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Nature, ISSN 0028-0836, 01/2018, Volume 553, Issue 7689, pp. 501 - 505
Journal Article
Circulation Research, ISSN 0009-7330, 04/2017, Volume 120, Issue 9, pp. 1466 - 1476
RATIONALE:Paracrine secretions seem to mediate therapeutic effects of human CD34 stem cells locally transplanted in patients with myocardial and critical limb... 
cell transplantation | stem cells | exosomes | hindlimb | Cardiovascular disease | microRNA | ischemia | CARDIAC-FUNCTION | PROGENITOR CELLS | CIRCULATING MICRORNAS | cardiovascular disease | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | RANDOMIZED PHASE-1 TRIAL | HEART | THERAPY | EXTRACELLULAR VESICLES | VASCULAR INTEGRITY | PERIPHERAL VASCULAR DISEASE | NEOVASCULARIZATION | HEMATOLOGY | Exosomes - metabolism | Angiogenic Proteins - genetics | Hindlimb | Antigens, CD34 - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Humans | MicroRNAs - metabolism | Ischemia - genetics | Motor Activity | Recovery of Function | Transfection | RNA Interference | Time Factors | Endothelial Progenitor Cells - transplantation | Disease Models, Animal | Endothelial Progenitor Cells - metabolism | Muscle, Skeletal - blood supply | Biomarkers - metabolism | Exosomes - transplantation | Paracrine Communication | Signal Transduction | Cells, Cultured | Gene Expression Regulation | Ischemia - metabolism | Ischemia - physiopathology | Regional Blood Flow | Phenotype | Animals | Ischemia - surgery | Mice, Inbred BALB C | MicroRNAs - genetics | Angiogenic Proteins - metabolism | Neovascularization, Physiologic | Culture Media, Conditioned - metabolism | CD34 antigen | Animal models | Angiopoietin | Secretion | MiRNA | Stem cell transplantation | Paracrine signalling | Smooth muscle | Secretions | Exosomes | Endothelial cells | Gelatinase B | Endothelium | Angiogenesis | Ischemia | Perfusion | Rodents | Amputation | Stem cells | Fibroblasts | Metalloproteinase | Vascular endothelial growth factor | Thrombospondin | Index Medicus | angiogenesis | Stem cell therapy | Cell Therapy | Stem Cells | stem cell | Cell Signaling | translational studies | CD34+ cells
Journal Article
Circulation Research, ISSN 0009-7330, 08/2013, Volume 113, Issue 5, pp. 539 - 552
RATIONALE:Autologous bone marrow–derived or cardiac-derived stem cell therapy for heart disease has demonstrated safety and efficacy in clinical trials, but... 
paracrine communication | stem cells | differentiation | myocardial infarction | neovascularization | PROGENITOR CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | COLLATERAL PERFUSION | RANDOMIZED PHASE-1 TRIAL | CARDIAC MYOCYTES | MARROW-CELLS | VENTRICULAR MYOCYTES | CARDIOMYOCYTES | TRANSPLANTATION | ISCHEMIC CARDIOMYOPATHY | IN-VIVO | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Angiogenic Proteins - genetics | Angiogenic Proteins - secretion | Cells, Cultured - cytology | Antigens, Ly - genetics | Proto-Oncogene Proteins c-kit - biosynthesis | Paracrine Communication - physiology | Antigens, Ly - biosynthesis | Multipotent Stem Cells - transplantation | Myocardial Infarction - pathology | Cell Transdifferentiation | Myocardial Infarction - physiopathology | Proto-Oncogene Proteins c-kit - genetics | Multipotent Stem Cells - physiology | Angiogenic Proteins - biosynthesis | Genes, Reporter | Bone and Bones - cytology | Multipotent Stem Cells - secretion | Myocytes, Cardiac - cytology | Membrane Proteins - genetics | Neovascularization, Physiologic - genetics | Mice, Inbred C57BL | Gene Expression Regulation | Mice, Transgenic | Ventricular Remodeling - physiology | Cells, Cultured - secretion | Membrane Proteins - biosynthesis | Animals | Endothelial Cells - cytology | Multipotent Stem Cells - cytology | Biomarkers | Mice | Index Medicus | paracrine signaling | Stem cells
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2017, Volume 23, Issue 1, pp. 91 - 99
The role of osteolineage cells in regulating hematopoietic stem cell (HSC) regeneration following myelosuppression is not well understood. Here we show that... 
MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | STEM-CELL NICHE | SELF-RENEWAL | LYMPHOID PROGENITORS | CELL BIOLOGY | MAINTENANCE | ENGRAFTMENT | DIFFERENTIATION | WNT | RECONSTITUTION | Whole-Body Irradiation | Reactive Oxygen Species | bcl-2 Homologous Antagonist-Killer Protein - genetics | Gene Expression Profiling | Cell Self Renewal | Intercellular Signaling Peptides and Proteins - metabolism | Flow Cytometry | Bone Marrow - metabolism | Hematopoietic Stem Cells - radiation effects | bcl-2-Associated X Protein - genetics | Hematopoietic Stem Cells - drug effects | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Endothelial Cells - metabolism | Hematopoietic Stem Cells - metabolism | Mitochondria - metabolism | Transcription Factors - metabolism | Regeneration | Animals | Intercellular Signaling Peptides and Proteins - pharmacology | Sp7 Transcription Factor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Osteoblasts - metabolism | Epidermal Growth Factor - secretion | Radiation Injuries, Experimental | Bone Marrow Cells - metabolism | Cellular proteins | Genetic aspects | Regeneration (Biology) | Health aspects | Hematopoietic stem cells | Reactive oxygen species | Senescence | Bax protein | Crosstalk | Radiation | Irradiated | Paracrine signalling | Proteins | Mitochondria | Biomedical materials | Epidermal growth factor | Clonal deletion | Data recovery | Rodents | Bone marrow | Deletion | Myelosuppression | Biocompatibility | Growth factors | Cell survival | Secretion | Radioprotection | Progenitor cells | Endothelial cells | Hemopoiesis | Stem cells | Cells (biology) | Irradiation | Dkk1 protein | Apoptosis | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 03/2008, Volume 294, Issue 3, pp. 675 - 682
Understanding the mechanisms by which adult stem cells produce growth factors may represent an important way to optimize their beneficial paracrine and... 
Fibroblast growth factor 2 | Mitogen-activated protein kinase | Hepatocyte growth factor | Insulin-like growth factor 1 | Vascular endothelial growth factor | PROGENITOR CELLS | KINASE PATHWAY | PHYSIOLOGY | VENTRICULAR-FUNCTION | VEGF | BONE-MARROW | TRAUMA-HEMORRHAGE | INFARCTED MYOCARDIUM | CELL BIOLOGY | mitogen-activated protein kinase | IN-VITRO | vascular endothelial growth factor | fibroblast growth factor 2 | hepatocyte growth factor | CARDIAC-SURGERY | insulin-like growth factor 1 | STROMAL CELLS | Mesenchymal Stromal Cells - enzymology | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Peptide Fragments - pharmacology | Vascular Endothelial Growth Factor A - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Cell Hypoxia | Intercellular Signaling Peptides and Proteins - metabolism | Cell Shape | Fibroblast Growth Factor 2 - metabolism | Mesenchymal Stromal Cells - drug effects | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Paracrine Communication | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Hepatocyte Growth Factor - metabolism | Signal Transduction - drug effects | Lipopolysaccharides - pharmacology | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Insulin-Like Growth Factor I - metabolism | Index Medicus
Journal Article
Pain, ISSN 0304-3959, 2011, Volume 152, Issue 9, pp. 2036 - 2051
Journal Article
Circulation, ISSN 0009-7322, 03/2004, Volume 109, Issue 12, pp. 1543 - 1549
Background - Bone marrow cell therapy is reported to contribute to collateral formation through cell incorporation into new or remodeling vessels. However, the... 
Cells, bone marrow | Angiogenesis | Cells, stromal | PROGENITOR CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | angiogenesis | cells, bone marrow | MONONUCLEAR-CELLS | ISCHEMIC MYOCARDIUM | DIFFERENTIATE | MESENCHYMAL STEM-CELLS | IN-VITRO | IMPLANTATION | cells, stromal | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | REGIONAL FUNCTION | ENDOTHELIAL GROWTH-FACTOR | Endothelium, Vascular - cytology | Growth Substances - secretion | Stromal Cells - transplantation | Chemokine CCL2 - secretion | Collateral Circulation | Cells, Cultured - transplantation | Culture Media, Conditioned - pharmacology | Endothelium, Vascular - drug effects | Hypoxia-Inducible Factor 1, alpha Subunit | Vascular Endothelial Growth Factor A - secretion | Fibroblast Growth Factor 2 - secretion | Immunomagnetic Separation | Myocytes, Smooth Muscle - drug effects | Muscular Atrophy - etiology | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Muscle, Skeletal - blood supply | Muscle, Smooth, Vascular - drug effects | Paracrine Communication | Endothelial Cells - metabolism | Muscular Atrophy - pathology | Ischemia - therapy | Transcription Factors - biosynthesis | Injections, Intramuscular | Ischemia - physiopathology | Transcription Factors - genetics | Muscle, Smooth, Vascular - cytology | Cells, Cultured - secretion | Animals | Endothelial Cells - cytology | Hindlimb - blood supply | Pregnancy Proteins - secretion | Fibrosis | Placenta Growth Factor | Mice | Mice, Inbred BALB C | Muscle, Skeletal - pathology | Mesenchymal Stem Cell Transplantation | Endothelial Cells - drug effects | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e95312 - e95312
Journal Article