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JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 05/2019, Volume 37, Issue 13, pp. 1070 - 1070
PURPOSE To compare the risk of neoplastic progression by germline mutation status versus family history without a known germline mutation (familial risk) among... 
HEREDITARY PANCREATITIS | ONCOLOGY | BRCA2 | CANCER | PALB2 | FAMILIES
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2018, Volume 110, Issue 8, pp. 855 - 862
Background: Germline genetic testing with hereditary cancer gene panels can identify women at increased risk of breast cancer. However, those at increased risk... 
SURVIVAL | INHERITED MUTATIONS | WOMEN | REPAIR | ONCOLOGY | PHENOTYPE | CONFER SUSCEPTIBILITY | OVARIAN-CANCER | PALB2
Journal Article
Cancer, ISSN 0008-543X, 01/2017, Volume 123, Issue 2, pp. 210 - 218
Journal Article
Journal Article
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 4/2019, Volume 174, Issue 2, pp. 469 - 477
Breast cancer (BC) is the leading cause of cancer death in Caribbean women. Across the Caribbean islands, the prevalence of hereditary breast cancer among... 
Medicine & Public Health | Oncology | Trinidad and Tobago | Breast cancer | RRSO | BRCA1 | BRCA2 | RRM | PALB2 | RISK ASSESSMENT BREAST | MORTALITY | POPULATION | RACIAL-DIFFERENCES | HEREDITARY BREAST | PALB2 MUTATIONS | CARRIERS | ONCOLOGY | OVARIAN | BRCA2 MUTATION | Prevention | Women | Gene mutations | Mortality | Medical genetics | Family | Genetic screening | Cancer
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2015, Volume 33, Issue 4, pp. 304 - 311
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 03/2019, Volume 25, Issue 5, pp. 1517 - 1525
Purpose: Lung cancer is the leading cause of cancer deaths worldwide, with substantially better prognosis in early-stage as opposed to late-stage disease.... 
BREAST-CANCER | SUBTYPE | REPAIR | ONCOLOGY | UBIQUITIN LIGASE | SUSCEPTIBILITY GENE | OVARIAN | BIALLELIC MUTATIONS | PALB2 | HERITABILITY | DEFICIENCY
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 4/2019, Volume 174, Issue 2, pp. 543 - 550
Disruption of splicing motifs by genetic variants can affect the correct generation of mature mRNA molecules leading to aberrant transcripts. In some cases,... 
Alternative splicing | Oncology | RNA isoforms | Hereditary breast cancer | Medicine & Public Health | PALB2 | EX-VIVO ASSAY | VARIANTS | RNA | ONCOLOGY | DISEASE | MUTATIONS | BRCA2 | PROTEINS PALB2 | Proteins | Physiological aspects | Breast cancer | Disease susceptibility | Nucleotide sequencing | DNA sequencing
Journal Article
Lung Cancer, ISSN 0169-5002, 11/2019, Volume 137, pp. 48 - 51
Identifying new predictive biomarkers in lung cancer that will prolong survival for additional subgroups of patients is of utmost importance. We report... 
Platinum | Lung cancer | Homologous recombination | PARP | BRCA1 | BRCA2 | PALB2
Journal Article
Cancer research, ISSN 0008-5472, 7/2018, Volume 78, Issue 14, pp. 3969 - 3981
The BRCA1-PALB2-BRCA2 axis plays an essential role in DNA homologous recombination repair (HRR), defect in which drives genome instability and cancer... 
BRCA1 | NFκB | BRCA2 | thymic lymphoma | PALB2 | p53
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2018, Volume 24, Issue 20, pp. 5153 - 5164
Purpose: Introduced in 1987, platinum-based chemotherapy remains standard of care for small cell lung cancer (SCLC), a most aggressive, recalcitrant tumor.... 
IN-VITRO | CIRCULATING TUMOR-CELLS | ONCOLOGY | EX-VIVO CULTURE | DNA-DAMAGE | PHASE-II | HOMOLOGOUS RECOMBINATION | PALB2 | PRECLINICAL TESTING PROGRAM | CLINICAL-SIGNIFICANCE | BMN 673
Journal Article
Gut, ISSN 0017-5749, 03/2013, Volume 62, Issue 3, pp. 339 - 347
Journal Article