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Molecular Genetics and Metabolism, ISSN 1096-7192, 02/2016, Volume 117, Issue 2, pp. 210 - 216
Infantile neuronal ceroid lipofuscinosis (INCL, Infantile Batten disease) is an invariably fatal neurodegenerative pediatric disorder caused by an inherited... 
Palmitoyl protein thioesterase-1 | Enzyme replacement therapy | Batten disease | Histochemistry | Lysosomal storage disorder
Journal Article
by Ou, PJ and Wen, LF and Liu, XL and Huang, JC and Huang, XL and Su, CF and Wang, L and Ni, H and Reizis, B and Yang, CY
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 09/2019, Volume 216, Issue 9, pp. 2091 - 2112
Conventional type 1 dendritic cells (cDC1s) are inherently resistant to many viruses but, paradoxically, possess fewer acidic phagosomes that enable antigen... 
MHC CLASS-I | TISSUE-RESIDENT | EFFECTOR | MEDICINE, RESEARCH & EXPERIMENTAL | CD8(+) | PALMITOYL-PROTEIN THIOESTERASE | RECEPTOR | INFLUENZA-VIRUS | IMMUNOLOGY | EXPRESSION | TRANSCRIPTION FACTOR ZDC | CROSS-PRESENTATION
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 15
Neuronal ceroid lipofuscinosis (NCL) type 1 (CLN1) is a neurodegenerative storage disorder caused by mutations in the gene encoding the lysosomal enzyme... 
Enzymes | Phenotypes | Animal models | Thioesterase | Retina | Atrophy | Retinal ganglion cells | Gliosis | Neurodegeneration | Blindness | Bipolar cells | Retinal degeneration | Neuronal ceroid lipofuscinosis | Ganglion cells | Age | Palmitoyl-(protein) hydrolase | Seizures
Journal Article
by Liu, HC and Yan, PP and Ren, JY and Wu, C and Yuan, W and Rao, MD and Zhang, ZJ and Kong, EY
CURRENT MOLECULAR MEDICINE, ISSN 1566-5240, 2019, Volume 19, Issue 5, pp. 364 - 375
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 07/2009, Volume 1793, Issue 7, pp. 1250 - 1258
Induction of apoptosis by TNF has recently been shown to implicate proteases from lysosomal origin, the cathepsins. Here, we investigated the role in apoptosis... 
Neuronal ceroid lipofuscinosis | Cell death | Palmitoylation | Lysosome | Apoptosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | TNF-INDUCED APOPTOSIS | CELL-DEATH | CELL BIOLOGY | SIGNAL-TRANSDUCTION | CHOLESTEROL-METABOLISM | LIPID RAFTS | MOUSE MODEL | ACID SPHINGOMYELINASE | PALMITOYL-PROTEIN-THIOESTERASE-1 PPT1 | NEURONAL CEROID-LIPOFUSCINOSIS | CATHEPSIN-B | Neuronal Ceroid-Lipofuscinoses - enzymology | Skin - cytology | Apoptosis - drug effects | Skin - metabolism | Humans | NF-kappa B - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Neuronal Ceroid-Lipofuscinoses - pathology | Membrane Glycoproteins - physiology | Flow Cytometry | Membrane Proteins - metabolism | Fibroblasts - metabolism | Membrane Proteins - genetics | Thiolester Hydrolases - physiology | TNF-Related Apoptosis-Inducing Ligand - metabolism | Molecular Chaperones - physiology | Blotting, Western | Mice, Knockout | Tumor Necrosis Factor-alpha - pharmacology | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Transformation, Neoplastic | Fibroblasts - drug effects | Fibroblasts - cytology | Mice | Skin - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | Molecular Chaperones | Receptors, Tumor Necrosis Factor, Type I | Tumor Necrosis Factor-alpha | Membrane Proteins | NF-kappa B | TNF-Related Apoptosis-Inducing Ligand | Neuronal Ceroid-Lipofuscinoses | Fibroblasts | Thiolester Hydrolases | Skin | Membrane Glycoproteins | Mitogen-Activated Protein Kinase 1 | Mitogen-Activated Protein Kinase 3
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 09/2019, Volume 23, Issue 9, pp. 6512 - 6518
Genome‐wide association studies have confirmed that schizophrenia is an inheritable multiple‐gene mental disorder. Longitudinal studies about depression, first... 
enzymatic activity | schizophrenia | biomarker | palmitoyl‐protein thioesterase | MORTALITY | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | MICE | CARBONYL STRESS | palmitoyl-protein thioesterase | LIFE EXPECTANCY | CELL BIOLOGY | Schizophrenia | Medicine, Experimental | Enzymes | Medical research | Diagnosis | Blood proteins | Letters to the Editor | Letter to the Editor
Journal Article