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British journal of pharmacology, ISSN 0007-1188, 05/2012, Volume 166, Issue 2, pp. 617 - 636
PARP | GaQ | ROS | p53
Journal Article
Journal of cellular physiology, ISSN 0021-9541, 12/2017, Volume 232, Issue 12, pp. 3744 - 3761
Strategies to treat cachexia are still at its infancy. Enhanced muscle protein breakdown and ubiquitin‐proteasome system are common features of cachexia... 
muscle atrophy and myosin loss | muscle anabolism and catabolism and mitochondrial content | PARP activity | Parp‐1−/− and Parp‐2−/− mice | cancer‐induced cachexia | Parp-1 | cancer-induced cachexia | and Parp-2 | mice | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Diaphragm - pathology | Oxidative Stress | Mitochondria, Muscle - metabolism | Lung Neoplasms - pathology | NF-kappa B - metabolism | Mice, 129 Strain | Ubiquitination | Time Factors | Proteolysis | Cachexia - etiology | Muscle Proteins - metabolism | Poly (ADP-Ribose) Polymerase-1 - deficiency | Female | Biomarkers - metabolism | Lung Neoplasms - genetics | Muscle, Skeletal - enzymology | Cachexia - genetics | Lung Neoplasms - enzymology | Signal Transduction | Mitochondria, Muscle - pathology | Mice, Inbred C57BL | Organ Size | Genotype | Poly (ADP-Ribose) Polymerase-1 - metabolism | Diaphragm - enzymology | Lung Neoplasms - complications | Mice, Knockout | Phenotype | Poly(ADP-ribose) Polymerases - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | Cachexia - enzymology | Cachexia - pathology | Muscle Fibers, Skeletal - pathology | Cell Line, Tumor | Poly(ADP-ribose) Polymerases - deficiency | Mice, Inbred BALB C | Muscle, Skeletal - pathology | Proteasome Endopeptidase Complex - metabolism | Poly (ADP-Ribose) Polymerase-1 - genetics | Apoptosis | Muscle Fibers, Skeletal - enzymology | Ubiquitin | Tyrosine | Oxidative stress | Lung cancer | Cachexia | Mitochondrial DNA | Muscle proteins | Monosaccharides | Ligases | Myosin | Genetic aspects | Sugars | Adenocarcinoma | Chromatin | Poly(ADP-ribose) | AKT protein | Nuclei | Body composition | Fibers | Proteins | Degradation | Atrophy | Genotype & phenotype | Signal transduction | Protein composition | Body composition (biology) | Ribose | Rodents | Diaphragm (anatomy) | Oxidation | Polymers | Deoxyribonucleic acid--DNA | NF-κB protein | Markers | Muscles | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Inflammation | Metabolism | Muscle contraction | Chronic conditions | Poly(ADP-ribose) Polymerase 1 | Proteasomes | Catabolism | Nuclei (cytology) | Mice | Diaphragm | Cancer | Index Medicus | 62D05 Sampling theory, sample surveys | 92D Genetics and population dynamics | 62H Multivariate analysis | 92 Biology and other natural sciences | Anàlisi multivariable | Matemàtica aplicada a les ciències | Classificació AMS | Multivariate analysis | Parp-1-/- and Parp-2-/- mice | Anàlisi numèrica | Genètica | Sampling (Statistics) | Mostreig (Estadística) | Matemàtiques i estadística | Genetics | Probabilitat | 62 Statistics | Àrees temàtiques de la UPC
Journal Article
Cancers, ISSN 2072-6694, 03/2017, Volume 9, Issue 3, p. 21
Androgen receptor (AR, a member of the steroid hormone receptor family) status has become increasingly important as both a prognostic marker and potential... 
AR/PARP interplay | Breast cancer | AR/BET interplay | AR signaling | Life Sciences & Biomedicine | Oncology | Science & Technology | Studies | Androgens | Gene expression | Medical prognosis | Estrogen | breast cancer
Journal Article
Cancer discovery, ISSN 2159-8290, 06/2019, Volume 9, Issue 6, pp. 722 - 737
Combinatorial clinical trials of PARP inhibitors with immunotherapies are ongoing, yet the immunomodulatory effects of PARP inhibition have been incompletely... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus | BRCA-associated breast cancer | CD8+ T cells | STING pathway | Type I interferon response | PARP inhibitor
Journal Article
Cancer treatment reviews, ISSN 0305-7372, 02/2019, Volume 73, pp. 1 - 9
•Ovarian cancer is the most lethal gynecologic malignancy.•PARP inhibitors are effective therapeutic agents by inducing synthetic lethality.•FDA and EMA... 
Niraparib | Olaparib | Rucaparib | PARP inhibitors | Ovarian cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Medical colleges | Drug approval | Sugars | Monosaccharides | Index Medicus
Journal Article
Journal Article