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1. Full Text PTH 1-34 (teriparatide) may not improve healing in proximal humerus fractures
: A randomized, controlled study of 40 patients
by Johansson, Torsten and Region Ɩstergƶtland and Medicinska fakulteten and Linkƶpings universitet and Institutionen fƶr klinisk och experimentell medicin and Avdelningen fƶr kliniska vetenskaper and Centrum fƶr kirurgi, ortopedi och cancervĆ„rd and Ortopedkliniken i Linkƶping
Acta Orthopaedica, ISSN 1745-3674, 01/2016, Volume 87, Issue 1, pp. 79 - 82
Background and purpose - There is solid evidence from animal experiments that parathyroid hormone (PTH) improves fracture healing. So far, only 3 papers on PTH... 
SURGERY | TRIAL | WOMEN | BONE MORPHOGENETIC PROTEIN-2 | PARATHYROID-HORMONE | ORTHOPEDICS | FIXATION | Shoulder Fractures - surgery | Fracture Fixation - methods | Osteoporosis, Postmenopausal - diagnosis | Prospective Studies | Drug Administration Schedule | Follow-Up Studies | Risk Assessment | Teriparatide - administration & dosage | Humans | Middle Aged | Shoulder Fractures - drug therapy | Osteoporosis, Postmenopausal - complications | Treatment Outcome | Injury Severity Score | Dose-Response Relationship, Drug | Radiography | Fracture Healing - drug effects | Aged, 80 and over | Female | Parathyroid Hormone - administration & dosage | Aged | Shoulder Fractures - etiology | Shoulder Fractures - diagnostic imaging | Index Medicus | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hƤlsovetenskap
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2. Full Text PTH(1ā€34) effects on repairing experimentally drilled holes in rat femur: novel aspectsĀ ā€“Ā qualitative vs. quantitative improvement of osteogenesis
by Cavani, Francesco and Ferretti, Marzia and Smargiassi, Alberto and Palumbo, Carla
Journal of Anatomy, ISSN 0021-8782, 01/2017, Volume 230, Issue 1, pp. 75 - 84
The timetable of effects on bone repair of the active fractionā€parathyroid hormone, PTH (1ā€34), was analytically investigated from the morphometric viewpoint... 
rat model | PTH | collagen texture | osteoblasts | osteocytes | fracture healing | 1ā€34 | PTH(1-34) | CORTICAL BONE | ANATOMY & MORPHOLOGY | MECHANICAL-PROPERTIES | INTERMITTENT PTH | OSTEOPOROSIS | BONE-FORMATION | GENE-EXPRESSION | PARATHYROID-HORMONE | GROWTH-FACTOR | POSTMENOPAUSAL WOMEN | CELL-LINE | Bone and Bones - pathology | Osteogenesis - physiology | Bone and Bones - physiology | Femur - pathology | Osteogenesis - drug effects | Rats | Femur - drug effects | Male | Parathyroid Hormone - pharmacology | Treatment Outcome | Rats, Sprague-Dawley | Bone and Bones - drug effects | Femur - physiology | Animals | Wound Healing - physiology | Wound Healing - drug effects | Parathyroid hormone | Collagen | Index Medicus | PTH(1ā€34) | Original
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3. Full Text Transient Increased Calcium and Calcitriol Requirements After Discontinuation of Human Synthetic Parathyroid Hormone 1ā€34 (hPTH 1ā€34) Replacement Therapy in Hypoparathyroidism
by Gafni, Rachel I and Guthrie, Lori C and Kelly, Marilyn H and Brillante, Beth A and Christie, C Michele and Reynolds, James C and Yovetich, Nancy A and James, Robert and Collins, Michael T
Journal of Bone and Mineral Research, ISSN 0884-0431, 11/2015, Volume 30, Issue 11, pp. 2112 - 2118
Synthetic human PTH 1-34 (hPTH 1-34) replacement therapy in hypoparathyroidism maintains eucalcemia and converts quiescent bone to high-turnover bone. However,... 
