X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (488) 488
Publication (117) 117
Book Review (60) 60
Book Chapter (8) 8
Conference Proceeding (2) 2
Dissertation (2) 2
Government Document (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (415) 415
animals (270) 270
pak (249) 249
humans (244) 244
biochemistry & molecular biology (216) 216
cell biology (187) 187
phosphorylation (186) 186
p21-activated kinases (184) 184
protein-serine-threonine kinases - metabolism (170) 170
p21-activated kinase (125) 125
activation (124) 124
signal transduction (108) 108
p21-activated kinases - metabolism (107) 107
mice (101) 101
enzyme activation (84) 84
cdc42 (80) 80
cell line (78) 78
protein-serine-threonine kinases - genetics (75) 75
molecular sequence data (72) 72
actin (69) 69
amino acid sequence (69) 69
proteins (67) 67
alpha-pak (65) 65
cdc42 gtp-binding protein - metabolism (64) 64
protein-kinase (64) 64
protein binding (62) 62
rac (61) 61
p21-activated kinases - genetics (55) 55
cancer (54) 54
article (50) 50
rac gtp-binding proteins - metabolism (50) 50
macromolecular substances (49) 49
cell line, tumor (48) 48
kinases (47) 47
oncology (47) 47
family (46) 46
cytoskeleton (45) 45
rats (45) 45
transfection (45) 45
cells (43) 43
rac1 gtp-binding protein - metabolism (43) 43
mutation (42) 42
rho gtpases (42) 42
actins - metabolism (41) 41
female (41) 41
protein (41) 41
biophysics (40) 40
cells, cultured (40) 40
protein structure, tertiary (40) 40
actin cytoskeleton (39) 39
gamma-pak (39) 39
kinase (38) 38
apoptosis (37) 37
identification (36) 36
rac1 (36) 36
research article (35) 35
signal transduction - physiology (35) 35
research (34) 34
adapter protein (33) 33
cytoskeleton - metabolism (32) 32
expression (32) 32
biology (31) 31
growth (31) 31
guanine nucleotide exchange factors - metabolism (31) 31
anchorage-independent growth (30) 30
binding sites (30) 30
cell cycle proteins - metabolism (30) 30
rho-gtpases (30) 30
cell movement (29) 29
phosphotransferases (29) 29
protein kinases (29) 29
protein-serine-threonine kinases - chemistry (29) 29
analysis (28) 28
cell adhesion (28) 28
migration (28) 28
binding (27) 27
cell-migration (27) 27
cos cells (27) 27
p21-activated kinases - antagonists & inhibitors (27) 27
activated protein-kinase (26) 26
cell proliferation (26) 26
male (26) 26
models, biological (26) 26
molecular-cloning (26) 26
physiological aspects (26) 26
protein-serine-threonine kinases - physiology (26) 26
rho (26) 26
cell movement - physiology (25) 25
pak, p21-activated kinase (25) 25
rho guanine nucleotide exchange factors (25) 25
biological phenomena, cell phenomena, and immunity (24) 24
g proteins (24) 24
neurosciences (24) 24
phosphatidylinositol 3-kinase (24) 24
recombinant fusion proteins - metabolism (24) 24
autophosphorylation (23) 23
cell polarity (22) 22
developmental biology (22) 22
drosophila (22) 22
recombinant proteins - metabolism (22) 22
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Structure, ISSN 0969-2126, 12/2011, Volume 19, Issue 12, pp. 1752 - 1761
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2011, Volume 286, Issue 25, pp. 22291 - 22299
Journal Article
Journal Article
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases.... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Index Medicus | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
FEBS LETTERS, ISSN 0014-5793, 03/2002, Volume 515, Issue 1-3, pp. 84 - 88
p21-activated protein kinase gamma-PAK phosphorylates prolactin (PRL) in rat pituitary secretory granules on Ser-177 and on the equivalent site, Ser-179, in... 
CELLS | ACTIVATION | prolactin | ISOFORMS | ACTIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CLEAVAGE | protein kinase | CELL BIOLOGY | DIVALENT-CATIONS | BIOPHYSICS | PROLACTIN PHOSPHORYLATION | pituitary secretory granule | ALPHA-PAK | BOVINE PROLACTIN | p21-activated protein kinase | PAK | phosphorylation | MYOSIN LIGHT-CHAIN
Journal Article
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2001, Volume 166, Issue 4, pp. 2643 - 2650
Neutrophils stimulated with fMLP or a variety of other chemoattractants that bind to serpentine receptors coupled to heterotrimeric G proteins exhibit rapid... 
INHIBITION | TYROSINE PHOSPHORYLATION | COUPLED RECEPTORS | CASCADE | GUINEA-PIG NEUTROPHILS | COMPONENT | IMMUNOLOGY | BINDING PROTEIN | ADAPTER PROTEIN | RAPID ACTIVATION | FAMILY | p21-Activated Kinases | Calcium - metabolism | Neutrophil Activation - drug effects | Type C Phospholipases - metabolism | rac GTP-Binding Proteins - metabolism | ras Proteins - metabolism | Type C Phospholipases - antagonists & inhibitors | rac GTP-Binding Proteins - antagonists & inhibitors | Calcium - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | N-Formylmethionine Leucyl-Phenylalanine - pharmacology | Intracellular Fluid - metabolism | Protein-Serine-Threonine Kinases - metabolism | Calmodulin - metabolism | Guinea Pigs | Neutrophils - enzymology | Neutrophils - drug effects | Enzyme Inhibitors - pharmacology | ras Proteins - antagonists & inhibitors | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Calcium Signaling - drug effects | Calmodulin - antagonists & inhibitors | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Mitogen-Activated Protein Kinases - metabolism | Pak protein | Index Medicus | Abridged Index Medicus
Journal Article