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phosphorylation (75) 75
animals (68) 68
biochemistry & molecular biology (57) 57
humans (54) 54
p90 (51) 51
cell biology (48) 48
map kinase (42) 42
ribosomal protein s6 kinases, 90-kda - metabolism (42) 42
p90 ribosomal s6 kinase (41) 41
enzyme activation (27) 27
ribosomal s6 kinase (26) 26
signal transduction (26) 26
p90 rsk (23) 23
activation (22) 22
rsk (22) 22
female (21) 21
mitogen-activated protein kinases - metabolism (21) 21
protein-kinase (21) 21
ribosomal protein s6 kinases, 90-kda - antagonists & inhibitors (19) 19
ribosomal protein s6 kinases, 90-kda - genetics (19) 19
mice (18) 18
activated protein-kinase (17) 17
meiosis (17) 17
pathway (17) 17
biophysics (16) 16
expression (15) 15
cancer (14) 14
cell line, tumor (14) 14
life sciences (14) 14
map kinase signaling system (14) 14
mapk, mitogen-activated protein kinase (14) 14
protein kinase inhibitors - pharmacology (14) 14
rsk, p90 ribosomal s6 kinase (14) 14
amino acid sequence (13) 13
cell line (13) 13
molecular sequence data (13) 13
protein-serine-threonine kinases - metabolism (13) 13
enzyme inhibitors - pharmacology (12) 12
erk, extracellular-signal-regulated kinase (12) 12
identification (12) 12
in-vivo (12) 12
mapk (12) 12
meiotic maturation (12) 12
research article (12) 12
ribosomal protein s6 kinases - metabolism (12) 12
docking site (11) 11
male (11) 11
mitogen-activated protein kinase (11) 11
mos (11) 11
oocytes - metabolism (11) 11
pkb, protein kinase b (11) 11
protein kinases (11) 11
signal transduction - drug effects (11) 11
signal-transduction (11) 11
cells, cultured (10) 10
egf, epidermal growth factor (10) 10
inhibitor (10) 10
mouse oocytes (10) 10
oocytes - cytology (10) 10
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rats (10) 10
cell cycle (9) 9
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blotting, western (8) 8
cleaving xenopus-embryos (8) 8
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erk (8) 8
growth (8) 8
gst, glutathione s-transferase (8) 8
kinase (8) 8
kinases (8) 8
mitosis (8) 8
phosphorylation - drug effects (8) 8
proteins (8) 8
s6 kinase (8) 8
substrate specificity (8) 8
xenopus laevis (8) 8
binding sites (7) 7
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inhibition (7) 7
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models, molecular (7) 7
oocyte (7) 7
oocytes - physiology (7) 7
phosphoserine - metabolism (7) 7
pkc, protein kinase c (7) 7
rats, sprague-dawley (7) 7
receptor (7) 7
recombinant fusion proteins - metabolism (7) 7
ribosomal protein s6 kinases, 90-kda - chemistry (7) 7
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xenopus proteins - metabolism (7) 7
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Biochemical journal, ISSN 1470-8728, 2007, Volume 401, Issue 1, pp. 29 - 38
Hormones and growth factors induce the activation of a number of protein kinases that belong to the AGC subfamily, including isoforms of PKA, protein kinase B (also known as Akt), PKC, S6K p70 (ribosomal S6 kinase), RSK... 
Kinase-specific inhibitor | Phosphorylation | p90 ribosomal S6 kinase (RSK) | BI-D1870 | Mitogen-activated protein kinase (MAPK) | ACTIVATED PROTEIN-KINASE | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | mitogen-activated protein kinase (MAPK) | MSK1 | INDUCTION | IDENTIFICATION | INACTIVATION | CREB | GROWTH | BI-DI870 | SUPPRESSES | phosphorylation | kinase-specific inhibitor | Cell Line | Pteridines - pharmacology | Humans | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Rats | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Animals | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Ribosomal Protein S6 Kinases, 90-kDa - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Kinetics | Chromones - pharmacology | Isoenzymes - antagonists & inhibitors | MES, mouse embryonic stem | PI3K, phosphoinositide 3-kinase | EGF, epidermal growth factor | PKA, cAMP-dependent protein kinase A | FKHR, forkhead in rhabdosarcoma transcription factor | RSK, p90 ribosomal S6 kinase | JNK, c-Jun N-terminal kinase | CREB, cAMP-response-element-binding protein | SGK1, serum- and glucocorticoid-induced kinase-1 | PDK1, phosphoinositide-dependent kinase 1 | PKB, protein kinase B | Lck, lymphocyte kinase | ROCK, Rho-dependent protein kinase | MKK1, MAPK kinase-1 | protein kinase G | AGC, cAMP-dependent protein kinase | protein kinase C | HEK-293, human embryonic kidney 293 | ERK1, extracellular-signal-regulated kinase 1 | GST, glutathione S-transferase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | PH, pleckstrin homology | PLK1, polo-like kinase 1 | CK1, casein kinase-1 | FBS, foetal bovine serum | MSK, mitogen- and stress-activated protein kinase | CDK2–A, cyclin-dependent kinase 2 complexed with cyclin A | DYRK1a, dual-specificity tyrosine-phosphorylated and -regulated kinase 1a | GSK3α, glycogen synthase kinase 3α | MAPK, mitogen-activated protein kinase
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 12/2011, Volume 286, Issue 48, pp. 41171 - 41182
Open reading frame 45 (ORF45) of Kaposi sarcoma-associated herpesvirus (KSHV) causes sustained activation of p90 ribosomal 56 kinase (RSK... 