PARATHYROIDā€RELATED DISORDERS | DXA | HORMONE REPLACEMENT | PTH | BIOCHEMICAL MARKERS OF BONE TURNOVER | PARATHYROID-RELATED DISORDERS | VITAMIN-D | PRIMARY HYPERPARATHYROIDISM | PTH(1-84) | TURNOVER | BONE-MINERAL DENSITY | OSTEOPOROSIS | SKELETON | ENDOCRINOLOGY & METABOLISM | DIFFERENTIATION | POSTMENOPAUSAL WOMEN | LONG-TERM TREATMENT | Teriparatide - therapeutic use | Humans | Middle Aged | Alkaline Phosphatase - metabolism | Calcium - administration & dosage | Male | Calcitriol - therapeutic use | Bone and Bones - drug effects | Dose-Response Relationship, Drug | Calcitriol - administration & dosage | Calcium - blood | Peptides - metabolism | Bone and Bones - metabolism | Adult | Female | Hypoparathyroidism - drug therapy | Calcium - pharmacology | Collagen Type I - metabolism | Teriparatide - pharmacology | Teriparatide - administration & dosage | Osteocalcin - metabolism | Biomarkers - blood | Withholding Treatment | Bone Density - drug effects | Calcium - therapeutic use | Calcitriol - pharmacology | Adolescent | Hypoparathyroidism - blood | Bones | Parathyroid hormone | Density | Hypoparathyroidism | Index Medicus
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4. Full Text Effects of Pump versus Twice-Daily Injection Delivery of Synthetic Parathyroid Hormone 1-34 in Children with Severe CongenitalĀ Hypoparathyroidism
by Winer, Karen K., MD and Fulton, Kara A., BS and Albert, Paul S., PhD and Cutler, Gordon B., MD
Journal of Pediatrics, The, ISSN 0022-3476, 2014, Volume 165, Issue 3, pp. 556 - 563.e1
Objective To compare the response with synthetic human parathyroid hormone (PTH) 1-34 delivered by twice-daily injection vs insulin pump in children with... 
Pediatrics | TRIAL | PHOSPHATE | PARATHYROID-HORMONE-1-34 | REPLACEMENT THERAPY | PEDIATRICS | INFUSION | LONG-TERM TREATMENT | CALCITRIOL | Severity of Illness Index | Young Adult | Hypoparathyroidism - drug therapy | Hypoparathyroidism - congenital | Infusion Pumps | Humans | Injections, Subcutaneous | Adolescent | Female | Male | Parathyroid Hormone - administration & dosage | Child | Parathyroid hormone | Hypoparathyroidism | Genetic disorders | Index Medicus | Abridged Index Medicus
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5. Full Text Effect of systemic parathyroid hormone (1-34) and a Ī²-tricalcium phosphate biomaterial on local bone formation in a critical-size rat calvarial defect model
by Yun, Jonathan I and Wikesjƶ, Ulf Me and Borke, James L and Bisch, Frederick C and Lewis, Jill E and Herold, Robert W and Swiec, Gary D and Wood, Joseph C and McPherson III, James C
Journal of Clinical Periodontology, ISSN 0303-6979, 05/2010, Volume 37, Issue 5, pp. 419 - 426
P>Objective The objective of this study was to evaluate local bone formation following systemic administration of parathyroid hormone (1-34) (PTH), a... 
Ī²-tricalcium phosphate | Guided bone regeneration | Parathyroid hormone | Tissue engineering | Rat calvaria model | beta-tricalcium phosphate | SURGERY | DRUG | parathyroid hormone | rat calvaria model | APOPTOSIS | MATRIX | tissue engineering | REGENERATION | DENTISTRY, ORAL SURGERY & MEDICINE | guided bone regeneration | MORPHOGENETIC PROTEIN-4 | Bone Regeneration - drug effects | Rats | Male | Parathyroid Hormone - pharmacology | Bone Density Conservation Agents - administration & dosage | Random Allocation | Rats, Sprague-Dawley | Bone Density Conservation Agents - pharmacology | Injections | Animals | Skull - surgery | Bone Matrix - transplantation | Parathyroid Hormone - administration & dosage | Calcium Phosphates - pharmacology | Index Medicus | Dentistry
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6. Full Text Parathyroid hormone 1-34 and skeletal anabolic action: The use of parathyroid hormone in bone formation
by Osagie-Clouard, L and Sanghani, A and Coathup, M and Briggs, T and Bostrom, M and Blunn, G
Bone and Joint Research, ISSN 2046-3758, 01/2017, Volume 6, Issue 1, pp. 14 - 21
Intermittently administered parathyroid hormone (PTH 1-34) has been shown to promote bone formation in both human and animal studies. The hormone and its... 
