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Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 13, pp. 11180 - 11196
Four out of five patients diagnosed with esophageal squamous cell carcinoma (ESCC) will die within five years. This is primarily a result of the aggressive... 
P120-catenin | ESCC invasion | NFkB | EGFR | RhoA
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/2003, Volume 163, Issue 3, pp. 525 - 534
p120-catenin stabilizes epithelial cadherin (E-cadherin) in SW48 cells, but the mechanism has not been established. Here, we show that p120 acts at the cell... 
Epithelial cells | Cell lines | Cell adhesion | Small interfering RNA | Cadherins | Mice | Gene expression regulation | Cells | Catenins | Tumors | Metastasis | Tumor suppressor | p120-catenin | Tumor progression | RHO-FAMILY GTPASES | PROTEIN | tumor suppressor | P120 CATENIN | BETA-CATENIN | CELL BIOLOGY | tumor progression | metastasis | cell adhesion | CELL-CELL-ADHESION | TYROSINE KINASE SUBSTRATE | EXPRESSION | BINDING | HUMAN CANCER | N-CADHERIN | Neoplasms - metabolism | Cell Adhesion Molecules - genetics | Cadherins - metabolism | Cytoskeletal Proteins - genetics | Humans | Cell Adhesion Molecules - antagonists & inhibitors | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | Adherens Junctions - metabolism | Armadillo Domain Proteins | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Cytoskeletal Proteins - metabolism | Cell Membrane - metabolism | Cadherins - genetics | Adherens Junctions - genetics | RNA, Small Interfering - pharmacology | Phosphoproteins - genetics | Cell Adhesion Molecules - metabolism | Cell Transformation, Neoplastic - metabolism | Down-Regulation - genetics | Cell Adhesion - physiology | Models, Biological | Cell Line, Tumor | Cytology | Research | Cellular biology | Ribonucleic acid--RNA | Ribonucleic acid | Index Medicus | tumor suppressor; p120-catenin; cell adhesion; tumor progression; metastasis
Journal Article
World neurosurgery, ISSN 1878-8750, 04/2019, Volume 128, pp. e177 - e184
Dysfunction of endothelial cells (ECs) constitutes a critical factor in the formation of intracranial aneurysms (IAs). However, little is known about the... 
Rabbits | Intracranial aneurysms | Analysis | Cells | Endothelium
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 12/2005, Volume 65, Issue 23, pp. 10938 - 10945
We examined the expression and localization of p120 catenin (p120ctn) as a consequence of the epithelial to mesenchymal transition (EMT) of highly... 
ADHESION | BREAST-CARCINOMA | INHIBITION | TUMOR PROGRESSION | GTPASES | ONCOLOGY | RHO | E-CADHERIN | EXPRESSION | P120-CATENIN | HUMAN COLORECTAL-CANCER
Journal Article
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, ISSN 1000-1182, 04/2017, Volume 35, Issue 2, pp. 183 - 186
Journal Article
FASEB Journal, ISSN 0892-6638, 01/2019, Volume 33, Issue 1, pp. 1199 - 1208
Tumor vasculature is known to be more permeable than the vasculature found in healthy tissue, which in turn can lead to a more aggressive tumor phenotype and... 
Substrate compliance | Endothelial barrier function | VE-cadherin | endothelial barrier function | METASTASIS | TYROSINE PHOSPHORYLATION | PERMEABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | P120-CATENIN | CELL BIOLOGY | BARRIER DISRUPTION | FAK | substrate compliance | INHIBITION | EXTRAVASATION | BIOLOGY
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 2015, Volume 208, Issue 1, pp. 23 - 32
The role of the RhoGTPase Rac1 in stabilizing mature endothelial adherens junctions (AJs) is not well understood. In this paper, using a photoactivatable probe... 
ENDOTHELIAL ADHERENS JUNCTIONS | ACTIVATION | HOMEOSTASIS | SPATIOTEMPORAL REGULATION | PERMEABILITY | P190RHOGAP | RHO | CELL-CELL ADHESION | BINDING | P120-CATENIN | CELL BIOLOGY | Enzymes | Chromatin | Kinases | Cell adhesion & migration | Index Medicus
Journal Article
WORLD NEUROSURGERY, ISSN 1878-8750, 08/2019, Volume 128, pp. E177 - E184
BACKGROUND: Dysfunction of endothelial cells (ECs) constitutes a critical factor in the formation of intracranial aneurysms (IAs). However, little is known... 
