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Journal of Clinical Investigation, ISSN 0021-9738, 02/1998, Volume 101, Issue 4, pp. 777 - 782
The p21 protein is found in the nucleus of most cells at low levels and is induced to elevated levels after DNA damage, causing cell-cycle arrest. We have... 
Cyclin-dependent kinase | DNA damage | Cell cycle | Apoptosis | Necrosis | WILD-TYPE P53 | MEDICINE, RESEARCH & EXPERIMENTAL | cell cycle | TUMOR-SUPPRESSOR GENE | CYCLE ARREST | apoptosis | CDK INHIBITOR | DEPENDENT KINASE INHIBITOR | P21 | DNA-REPLICATION | necrosis | GROWTH ARREST | P53-MEDIATED G ARREST | LEUKEMIA-CELLS | cyclin-dependent kinase
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/1996, Volume 227, Issue 2, pp. 564 - 569
Proteasome-dependent degradation of regulatory proteins is a known mechanism of cell cycle control. We found that the proteasome-specific inhibitor lactacystin... 
APOPTOSIS | BIOPHYSICS | GROWTH ARREST | PATHWAY | P53-MEDIATED G ARREST | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEGRADATION | LACTACYSTIN | CELL-LINES | INHIBITOR | CYCLIN | P53
Journal Article
ONCOGENE, ISSN 0950-9232, 10/1998, Volume 17, Issue 13, pp. 1691 - 1703
p21(Waf1/Cip1) is a major transcriptional target of p53 and has been shown to be one of the principal mediators of the p53 induced G1 cell cycle arrest. We... 
WILD-TYPE P53 | endoreduplication | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN CANCER-CELLS | cell cycle arrest | CELL BIOLOGY | cyclin dependent kinase | senescence | CDK INHIBITORS | RETINOBLASTOMA PROTEIN | ONCOLOGY | GROWTH ARREST | P53-MEDIATED G ARREST | IN-VIVO | GENETICS & HEREDITY | DEPENDENT-KINASE INHIBITOR | S-PHASE | HUMAN FIBROBLASTS | p21(Waf1/Cip1)
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 02/2012, Volume 11, Issue 2, pp. 370 - 382
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 50, pp. 83071 - 83087
Journal Article
Immunology, ISSN 0019-2805, 06/2008, Volume 124, Issue 2, pp. 234 - 246
Journal Article
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 01/2012, Volume 31, Issue 3, pp. 366 - 375
Journal Article