Anabolic | Parathyroid hormone | Bone formation | PRIMARY HYPERPARATHYROIDISM | MESENCHYMAL STEM-CELLS | OSTEOBLASTIC CELLS | CELL & TISSUE ENGINEERING | MINERAL DENSITY | RECEPTOR ACTIVATOR | PTH/PTHRP RECEPTOR | POSTMENOPAUSAL WOMEN | ORTHOPEDICS | HEMATOPOIETIC STEM | N-CADHERIN | IGF-II
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7. Full Text Parathyroid hormone-(1-34) ameliorated knee osteoarthritis in rats via autophagy
by Chen, Chung-Hwan and Ho, Mei-Ling and Chang, Ling-Hua and Kang, Lin and Lin, Yi-Shan and Lin, Sung-Yen and Wu, Shun-Cheng and Chang, Je-Ken
Journal of Applied Physiology, ISSN 8750-7587, 05/2018, Volume 124, Issue 5, pp. 1177 - 1185
Anterior cruciate ligament (ACL) tear can lead to osteoarthritis (OA). However, parathyroid hormone (PTH)-(1-34) was found to alleviate OA progression in a... 
Parathyroid hormone | Autophagy | Osteoarthritis | Anterior cruciate ligament | parathyroid hormone | APOPTOSIS | SPORT SCIENCES | ACTIVATION | PHYSIOLOGY | autophagy | osteoarthritis | RECONSTRUCTION | CARTILAGE | REDUCES EXPERIMENTAL OSTEOARTHRITIS | anterior cruciate ligament | PTH/PTHRP RECEPTOR | ARTICULAR CHONDROCYTES | GROWTH-PLATE | TERMINAL DIFFERENTIATION | Knee | TOR protein | Immunohistochemistry | Collagen (type II) | Collagens | Arthritis | Hormones | Bearing | Proteins | Cartilage | Rodents | Surgery | Aging | Joint and ligament injuries | Biocompatibility | Chondrogenesis | Parathyroid | Endocrine system | Markers | Rats | Papain | Plastic surgery | Knee (anatomy) | Rapamycin | Molecular chains | Hedgehog protein | Differentiation | Phagocytosis | Apoptosis | Cartilage diseases
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8. Full Text Differing effects of PTH 1ā€“34, PTH 1ā€“84, and zoledronic acid on bone microarchitecture and estimated strength in postmenopausal women with osteoporosis: An 18ā€month openā€labeled observational study using HRā€pQCT
by Hansen, Stinus and Hauge, Ellen M and Beck Jensen, Jensā€Erik and Brixen, Kim
Journal of Bone and Mineral Research, ISSN 0884-0431, 04/2013, Volume 28, Issue 4, pp. 736 - 745
Whereas the beneficial effects of intermittent treatment with parathyroid hormone (PTH) (intact PTH 1ā€“84 or fragment PTH 1ā€“34, teriparatide) on vertebral... 
ZOLEDRONIC ACID | PTH 1ā€“84 | HRā€PQCT | ANTIā€OSTEOPOROTIC TREATMENT | OSTEOPOROSIS | PTH 1ā€“34 | HR-PQCT | PTH 1-34 | PTH 1-84 | osteoporosis | anti-osteoporotic treatment | zoledronic acid | CORTICAL BONE | OVARIECTOMIZED RHESUS-MONKEYS | PARATHYROID-HORMONE 1-34 | TERIPARATIDE | QUANTITATIVE COMPUTED-TOMOGRAPHY | ALENDRONATE | ANTI-OSTEOPOROTIC TREATMENT | TRABECULAR BONE | MINERAL DENSITY | DISTAL RADIUS | IN-VIVO | ENDOCRINOLOGY & METABOLISM | Bone and Bones - pathology | Radius - pathology | Humans | Middle Aged | Parathyroid Hormone - therapeutic use | Osteoporosis - drug therapy | Parathyroid Hormone - pharmacology | Tomography, X-Ray Computed | Bone Remodeling - drug effects | Tibia - pathology | Bone and Bones - drug effects | Time Factors | Bone and Bones - diagnostic imaging | Osteoporosis - diagnostic imaging | Biomechanical Phenomena - drug effects | Radius - drug effects | Aged, 80 and over | Diphosphonates - therapeutic use | Postmenopause | Female | Finite Element Analysis | Imidazoles - therapeutic use | Osteoporosis - physiopathology | Tibia - physiopathology | Biomarkers - metabolism | Radius - physiopathology | Imidazoles - pharmacology | Tibia - drug effects | Absorptiometry, Photon | Bone and Bones - physiopathology | Aged | Diphosphonates - pharmacology | Index Medicus
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9. Full Text Effects of intravenous zoledronic acid plus subcutaneous teriparatide [rhPTH(1ā€“34)] in postmenopausal osteoporosis
by Cosman, Felicia and Eriksen, Erik Fink and Recknor, Chris and Miller, Paul D and GuaƱabens, NĆŗria and Kasperk, Christian and Papanastasiou, Philemon and Readie, Aimee and Rao, Hanumantha and Gasser, JĆ¼rg A and Bucciā€Rechtweg, Christina and Boonen, Steven
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2011, Volume 26, Issue 3, pp. 503 - 511
Clinical data suggest concomitant therapy with bisphosphonates and parathyroid hormone (PTH) may blunt the anabolic effect of PTH; rodent models suggest that... 
