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index medicus (122) 122
animals (84) 84
pac1 protein (64) 64
cyclase-activating polypeptide (59) 59
neurosciences (59) 59
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pituitary adenylate cyclase-activating polypeptide (57) 57
humans (46) 46
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receptors, pituitary adenylate cyclase-activating polypeptide, type i - metabolism (35) 35
pharmacology & pharmacy (32) 32
pituitary adenylate cyclase-activating polypeptide - metabolism (31) 31
biochemistry & molecular biology (30) 30
pituitary adenylate cyclase-activating polypeptide - pharmacology (30) 30
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analysis (24) 24
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peptides (17) 17
signal transduction (17) 17
vasoactive intestinal peptide - pharmacology (17) 17
endocrine system (15) 15
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biomedicine (14) 14
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molecular sequence data (13) 13
peptide (13) 13
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receptors, pituitary adenylate cyclase-activating polypeptide, type i - genetics (13) 13
blood platelets (12) 12
cells, cultured (12) 12
inflammation (12) 12
neurons - metabolism (12) 12
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rats, sprague-dawley (11) 11
receptors, pituitary adenylate cyclase-activating polypeptide, type i - agonists (11) 11
receptors, pituitary adenylate cyclase-activating polypeptide, type i - antagonists & inhibitors (11) 11
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Journal of Molecular Neuroscience, ISSN 0895-8696, 10/2016, Volume 60, Issue 2, pp. 186 - 194
Journal Article
Peptides, ISSN 0196-9781, 2008, Volume 29, Issue 6, pp. 919 - 932
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38- or 27-amino acid neuropeptide with promising therapeutic applications for the treatment of... 
Plasma metabolites | Stable analogs | PAC1 receptor agonists | Dipeptidyl peptidase IV | PACAP | CEREBELLAR GRANULE NEURONS | CYCLASE-ACTIVATING POLYPEPTIDE | VASOACTIVE-INTESTINAL-PEPTIDE | stable analogs | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | ENDOGENOUS PACAP | plasma metabolites | GLUCAGON-LIKE PEPTIDE-1 | STRUCTURAL REQUIREMENTS | IN-VIVO | PC-12 CELLS | dipeptidyl peptidase IV | PHARMACOLOGY & PHARMACY | ADENYLATE-CYCLASE | Cricetulus | Humans | Pituitary Adenylate Cyclase-Activating Polypeptide - chemical synthesis | Molecular Sequence Data | PC12 Cells | Dose-Response Relationship, Drug | Pituitary Adenylate Cyclase-Activating Polypeptide - isolation & purification | Protein Isoforms - metabolism | Time Factors | Protein Isoforms - chemistry | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - blood | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | CHO Cells | Amino Acid Sequence | Cricetinae | Cell Size - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - chemistry | Rats | Electroporation | Animals | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - drug effects | Cell Differentiation - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Protein Binding | Cell Proliferation - drug effects | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | DNA, Complementary | Protein Isoforms - genetics | Index Medicus
Journal Article
Journal Article
Peptides, ISSN 0196-9781, 2008, Volume 29, Issue 8, pp. 1347 - 1353
Journal Article
Cephalalgia, ISSN 0333-1024, 1/2011, Volume 31, Issue 2, pp. 181 - 189
Objective: We pharmacologically characterized pituitary adenylate cyclase–activating polypeptides (PACAPs), vasoactive intestinal peptide (VIP) and the VPAC1,... 
PAC1 | PACAP38 | VPAC1 | VIP | VPAC2 | CYCLASE-ACTIVATING POLYPEPTIDE | RAT | IMMUNOHISTOCHEMICAL LOCALIZATION | MIGRAINE | NEUROSCIENCES | PEPTIDE | CLINICAL NEUROLOGY | PAC | VPAC | MESSENGER-RNA | HEADACHE | CEREBRAL-ARTERIES | HEALTHY-VOLUNTEERS | EXPRESSION | Pituitary Adenylate Cyclase-Activating Polypeptide - antagonists & inhibitors | Receptors, Vasoactive Intestinal Polypeptide, Type I - antagonists & inhibitors | Gene Expression - drug effects | Receptors, Vasoactive Intestinal Peptide, Type II - agonists | Humans | Middle Aged | Male | Peptide Fragments - pharmacology | Receptors, Vasoactive Intestinal Peptide - genetics | RNA, Messenger - metabolism | Receptors, Vasoactive Intestinal Peptide, Type II - genetics | Meningeal Arteries - physiology | Vasoactive Intestinal Peptide - pharmacology | Receptors, Vasoactive Intestinal Polypeptide, Type I - agonists | Gene Expression - physiology | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Migraine Disorders - physiopathology | Adult | Female | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - agonists | Vasodilation - physiology | Coronary Vessels - drug effects | Receptors, Vasoactive Intestinal Peptide, Type II - antagonists & inhibitors | Vasodilator Agents - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Coronary Vessels - physiology | Pituitary Adenylate Cyclase-Activating Polypeptide - adverse effects | Meningeal Arteries - drug effects | Migraine Disorders - drug therapy | Receptors, Vasoactive Intestinal Polypeptide, Type I - genetics | Aged | Receptors, Vasoactive Intestinal Peptide - antagonists & inhibitors | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Vasodilation - drug effects | Receptors, Vasoactive Intestinal Peptide - agonists | Vasoactive Intestinal Peptide - analogs & derivatives | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - antagonists & inhibitors | Index Medicus
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2011, Volume 670, Issue 1, pp. 186 - 194
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating peptide (PACAP) are potent vasodilators in animals and humans. PACAP infusion... 
