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Nature, ISSN 0028-0836, 2013, Volume 495, Issue 7439, pp. 107 - 110
Journal Article
Nature, ISSN 0028-0836, 08/2015, Volume 524, Issue 7565, pp. 361 - 365
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2009, Volume 460, Issue 7257, pp. 904 - 908
Acquired uniparental disomy (aUPD) is a common feature of cancer genomes, leading to loss of heterozygosity. aUPD is associated not only with loss-of-function... 
TRANSFORMATION | PROTEIN | RETROVIRAL VECTOR GCDNSAP | NEGATIVE REGULATION | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | V-CBL | MUTATIONS | UBIQUITIN LIGASES | MYELODYSPLASTIC SYNDROMES | P53 | NIH 3T3 Cells | Neoplasm Transplantation | ras Proteins - genetics | Phosphorylation | Proto-Oncogene Proteins c-cbl - metabolism | Humans | Leukemia, Myeloid - genetics | Molecular Sequence Data | ras Proteins - metabolism | Male | Leukemia, Myeloid - pathology | Allelic Imbalance | Ubiquitination | Base Sequence | Female | Proto-Oncogene Proteins c-cbl - deficiency | Genes, Tumor Suppressor | Proto-Oncogene Proteins c-cbl - genetics | Amino Acid Sequence | Oncogenes - genetics | Mutant Proteins - genetics | Models, Molecular | Mutant Proteins - metabolism | Chromosomes, Human, Pair 11 - genetics | Proto-Oncogene Proteins c-cbl - chemistry | Mice, Knockout | Animals | Uniparental Disomy - genetics | Leukemia, Myeloid - metabolism | Mice, Nude | Mutant Proteins - chemistry | Proto-Oncogene Proteins c-cbl - antagonists & inhibitors | Protein Conformation | Mice | Mutation | Gene mutations | Myelocytic leukemia | Physiological aspects | Tumor suppressor genes | Development and progression | Genetic aspects | Nonlymphoid leukemia | Research | Protein kinases | Proteins | Genes | Amino acids | Kinases | Cells | Clinical outcomes | Crystal structure | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 10/2014, Volume 514, Issue 7524, pp. 628 - 632
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers in western countries, with a median survival of 6 months and an extremely low... 
STEM-CELLS | INHIBITION | MELANOMA | METABOLISM | GLUCOSE | MULTIDISCIPLINARY SCIENCES | IMATINIB | LEUKEMIA | AUTOPHAGY | INDUCTION | TUMOR-GROWTH | Recurrence | Pancreatic Neoplasms - metabolism | Neoplastic Stem Cells - drug effects | Proto-Oncogene Proteins p21(ras) - genetics | Carcinoma, Pancreatic Ductal - metabolism | Gene Expression Regulation, Neoplastic | Autophagy | Carcinoma, Pancreatic Ductal - genetics | Oxidative Phosphorylation - drug effects | Pancreatic Neoplasms - drug therapy | Lysosomes - metabolism | Neoplastic Stem Cells - metabolism | Cell Respiration - drug effects | Neoplastic Stem Cells - pathology | Female | Disease Models, Animal | Proto-Oncogene Proteins p21(ras) - metabolism | Cell Survival - drug effects | Neoplasm Recurrence, Local - prevention & control | Signal Transduction | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Mitochondria - metabolism | Genes, p53 - genetics | Mitochondria - drug effects | Mutation - genetics | Carcinoma, Pancreatic Ductal - pathology | Carcinoma, Pancreatic Ductal - drug therapy | Animals | Glycolysis | Mice | Protein research | Ablation (Surgery) | Care and treatment | Pancreatic cancer | Oncology, Experimental | Genetic aspects | Research | Cancer | Mitochondria | Stem cells | Cell cycle | Lipids | Metabolism | Tumors | Apoptosis | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 10/2016, Volume 92, Issue 2, pp. 383 - 391
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 8, pp. 3116 - 3121
Journal Article