ZOLEDRONIC ACID | INFUSION | TERIPARATIDE | BISPHOSPHONATE | OSTEOPOROSIS | Bisphosphonate | teriparatide | infusion | osteoporosis | zoledronic acid | BONE-MINERAL DENSITY | PARATHYROID-HORMONE 1-34 | ALENDRONATE | WOMEN | FRACTURE | BISPHOSPHONATES | THERAPY | CANCELLOUS BONE | MASS | ENDOCRINOLOGY & METABOLISM | PROXIMAL FEMUR | Collagen Type I - blood | Peptides - blood | Injections, Intravenous | Teriparatide - therapeutic use | Bone Density - physiology | Follow-Up Studies | Humans | Middle Aged | Osteoporosis, Postmenopausal - complications | Imidazoles - administration & dosage | Osteoporotic Fractures - drug therapy | Bone Remodeling - physiology | Injections, Subcutaneous | Peptide Fragments - blood | Diphosphonates - therapeutic use | Female | Imidazoles - therapeutic use | Drug Therapy, Combination | Osteoporotic Fractures - physiopathology | Diphosphonates - adverse effects | Biomarkers - metabolism | Bone Density Conservation Agents - adverse effects | Teriparatide - administration & dosage | Imidazoles - adverse effects | Bone Density Conservation Agents - therapeutic use | Diphosphonates - administration & dosage | Procollagen - blood | Bone Density Conservation Agents - administration & dosage | Osteoporosis, Postmenopausal - drug therapy | Osteoporosis, Postmenopausal - blood | Osteoporotic Fractures - complications | Least-Squares Analysis | Osteoporosis, Postmenopausal - physiopathology | Teriparatide - adverse effects | Aged | Osteoporotic Fractures - blood | Index Medicus
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10. Full Text Parathyroid hormone [1-34] improves articular cartilage surface architecture and integration and subchondral bone reconstitution in osteochondral defects inĀ vivo
by Orth, P and Cucchiarini, M and Zurakowski, D and Menger, M.D and Kohn, D.M and Madry, H
Osteoarthritis and Cartilage, ISSN 1063-4584, 2013, Volume 21, Issue 4, pp. 614 - 624
Summary Objective The 1-34 amino acid segment of the parathyroid hormone (PTH [1-34]) mediates anabolic effects in chondrocytes and osteocytes. The aim of this... 
