenoxypolyethoxylethanol-40 | PAG, Protein A–gold | TfR, transferrin receptor | TMD0, N-terminal transmembrane domain | ABC, ATP-binding cassette | HA, human influenza haemagglutinin | MRP, multidrug resistance-associated protein | NBD, nucleotide-binding domain | HRP, horseradish peroxidase | TMD, transmembrane domain | RT, room temperature | NEM, N-ethylmaleimide | NA, numerical aperture | adenosine 5′-triphosphatase (ATPase) | PNGase-F, peptide N-glycosidase F | MDR, multidrug resistance protein | DPBS, Dulbecco’s modified phosphate-buffered saline | PFA, paraformaldehyde
Journal Article
Molecular Imaging and Biology, ISSN 1536-1632, 2/2011, Volume 13, Issue 1, pp. 152 - 160
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 05/2013, Volume 10, Issue 5, pp. 1566 - 1580
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 02/2018, Volume 58, Issue 2, pp. 202 - 211
Rolapitant is a selective and long‐acting neurokinin‐1 receptor antagonist approved in an oral formulation in combination with other antiemetic agents for the... 
neurokinin‐1 (NK‐1) | drug‐drug interactions | P‐glycoprotein (P‐gp) | breast cancer resistance protein (BCRP) | antiemetics | chemotherapy‐induced nausea and vomiting (CINV) | drug-drug interactions | P-glycoprotein (P-gp) | chemotherapy-induced nausea and vomiting (CINV) | neurokinin-1 (NK-1) | CHEMOTHERAPY-INDUCED NAUSEA | EFFICACY | VOMITING CINV | PREVENTION | RECEPTOR ANTAGONIST | HIGHLY EMETOGENIC CHEMOTHERAPY | TRANSPORT | DRUG DEVELOPMENT | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | ABCG2 | Neurokinin-1 Receptor Antagonists - adverse effects | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Administration, Oral | Humans | Middle Aged | Spiro Compounds - administration & dosage | Male | Neurokinin-1 Receptor Antagonists - administration & dosage | Healthy Volunteers | Neoplasm Proteins - metabolism | Spiro Compounds - adverse effects | Digoxin - pharmacokinetics | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Administration, Intravenous | Drug Interactions | Sulfasalazine - pharmacokinetics | Adult | Female | Prevention | Nausea | Pharmacokinetics | Vomiting | Analysis | EKG | Intravenous administration | Digoxin | Toxicity | Glycoprotein | Glycoproteins | Breast cancer | Pharmacology | Substrates | Confidence intervals | Chemotherapy | Neurokinin NK1 receptors | Neurokinin | Sulfasalazine | Adults | P-Glycoprotein | Cancer | Index Medicus
Journal Article
BMC Cancer, ISSN 1471-2407, 02/2018, Volume 18, Issue 1, pp. 153 - 10
The UDP-glucose ceramide glycosyltransferase (UGCG) is a key enzyme in the sphingolipid metabolism by generating glucosylceramide (GlcCer), the precursor for... 
UGCG | MDR1 | UDP-glucose ceramide glycosyltransferase | Glycosphingolipids | P-gp | Multidrug resistance | Cancer | PATHWAYS | APOPTOSIS | GLUCOSYLCERAMIDE SYNTHASE | DRUG-RESISTANCE | IDENTIFICATION | P-GLYCOPROTEIN | BREAST-CANCER CELLS | ONCOLOGY | MULTIDRUG-RESISTANCE | EXPRESSION | MEMBRANE-LIPIDS | Analysis | Sphingolipids | Research | Drug resistance | Gene expression | Metabolism
Journal Article
Cancer Letters, ISSN 0304-3835, 2012, Volume 328, Issue 2, pp. 307 - 317
Highlights ► Nilotinib compared to panel of tyrosine kinase inhibitors most potently reverse ABCB1, ABCG2 and ABCC10 transporters mediated drug resistance. ►... 
Hematology, Oncology and Palliative Medicine | Nilotinib | ABCB1/P-gp | ABC transporters | ABCG2/BCRP | Multidrug resistance | ABCC10/MRP7 | CANCER-CELLS | TRANSPORTERS | BCR-ABL | SUBFAMILY-B MEMBER-1 | TYROSINE KINASE INHIBITORS | IN-VITRO | PROTEIN BCRP/ABCG2 | ONCOLOGY | IMATINIB | REVERSES MULTIDRUG-RESISTANCE | BINDING | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | Male | Antineoplastic Agents - administration & dosage | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | Neoplasms - genetics | HEK293 Cells | Multidrug Resistance-Associated Proteins - genetics | Tumor Burden - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Pyrimidines - administration & dosage | Multidrug Resistance-Associated Proteins - chemistry | Neoplasm Proteins - chemistry | Pyrimidines - pharmacology | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Animals | Tumor Burden - drug effects | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Mice, Nude | Cell Line, Tumor | Protein Conformation | ATP Binding Cassette Transporter, Sub-Family B | Mice | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Tyrosine | Drug resistance in microorganisms | Anthracyclines | Care and treatment | Epidermal growth factor | Analysis | Universities and colleges | Cancer | Laboratories | Cytotoxicity | Bioavailability | Kinases | Metabolism | Drug resistance | DNA repair | Proteins | Studies | Chemotherapy | Metabolites | Tumors | Index Medicus | BCRP | multidrug resistance | ABCB1 | P-gp | MRP7 | ABCC10 | ABCG2
Journal Article