X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
pak4 (116) 116
index medicus (90) 90
humans (79) 79
p21-activated kinases - metabolism (64) 64
animals (45) 45
oncology (44) 44
cancer (43) 43
p21-activated kinases - genetics (40) 40
biochemistry & molecular biology (38) 38
cell line, tumor (37) 37
phosphorylation (37) 37
invasion (36) 36
cell biology (34) 34
expression (32) 32
migration (30) 30
p21-activated kinase (30) 30
anchorage-independent growth (29) 29
proliferation (29) 29
kinases (28) 28
mice (28) 28
signal transduction (28) 28
activation (27) 27
cell proliferation (25) 25
female (25) 25
cell cycle (22) 22
p21-activated kinases - antagonists & inhibitors (22) 22
apoptosis (21) 21
metastasis (21) 21
p21-activated kinase 4 (21) 21
p21-activated kinases (21) 21
growth (20) 20
proteins (18) 18
gene expression regulation, neoplastic (17) 17
male (17) 17
transfection (16) 16
analysis (15) 15
cells (15) 15
pancreatic cancer (15) 15
survival (15) 15
breast cancer (14) 14
gene expression (14) 14
research (14) 14
tumors (14) 14
article (13) 13
cell growth (13) 13
inhibitor (13) 13
serine/threonine kinase pak4 (13) 13
cell line (12) 12
cell movement (12) 12
development and progression (12) 12
enzyme activation (12) 12
neoplasm invasiveness (12) 12
poor-prognosis (12) 12
protein kinase inhibitors - pharmacology (12) 12
rna interference (12) 12
cell proliferation - drug effects (11) 11
protein (11) 11
protein binding (11) 11
serine/threonine kinase (11) 11
actin cytoskeleton (10) 10
aged (10) 10
binding (10) 10
care and treatment (10) 10
gastric cancer (10) 10
genetic aspects (10) 10
lim kinases - metabolism (10) 10
middle aged (10) 10
protein-kinase (10) 10
receptor (10) 10
resistance (10) 10
tumorigenesis (10) 10
adult (9) 9
cancer cells (9) 9
cell migration (9) 9
cell survival (9) 9
cytoskeleton (9) 9
inhibition (9) 9
mice, nude (9) 9
research paper (9) 9
actin (8) 8
akt (8) 8
antineoplastic agents - pharmacology (8) 8
beta-catenin (8) 8
cdc42 (8) 8
cell adhesion & migration (8) 8
cell-migration (8) 8
erk (8) 8
genetics & heredity (8) 8
kinase (8) 8
medical prognosis (8) 8
nf-kappa-b (8) 8
p21-activated kinases - physiology (8) 8
pathway (8) 8
protein-serine-threonine kinases - metabolism (8) 8
proto-oncogene proteins c-akt - metabolism (8) 8
signal transduction - drug effects (8) 8
signal transduction - physiology (8) 8
signaling pathway (8) 8
time factors (8) 8
up-regulation (8) 8
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


CANCER RESEARCH, ISSN 0008-5472, 11/2015, Volume 75, Issue 21, pp. 4466 - 4473
Integrin alpha v beta 3 has been implicated as a driver of aggressive and metastatic disease, and is upregulated during glioblastoma progression. Here, we... 
ONCOLOGY | GLIOMA | RESISTANCE | STEMNESS | CELLULAR SENESCENCE | EXPRESSION | CANCER | TUMORS | PAK4
Journal Article
APMIS, ISSN 0903-4641, 08/2017, Volume 125, Issue 8, pp. 699 - 707
Journal Article
Oncotarget, ISSN 1949-2553, 06/2018, Volume 9, Issue 47, pp. 28391 - 28407
Although microRNA (miR) 199a-3p functions as a tumor suppressor in multiple malignancies, its expression and role in esophageal cancer have not been studied.... 
MicroRNA | MiR-199a-3p | Esophageal cancer | PAK4
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2019, Volume 25, Issue 1, pp. 369 - 377
Purpose: p21-activated kinase 4 (PAK4) plays a significant biological and functional role in a number of malignancies, including multiple myeloma (MM). On the... 