SURGERY | WILLIS | TRANSCRIPTION | INJURY | Endothelial cells | CLINICAL NEUROLOGY | Intracerebral aneurysm | CIRCLE | BASILAR TERMINUS | RESPONSES | p120-catenin | VE-cadherin | GROWTH | SMOOTH-MUSCLE-CELLS | Hemodynamics
Journal Article
Current Biology, ISSN 0960-9822, 02/2019, Volume 29, Issue 4, pp. 578 - 591.e5
Studying how epithelia respond to mechanical stresses is key to understanding tissue shape changes during morphogenesis. Here, we study the viscoelastic... 
laser ablation | morphogenesis | mechanotransduction | viscoelasticity | p120-catenin | mechanical stress | endocytosis | E-cadherin turnover | SHAPE CHANGES | ORGANIZATION | PHOSPHORYLATION | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TISSUE SHAPE | P120 CATENIN | ADHERENS JUNCTIONS | CELL-SHAPE | BINDING | P120-CATENIN | CELL BIOLOGY | Cells | Protein binding
Journal Article
BMC Cancer, ISSN 1471-2407, 02/2019, Volume 19, Issue 1, pp. 171 - 171
BackgroundEpithelial ovarian cancer (EOC) remains one of the most lethal gynecologic cancers, and its pathogenetic mechanism remains unclear. Here we show that... 
Proliferation | MUC16 | Epithelial ovarian cancer | Migration | p120-catenin | METASTASIS | P120 CATENIN | BETA-CATENIN | MESENCHYMAL TRANSITION | CA125/MUC16 | ADHESION | ONCOLOGY | EXPRESSION | TUMORIGENESIS | ANTIGEN | MOTILITY | Infection | Analysis | Oncology, Experimental | Genomics | Mucins | G proteins | Research | Ovarian cancer | Cancer
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 01/2019, Volume 234, Issue 1, pp. 427 - 432
The results from keratinocyte specific p120cKO in adult mice showed that epidermal differentiation and permeability barrier function were reduced and... 
p120‐catenin | differentiation | proliferation | barrier function | epidermis | p120-catenin | PHYSIOLOGY | PHOSPHORYLATION | TRANSEPIDERMAL WATER-LOSS | P120 CATENIN | CELL-ADHESION | E-CADHERIN | BETA-CATENIN | CELL BIOLOGY | INVASION | INHIBITION | VE-CADHERIN | ABERRANT EXPRESSION | Permeability | Epidermis | Differentiation | Catenin | E-cadherin
Journal Article
JOURNAL OF PATHOLOGY, ISSN 0022-3417, 08/2018, Volume 245, Issue 4, pp. 456 - 467
Although mutational inactivation of E-cadherin (CDH1) is the main driver of invasive lobular breast cancer (ILC), approximately 10-15% of all ILCs retain... 
mouse model | alpha-catenin (CTNNA1) | lobular breast cancer | P120 CATENIN | PATHOLOGY | ANOIKIS RESISTANCE | E-cadherin | P120-CATENIN | RHOA | Rho/Rock | ONCOLOGY | GASTRIC-CANCER | ALPHA-CATENIN | GROWTH | MUTATIONS | CELL-CELL ADHESION | CARCINOMA | Development and progression | Analysis | Breast cancer
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 38, pp. 63764 - 63779
microRNA (miRNA) dysregulation is frequently observed in colon cancer. Previous studies found that miR-223 is upregulated in colon cancer and functions as an... 
β-catenin | MiR-223 | P120 | Colon cancer | RhoA | beta-catenin | colon cancer | E-CADHERIN | KAPPA-B | p120 | P120-CATENIN | CELL BIOLOGY | miR-223 | COLORECTAL-CANCER | CELL-MIGRATION | POOR SURVIVAL | PROSTATE-CANCER | EXPRESSION | CARCINOMA
Journal Article
Oncogene, ISSN 0950-9232, 01/2017, Volume 36, Issue 3, pp. 429 - 438
Canonical Wnt signaling induces the stabilization of beta-catenin, its translocation to the nucleus and the activation of target promoters. This pathway is... 
REGULATORY SUBUNIT | TRANSCRIPTIONAL ACTIVITY | COMPLEX | DOMAIN | LRP6 PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN PHOSPHATASE 2A | BETA-CATENIN | CASEIN KINASE 1 | P120-CATENIN | CELL BIOLOGY | ONCOLOGY | GENETICS & HEREDITY | BINDING
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 08/2019, Volume 58, Issue 8, pp. 1389 - 1399
Hepatocellular carcinoma (HCC) is a fatal disease with increasing morbidity and poor prognosis due to surgical recurrence and metastasis. Moreover, the... 
p120‐catenin | exosome | hepatocellular carcinoma | STAT3 | ONCOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | p120-catenin | CANCER STEM-CELL | CATENIN | Development and progression | Stem cells | Hepatoma | Cell proliferation | Liver | Stat3 protein | Hepatocellular carcinoma | Metastasis | Exosomes | Morbidity | Metastases | Liver cancer | Hepatocytes | Catenin | Cancer
Journal Article