PACAP | VPAC1 | Migraine | VPAC2 | PAC1 | VIP | Myograph | In situ hybridization | Neuropeptide | Perfusion myograph | PAC | VPAC | POLYPEPTIDE VIP | VASOACTIVE-INTESTINAL-PEPTIDE | NERVES | IMMUNOHISTOCHEMICAL LOCALIZATION | MENINGEAL | MESSENGER-RNA | NEURONS | PHARMACOLOGY & PHARMACY | VASODILATION | CEREBRAL-ARTERIES | Myography | Angiography | Humans | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Male | Receptors, Vasoactive Intestinal Peptide - genetics | RNA, Messenger - metabolism | Arteries - metabolism | Receptors, Vasoactive Intestinal Peptide - metabolism | Vasoactive Intestinal Peptide - pharmacology | Arteries - physiology | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - agonists | RNA, Messenger - genetics | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - antagonists & inhibitors | Rats | Arteries - drug effects | Pressure | Rats, Sprague-Dawley | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Gene Expression Regulation - drug effects | Animals | Ligands | Receptors, Vasoactive Intestinal Peptide - antagonists & inhibitors | In Vitro Techniques | Receptors, Vasoactive Intestinal Peptide - agonists | RNA | Vasoactive intestinal peptides | Vasodilators | Arteries | Index Medicus | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Pharmacology and Toxicology
Journal Article
Journal Article
Journal of Vascular Research, ISSN 1018-1172, 05/2017, Volume 54, Issue 3, pp. 180 - 192
Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a multifunctional neuropeptide in the VIP/secretin/glucagon peptide superfamily. Two... 
Pituitary adenylate cyclase-activating polypeptide | PACAP-KO mice | Femoral arteries | VPAC1/VPAC2 receptors | Vasoactive intestinal peptide | Carotid arteries | PAC1 receptor | Vasomotor responses | SYSTEM | CELLS | PHYSIOLOGY | VASOACTIVE-INTESTINAL-PEPTIDE | RAT | VASCULAR-RESPONSES | PHARMACOLOGICAL CHARACTERIZATION | PERIPHERAL VASCULAR DISEASE | CEREBRAL-ARTERIES | VIP | EXPRESSION | RECEPTOR-BINDING | Vasodilator Agents - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Genotype | Male | Peptide Fragments - pharmacology | Femoral Artery - drug effects | Mice, Knockout | Dose-Response Relationship, Drug | Femoral Artery - enzymology | Phenotype | Animals | Signal Transduction - drug effects | Vasoactive Intestinal Peptide - pharmacology | Carotid Artery, Common - enzymology | Receptors, Vasoactive Intestinal Polypeptide, Type I - agonists | Carotid Artery, Common - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - agonists | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - metabolism | Vasodilation - drug effects | In Vitro Techniques | Pituitary Adenylate Cyclase-Activating Polypeptide - deficiency | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 02/2018, Volume 314, Issue 2, pp. C233 - C241
Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors (Adcyap1r1) significantly increases excitability of guinea pig... 
Autonomic neuron | Src family kinases | Neuronal excitability | CELLS | ACTIVATION | DOMAIN | PHYSIOLOGY | MECHANISM | I-H | PIG INTRACARDIAC NEURONS | CELL BIOLOGY | INTERNALIZATION | autonomic neuron | PROTEIN-COUPLED RECEPTOR | MODULATION | neuronal excitability | C-SRC | Phosphorylation | Humans | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | src-Family Kinases - metabolism | Female | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - agonists | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Neurons - drug effects | Heart - innervation | Membrane Potentials - drug effects | Cell Line | Guinea Pigs | Endocytosis - drug effects | src-Family Kinases - antagonists & inhibitors | Pyrimidines - pharmacology | Animals | Calcium Signaling - drug effects | Neurons - enzymology | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | In Vitro Techniques | Heart | Polypeptides | PAC1 protein | G protein-coupled receptors | Neurons | Excitability | Extracellular signal-regulated kinase | Src protein | Neuromodulation | Ganglia | Membrane proteins | Proteins | Pituitary adenylate cyclase-activating polypeptide | Hogs | Endocytosis | Internalization | Green fluorescent protein | Endoplasmic reticulum | Heart diseases | Inositol 1,4,5-trisphosphate | Calcium (reticular) | Inositol 1,4,5-trisphosphate receptors | Index Medicus
Journal Article