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by Wu, D and Wang, LP and Yang, YH and Huang, J and Hu, YH and Shu, YW and Zhang, JY and Zheng, J
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 03/2018, Volume 498, Issue 1, pp. 157 - 163
Mitotic arrest deficient-like-1 (MAD2, also known as MAD2L1) is thought to be an important spindle assembly checkpoint protein, which ensures accurate... 
Cell proliferation | CANCER-CELLS | MAD2 | CHROMOSOME INSTABILITY | p31(comet) | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPINDLE ASSEMBLY CHECKPOINT | Microtubule-interfering agents | IN-VITRO | BIOPHYSICS | Glioma | GENE-EXPRESSION | MALIGNANT GLIOMAS | MAD2 OVEREXPRESSION | MITOTIC CHECKPOINT | TUMORIGENESIS
Journal Article
by Ji, JH and Tang, D and Shen, Y and Xue, ZH and Wang, HJ and Shi, WQ and Zhang, C and Du, GJ and Li, YF and Cheng, ZK
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 09/2016, Volume 113, Issue 38, pp. 10577 - 10582
The human mitotic arrest-deficient 2 (Mad2) binding protein p31(comet) participates in the spindle checkpoint and coordinates cell cycle events in mitosis... 
DSB formation | meiosis | p31(comet) | MULTIDISCIPLINARY SCIENCES | HOMOLOGOUS CHROMOSOME SYNAPSIS | rice | IDENTIFICATION | synaptonemal complex | STRAND BREAK FORMATION | RECOMBINATION INITIATION | MITOSIS | CONSERVATION | MAD2-BINDING PROTEIN | CHECKPOINT | METAPHASE I
Journal Article
SPRINGERPLUS, ISSN 2193-1801, 2013, Volume 2, p. 562
Mad2 is a key component of the spindle assembly checkpoint (SAC) that delays the onset of anaphase until all kinetochores are attached to the spindle. It binds... 
Anti-mitotic drug | Drug resistance | Spindle assembly checkpoint | p31(comet) | Mad2 | MULTIDISCIPLINARY SCIENCES
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 11/2012, Volume 19, Issue 11, pp. 1116 - 1123
The anaphase-promoting complex/cyclosome (APC/C) bound to CDC20 (APC/C-CDC20) initiates anaphase by ubiquitylating B-type cyclins and securin. During... 
ANAPHASE-PROMOTING COMPLEX | PROTEIN | BUDDING YEAST | BIOCHEMISTRY & MOLECULAR BIOLOGY | BAC TRANSGENEOMICS | COACTIVATOR CDH1 | P31(COMET) | SPINDLE ASSEMBLY CHECKPOINT | MAD2 ACTIVATION | CELL BIOLOGY | UBIQUITINATION | BIOPHYSICS | BINDING
Journal Article
Cell Cycle, ISSN 1538-4101, 12/2015, Volume 14, Issue 24, pp. 3978 - 3985
p31 comet plays an important role in spindle assembly checkpoint (SAC) silencing. However, how p31 comet 's activity is regulated remains unclear. Here we show... 
Xenopus | inhibitor of nuclear factor κ-B kinase-β | Spindle assembly checkpoint | Mad2 | comet | IKK-β | p31
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 02/2018, Volume 22, Issue 6, pp. 1439 - 1450
The spindle assembly checkpoint (SAC) prevents premature segregation of chromosomes during mitosis. This process requires structural remodeling of MAD2 from... 
MAD2 | TRIP13 | mitosis | spindle assembly checkpoint | ATPASE TRIP13 | CELLS | HORMA DOMAINS | COMPLEX | PROTEIN MAD2 | CHROMOSOME MISSEGREGATION | AAA-ATPASE | P31(COMET) | MAD2 ACTIVATION | UNATTACHED KINETOCHORES | CELL BIOLOGY
Journal Article
Cell Cycle, ISSN 1538-4101, 12/2013, Volume 12, Issue 24, pp. 3824 - 3832
p31 Comet is a well-known interacting partner of the spindle assembly checkpoint (SAC) effector molecule Mad2. At the molecular level it is well established... 
Rb | Comet | cell cycle | spindle assembly checkpoint | Mad2 | E2F | cancer | p31
Journal Article
Journal Article
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