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Journal Article
Genes and Development, ISSN 0890-9369, 06/2014, Volume 28, Issue 12, pp. 1337 - 1350
Journal Article
Oncogene, ISSN 0950-9232, 02/2012, Volume 31, Issue 8, pp. 966 - 977
PAX5 encodes a master regulator of B-cell development. It fuses to other genes associated with acute lymphoblastoid leukemia (ALL). These fusion products are... 
PAX5 fusions | multimerization | DNA binding | DECREASED MOBILITY | RAR | CHROMATIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTRANUCLEAR MOBILITY | CELL BIOLOGY | PAIRED DOMAIN | ONCOLOGY | UNBALANCED TRANSLOCATIONS | GENETICS & HEREDITY | PROTEINS | BINDING | HISTONE DEACETYLASE | ACUTE PROMYELOCYTIC LEUKEMIA | PAX5 Transcription Factor - chemistry | Cell Line | Chromatin - metabolism | Gene Expression | Oncogene Proteins, Fusion - metabolism | Luciferases, Renilla - genetics | Fluorescence Recovery After Photobleaching | DNA, Circular - chemistry | Humans | Protein Multimerization | PAX5 Transcription Factor - genetics | Luciferases, Renilla - biosynthesis | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Proteins - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Polydeoxyribonucleotides - chemistry | Proteins - metabolism | Genes, Dominant | Oncogene Proteins, Fusion - genetics | Protein Binding | Protein Interaction Domains and Motifs | Proteins - chemistry | Genes, Reporter | PAX5 Transcription Factor - metabolism | Physiological aspects | Chromatin | Genetic aspects | Acute lymphocytic leukemia | Research | B cells | Oncology | Lymphocytes | Leukemia | Binding sites | Competition | Transcription factors | Nucleotide sequence | Oligonucleotides | C-Terminus | Pax5 protein | Fluorescence recovery after photobleaching | Lymphocytes B | Differentiation | Fusion protein | Cancer | multimerization stable
Journal Article
Genes and Development, ISSN 0890-9369, 02/2004, Volume 18, Issue 4, pp. 411 - 422
Journal Article
The EMBO Journal, ISSN 0261-4189, 03/2017, Volume 36, Issue 6, pp. 718 - 735
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2017, Volume 199, Issue 10, pp. 3504 - 3515
Journal Article
Immunity, ISSN 1074-7613, 07/2013, Volume 39, Issue 1, pp. 136 - 147
Journal Article
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 479 - 483
B-lymphoid transcription factors, such as PAX5 and IKZF1, are critical for early B-cell development(1,2), yet lesions of the genes encoding these transcription... 
ENERGY STRESS | ACTIVATION | GENE | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOPOIETIC STEM-CELLS | REGULATORY NETWORK | DIFFERENTIATION | MINIMAL RESIDUAL DISEASE | EXPRESSION | Glucocorticoids - therapeutic use | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Receptor, Cannabinoid, CB2 - agonists | Humans | Gene Expression Regulation, Neoplastic | Receptors, Glucocorticoid - metabolism | PAX5 Transcription Factor - deficiency | Carrier Proteins - agonists | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Chromatin Immunoprecipitation | Adenosine Triphosphate - metabolism | Cell Death | Pyruvic Acid - metabolism | Female | Ikaros Transcription Factor - metabolism | Energy Metabolism - genetics | B-Lymphocytes - metabolism | PAX5 Transcription Factor - metabolism | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | AMP-Activated Protein Kinases - antagonists & inhibitors | Carcinogenesis - genetics | PAX5 Transcription Factor - genetics | Mice, Transgenic | Citric Acid Cycle | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Transcription Factors - metabolism | B-Lymphocytes - drug effects | Receptor, Cannabinoid, CB2 - metabolism | Animals | Carrier Proteins - metabolism | Sequence Analysis, RNA | Glucocorticoids - pharmacology | Glucose - metabolism | Mice | Physiological aspects | Transcription factors | B cells | Proteins | Metabolites | Rodents | Cloning | Leukemia | Glucose | Kinases | Metabolism | Gene expression | Apoptosis
Journal Article
Oncogene, ISSN 0950-9232, 07/2012, Volume 31, Issue 29, pp. 3419 - 3430
Using genome-wide methylation screening, we identified that paired box gene 5 (PAX5) is involved in human cancer development. However, the function of PAX5 in... 
gastric cancer | epigenetic alteration | prognosis | paired box gene 5 | tumor suppressor gene | CPG ISLAND METHYLATION | CELL-DEVELOPMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEPATOCYTE GROWTH-FACTOR | DOWN-REGULATION | CELL BIOLOGY | BREAST-CANCER | MATRIX METALLOPROTEINASES | LUNG-CANCER | MET PROTOONCOGENE | ONCOLOGY | B-LYMPHOPOIESIS | GENETICS & HEREDITY | TRANSCRIPTION FACTOR BSAP | Cell Proliferation | Prognosis | Biomarkers, Tumor - deficiency | Humans | Middle Aged | Apoptosis - genetics | Male | Stomach Neoplasms - pathology | Promoter Regions, Genetic - genetics | Cell Movement - genetics | Tumor Suppressor Protein p53 - genetics | Gene Knockdown Techniques | PAX5 Transcription Factor - deficiency | Biomarkers, Tumor - metabolism | Cell Cycle Checkpoints - genetics | Female | Genes, Tumor Suppressor | PAX5 Transcription Factor - metabolism | Stomach Neoplasms - genetics | Stomach Neoplasms - diagnosis | Gene Silencing | PAX5 Transcription Factor - genetics | Up-Regulation - genetics | DNA Methylation - genetics | Animals | Survival Analysis | Cell Line, Tumor | Biomarkers, Tumor - genetics | Mice | Neoplasm Invasiveness - genetics | Epigenetic inheritance | Cell lines | Physiological aspects | Tumor suppressor genes | Genetic aspects | Research | Gene expression | Stomach cancer | Epigenetics | Gastrointestinal diseases | Medical prognosis | Cancer | Index Medicus | Animal models | Immunoprecipitation | RNA | Matrix metalloproteinase | Guanylate cyclase | Pax5 protein | Carcinogenesis | epigenetics | Metastases | c-Met protein | Demethylation | Cell cycle | DNA methylation | Gastric cancer | Colonies | Therapeutic applications | Tumorigenicity | Regression analysis | Survival | Promoters | p53 protein | cyclin D1 | X protein | Cell migration | Apoptosis | Tumors
Journal Article