IN-VITRO | HELICASE ACTIVITY | ENTRY SITE | BACTERIAL ARTIFICIAL CHROMOSOME | FACTOR EIF-4B | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRIMARY EFFUSION LYMPHOMA | GENE-EXPRESSION | TUBEROUS SCLEROSIS | VACCINIA VIRUS | MAPK PATHWAYS | Gene Expression Regulation, Viral - drug effects | Protein Biosynthesis | TOR Serine-Threonine Kinases - metabolism | Humans | Proto-Oncogene Proteins c-akt - genetics | MAP Kinase Signaling System | TOR Serine-Threonine Kinases - antagonists & inhibitors | Immediate-Early Proteins - metabolism | Phosphorylation - genetics | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | TOR Serine-Threonine Kinases - genetics | HEK293 Cells | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Immunosuppressive Agents - pharmacology | Herpesvirus 8, Human - physiology | Eukaryotic Initiation Factors - genetics | Eukaryotic Initiation Factors - metabolism | Gene Expression Regulation, Viral - physiology | Virus Replication - drug effects | Sirolimus - pharmacology | Immediate-Early Proteins - genetics | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Cell Line, Tumor | Mutation | Virus Replication - physiology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Gene Regulation | Virus | MAP Kinases (MAPKs) | eIF4B | Phosphorylation | Tegument | Translation Regulation | Kaposi Sarcoma Associated Herpesvirus (KSHV) | p90 Ribosomal S6 Kinase (RSK) | ORF45 | Translation Initiation Factors
Journal Article
ACS medicinal chemistry letters, ISSN 1948-5875, 02/2013, Volume 4, Issue 2, pp. 175 - 179
Journal Article
Journal Article
Cellular signalling, ISSN 0898-6568, 2015, Volume 27, Issue 8, pp. 1630 - 1642
The 90kDa ribosomal S6 kinases (RSK) are effectors of the Ras-ERK1/2 signaling pathway... 
p70 ribosomal S6 kinase (p70S6K) | Tuberin (TSC2) | SL0101 | BI-D1870 | Ribosomal protein S6 (rpS6) | p90 kDa ribosomal S6 kinase (RSK) | P70 ribosomal S6 kinase (p70S6K) | P90 kDa ribosomal S6 kinase (RSK) | ACTIVATION | RAS-ERK | PHOSPHORYLATION | PROTEIN-KINASE | CANCER | FAMILY | CELL BIOLOGY | IN-VITRO | OVERCOMING RESISTANCE | GROWTH | RIBOSOMAL S6 KINASE | Glioblastoma - enzymology | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Humans | Substrate Specificity | Data Mining | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | Dose-Response Relationship, Drug | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Transfection | Glioblastoma - genetics | RNA Interference | Time Factors | HEK293 Cells | Ribosomal Protein S6 Kinases, 90-kDa - antagonists & inhibitors | Benzopyrans - pharmacology | Pteridines - pharmacology | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction - drug effects | Glioblastoma - pathology | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Cell Line, Tumor | Monosaccharides - pharmacology | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Tumor Suppressor Proteins | Phosphotransferases | Protein biosynthesis | Epidermal growth factor | Genetic translation | Mitogens | Protein kinases | Protein binding
Journal Article
Expert Opinion on Therapeutic Targets, ISSN 1472-8222, 01/2011, Volume 15, Issue 1, pp. 1 - 4
Journal Article
Journal Article
FEBS LETTERS, ISSN 0014-5793, 01/2010, Volume 584, Issue 1, pp. 124 - 128
.... Here, we dissect the signaling pathways responsible for Ser167 phosphorylation. We report that the mTOR/S6K1 and MAPK/RSK contribute non-overlapping inputs into ER alpha activation via Ser167 phosphorylation... 
TARGET | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | Rapamycin | Breast cancer | CELL-GROWTH | CANCER | NUTRIENT | CELL BIOLOGY | p70 S6 kinase 1 | MEK | INHIBITION | BIOPHYSICS | Mammalian target of rapamycin | Estrogen receptor alpha | p90 ribosomal S6 kinase | GROWTH-FACTOR | S6 KINASE | Phenols | Care and treatment | Protein kinases | Estrogen | Cancer
Journal Article
Nature chemical biology, ISSN 1552-4450, 03/2007, Volume 3, Issue 3, pp. 138 - 139
Journal Article
Trends in Cancer, ISSN 2405-8033, 04/2017, Volume 3, Issue 4, pp. 302 - 312
Journal Article