BENDAMUSTINE | CELLS | ACTIVATION | ONCOLOGY | NAD(+) | P21-ACTIVATED KINASE 4 | DRUG-RESISTANCE | MUTATIONS | MULTIPLE | MYD88 | PAK4
Journal Article
BLOOD, ISSN 0006-4971, 05/2019, Volume 133, Issue 20, pp. 2198 - 2211
There is a growing body of evidence that the molecular properties of leukemia stem cells (LSCs) are associated with clinical outcomes in acute myeloid leukemia... 
AML | FUNCTIONAL SCREEN | ENGRAFTMENT | HEMATOPOIESIS | IN-VIVO | P21-ACTIVATED KINASE 4 | ACUTE MYELOID-LEUKEMIA | HEMATOLOGY | EXPRESSION | SIGNATURE | PAK4
Journal Article
CANCER LETTERS, ISSN 0304-3835, 2019, Volume 458, pp. 66 - 75
Despite the effectiveness of endocrine therapies to treat estrogen receptor-positive (ER +) breast tumours, two thirds of patients will eventually relapse due... 
CELLS | Endocrine resistance | ACTIVATION | PROTEIN | TAMOXIFEN RESISTANCE | Breast cancer | AMPLIFICATION | HIGH-GRADE | ONCOLOGY | ESTROGEN-RECEPTOR-ALPHA | ESR1 MUTATIONS | Cancer stem cells | EXPRESSION | TUMORIGENESIS | PAK4
Journal Article
Journal Article
世界胃肠病学杂志:英文版, ISSN 1007-9327, 2016, Issue 3, pp. 1224 - 1235
P21-activated kinases (PAKs) are central players invarious oncogenic signaling pathways. The six PAKfamily members are classified into group Ⅰ (PAK1-3)and... 
p21-activated | Group | | Signalingpathway | kinases | inhibitor | Drugtarget | cancer | Gastrointestinal | PAK4
Journal Article
Fertility and Sterility, ISSN 0015-0282, 2015, Volume 103, Issue 4, pp. 1089 - 1097.e2
Journal Article
Oncotarget, ISSN 1949-2553, 09/2017, Volume 8, Issue 40, p. 68083
Cross-talk between estrogen receptor alpha (ERα) and signal transduction pathways plays an important role in the progression of endometrial cancer (EC). Here,... 
Journal Article
by He, YT and Yang, LL and Luo, SM and Shen, W and Yin, S and Sun, QY
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, ISSN 1449-2288, 2019, Volume 15, Issue 11, pp. 2408 - 2418
Meiotic maturation of oocyte is an important process for successful fertilization, in which cytoskeletal integrality takes a significant role. The p-21... 
MIGRATION | CELLS | PF-3758309 | meiosis | cytoskeleton | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | centrosome | ESTABLISHMENT | POSITION | INVASION | oocyte | INHIBITOR | PAK4
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 02/2012, Volume 1823, Issue 2, pp. 465 - 475
The canonical Wnt/β-catenin signaling pathway plays a central role in development and cancer. The p21-activated kinase 4 (PAK4) involves in a wide range of... 
β-catenin | Signal transduction | Nucleo-cytoplasmic shuttling | PAK4 | beta-catenin | MIGRATION | ACTIVATION | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEPENDENT PROTEIN-KINASE | CELL-PROLIFERATION | IDENTIFICATION | CANCER | CELL BIOLOGY | NUCLEAR-LOCALIZATION | TRANSPORT | ANCHORAGE-INDEPENDENT GROWTH
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2019, Volume 511, Issue 2, pp. 404 - 408
Claudin-4 (CLDN4), a crucial member of tight junction proteins, is aberrantly expressed in breast cancer cells and contributes to cell migration and invasion.... 
CLDN4 | CEBPB | Breast cancer | Migration | Invasion | PAK4 | C/EBP-BETA | STATISTICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | BIOPHYSICS | POOR-PROGNOSIS | GROWTH | GRADE | CLAUDIN-4 EXPRESSION | Proteins | Metastasis | Cells | Protein binding
Journal Article