Rheumatology | Cartilage repair | PTH1R | PTH [1-34] | Subchondral bone | Osteochondral defect | KNEE | IGF-I | AUTOLOGOUS CHONDROCYTE IMPLANTATION | PTH | RHEUMATOLOGY | OSTEOPOROSIS | EXPERIMENTAL-MODEL | FULL-THICKNESS DEFECTS | CELL-BASED REPAIR | RABBIT | OSTEOARTHRITIS | ORTHOPEDICS | Bone Regeneration - physiology | Receptor, Parathyroid Hormone, Type 1 - metabolism | Apoptosis - drug effects | Calcium - metabolism | Parathyroid Hormone - therapeutic use | Synovial Membrane - pathology | Synovial Membrane - drug effects | Femur - diagnostic imaging | Cartilage, Articular - metabolism | Female | Wound Healing - drug effects | Chondrocytes - metabolism | Femur - injuries | Bone Regeneration - drug effects | Chondrocytes - pathology | Drug Evaluation, Preclinical - methods | Rabbits | Osteocytes - metabolism | Femur - metabolism | Injections, Intramuscular | Femur - physiopathology | X-Ray Microtomography - methods | Cartilage, Articular - pathology | Collagen - metabolism | Animals | Cartilage, Articular - injuries | Osteocytes - pathology | Parathyroid Hormone - administration & dosage | Wound Healing - physiology | Cartilage, Articular - drug effects | Architecture | Parathyroid hormone | Osteoarthritis | Index Medicus
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11. Full Text Synthetic Human Parathyroid Hormone 1-34 Replacement Therapy: A Randomized Crossover Trial Comparing Pump Versus Injections in the Treatment of Chronic Hypoparathyroidism
by Winer, Karen K and Zhang, Bo and Shrader, Joseph A and Peterson, Donna and Smith, Michaele and Albert, Paul S and Cutler, Gordon B
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 02/2012, Volume 97, Issue 2, pp. 391 - 399
Context: Vitamin D therapy for hypoparathyroidism does not restore PTH-dependent renal calcium reabsorption, which can lead to renal damage. An alternative... 
VITAMIN-D | HYPOCALCEMIC HYPERCALCIURIA | CANCER-PATIENTS | PARATHYROID-HORMONE-1-34 | FATIGUE SYMPTOM INVENTORY | CALCIUM | ENDOCRINOLOGY & METABOLISM | LONG-TERM TREATMENT | DIHYDROTACHYSTEROL THERAPY | HUMAN PTH(1-34) | CALCITRIOL | Hypoparathyroidism - drug therapy | Drug Administration Schedule | Infusion Pumps | Humans | Middle Aged | Postoperative Complications - blood | Male | Parathyroid Hormone - chemical synthesis | Vitamin D - blood | Cross-Over Studies | Phosphorus - blood | Injections, Subcutaneous | Hypoparathyroidism - blood | Adult | Female | Hormone Replacement Therapy - methods | Insulin Infusion Systems | Parathyroid Hormone - administration & dosage | Postoperative Complications - drug therapy | Magnesium - blood | Hypoparathyroidism - etiology | Index Medicus | Abridged Index Medicus | 2 | Endocrine Care
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12. Full Text Long-Term Parathyroid Hormone 1-34 Replacement Therapy in Children with Hypoparathyroidism
by Winer, Karen K and Kelly, Andrea and Johns, Alicia and Zhang, Bo and Dowdy, Karen and Kim, Lauren and Reynolds, James C and Albert, Paul S and Cutler, Gordon B
The Journal of Pediatrics, ISSN 0022-3476, 12/2018, Volume 203, pp. 391 - 399.e1
To determine whether multiple daily injections of parathyroid hormoneĀ (PTH) 1-34 are safe and effective as long-term therapy for children with... 
APS-1 | Vitamin D | hypocalcemia | ADH | hypomagnesemia | PTH 1-34 | teriparatide | calcium receptor | APECED | autosomal dominant hypocalcemia | PTH(1-84) | SYNDROME TYPE-I | MANAGEMENT | PARATHYROID-HORMONE-1-34 | EFFICACY | CALCIUM | MUTATION | PEDIATRICS | BONE | RANDOMIZED CROSSOVER TRIAL | CALCITRIOL | Humans | Homeostasis | Parathyroid Hormone - therapeutic use | Male | Hormone Replacement Therapy | Kidney Function Tests | Calcium - blood | Nephrocalcinosis - metabolism | DNA Mutational Analysis | Female | Polyendocrinopathies, Autoimmune - genetics | Child | Hypoparathyroidism - drug therapy | Linear Models | Treatment Outcome | Calcium - urine | Creatinine - urine | Vitamin D - blood | Body Height - drug effects | Phosphorus - urine | Calcinosis | Phosphorus - blood | Adolescent | Parathyroid Hormone - administration & dosage | Receptors, Calcium-Sensing - genetics | Phosphatases | Parathyroid hormone | Hypoparathyroidism | Bones | Calcifediol | Children | Alfacalcidol | Health aspects | Density | Index Medicus | Abridged Index Medicus
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