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PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e103740
Alterations in gut microbiome composition have an emerging role in health and disease including brain function and behavior. Short chain fatty acids (SCFA)... 
NEURODEVELOPMENTAL DISORDERS | HISTONE-DEACETYLASE | MESSENGER-RNA | TYROSINE-HYDROXYLASE GENE | CHAIN FATTY-ACIDS | MULTIDISCIPLINARY SCIENCES | GLUTATHIONE REDOX IMBALANCE | VALPROIC ACID | GUT MICROBIOTA | RAT DISTAL COLON | RODENT MODEL | PC12 Cells - microbiology | Propionates - metabolism | Transcriptional Activation | Gene Expression Regulation | Rats | Gene Regulatory Networks | Synaptic Transmission | Host-Pathogen Interactions | Tyrosine 3-Monooxygenase - genetics | Animals | Butyric Acid - metabolism | Child Development Disorders, Pervasive - microbiology | PC12 Cells - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Enterobacteriaceae - physiology | Brain | Pediatrics | Oxidative stress | Histone deacetylase | Neurosciences | Animal models | Oxidative metabolism | Disorders | Microbiomes | Nervous system | Systematic review | Neurodevelopmental disorders | Butyric acid | Cell adhesion molecules | Mitochondria | Microbiota | Alterations | Microorganisms | Reporter gene | Metabolites | Developmental stages | Rodents | Transcription activation | Cell adhesion | Physiology | Lipid metabolism | Digestive tract | Tyrosine | Digestive system | Hydroxylase | Catecholamines | Metabolism | Cyclic AMP response element-binding protein | Gene expression | Fermentation | Patients | Fatty acids | Children & youth | Autism | Brain research | Antibiotics | Plasmids | Pheochromocytoma cells | Biomarkers | Psychiatry | Neurotransmission
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 12/2012, Volume 31, Issue 50, pp. 5193 - 5200
Neuroblastoma is a neural crest-derived embryonal tumour of the postganglionic sympathetic nervous system and a disease with several different chromosomal... 
ALK | neuroblastoma | transcription factor | MYCN | anaplastic lymphoma kinase | PROTEIN | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | CELL BIOLOGY | LUNG-CANCER | ONCOLOGY | C-MET | GENETICS & HEREDITY | N-MYC | CRIZOTINIB | INHIBITOR | EXPRESSION | ACTIVATING MUTATIONS | NIH 3T3 Cells | Oncogene Proteins - genetics | Transcription, Genetic - drug effects | Humans | Promoter Regions, Genetic - drug effects | RNA, Messenger - metabolism | PC12 Cells | Cell Transformation, Neoplastic - genetics | N-Myc Proto-Oncogene Protein | Protein Biosynthesis - genetics | Nuclear Proteins - genetics | Neuroblastoma - pathology | Neuroblastoma - genetics | RNA, Messenger - genetics | Oncogene Proteins - metabolism | Rats | Nuclear Proteins - metabolism | Down-Regulation - drug effects | Mutation - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Cell Transformation, Neoplastic - metabolism | Cycloheximide - pharmacology | Down-Regulation - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Neuroblastoma - drug therapy | Cell Line, Tumor | Protein Biosynthesis - drug effects | Cell Proliferation - drug effects | Mice | Neuroblastoma - metabolism | Cell Transformation, Neoplastic - drug effects | Complications and side effects | Gene mutations | Cancer cells | Development and progression | Genetic aspects | Lymphomas | Neuroblastoma | Research | Health aspects | Phosphotransferases | Oncology | Nervous system | Kinases | Apoptosis | Basic Medicine | Medical Biotechnology | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Medicinsk bioteknologi | Cell and Molecular Biology | Cell- och molekylärbiologi | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci)
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2011, Volume 440, Issue 3, pp. 405 - 413
Mutations in the kinase domain of ALK (anaplastic lymphoma kinase) have recently been shown to be important for the progression of the childhood tumour... 
Crizotinib | NVP-TAE684 | Gain-of-function mutation | Neuroblastoma | Anaplastic lymphoma kinase (ALK) | Cancer | DOMAIN | gain-of-function mutation | BIOCHEMISTRY & MOLECULAR BIOLOGY | anaplastic lymphoma kinase (ALK) | neuroblastoma | RTK | PF-2341066 | IDENTIFICATION | ANAPLASTIC LYMPHOMA KINASE | GENE | C-MET | cancer | DIFFERENTIATION | RECEPTOR TYROSINE KINASE | Phosphorylation | Cell Proliferation | Humans | Compound Eye, Arthropod - abnormalities | Compound Eye, Arthropod - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | Mutation, Missense | Drosophila melanogaster - genetics | PC12 Cells | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Neurites - drug effects | STAT3 Transcription Factor - metabolism | Pyrazoles - pharmacology | Animals, Genetically Modified | Neuroblastoma - genetics | Rats | Pyrimidines - pharmacology | Receptor Protein-Tyrosine Kinases - metabolism | Drosophila melanogaster - drug effects | Phenotype | Animals | Receptor Protein-Tyrosine Kinases - genetics | Cell Transformation, Neoplastic | Neuroblastoma - drug therapy | Mice | Pyridines - pharmacology | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Cell and Molecular Biology | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medical Biotechnology | Medicinska och farmaceutiska grundvetenskaper | Cell- och molekylärbiologi
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 09/2017, Volume 60, pp. 220 - 231
Journal Article
DMM Disease Models and Mechanisms, ISSN 1754-8403, 09/2016, Volume 9, Issue 9, pp. 941 - 952
The first-in-class inhibitor of ALK, c-MET and ROS1, crizotinib (Xalkori), has shown remarkable clinical efficacy in treatment of ALK-positive non-small cell... 
ALK | MYCN | Neuroblastoma | Lorlatinib | Mouse models | PF-06463922 | ACTIVATION | FUSION | PATHOLOGY | REARRANGEMENTS | ALK/ROS1 INHIBITOR | CELL BIOLOGY | ANAPLASTIC LYMPHOMA KINASE | LUNG-CANCER | GENE | CRIZOTINIB RESISTANCE | MUTATIONS | RECEPTOR TYROSINE KINASE | Pyrazoles - therapeutic use | PC12 Cells | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | N-Myc Proto-Oncogene Protein - antagonists & inhibitors | Lactams, Macrocyclic - therapeutic use | Neuroblastoma - pathology | Pyrazoles - pharmacology | Pyridines - therapeutic use | Rats | Clinical Trials as Topic | Lactams, Macrocyclic - pharmacology | Mutation - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Xenograft Model Antitumor Assays | Animals | Receptor Protein-Tyrosine Kinases - genetics | Mice, Nude | N-Myc Proto-Oncogene Protein - metabolism | Protein Kinase Inhibitors - therapeutic use | Neuroblastoma - drug therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | 304 | Medical Biotechnology | Medical and Health Sciences | Medicin och hälsovetenskap | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medicinsk bioteknologi
Journal Article
Microbial Pathogenesis, ISSN 0882-4010, 2004, Volume 37, Issue 2, pp. 73 - 85
Experimental infection of BALB/c mice with the Gram-positive bacterium Nocardia asteroides (strain GUH-2) results in life-long movement abnormalities including... 
Ammonia | Toxin | Bacteria | Nocardia | Dopamine | Parkinson's disease | MYCOBACTERIUM-TUBERCULOSIS | APOPTOSIS | ACID | bacteria | ammonia | MICROBIOLOGY | INDUCTION | IMMUNOLOGY | IN-VITRO | toxin | TREATMENT STRATEGIES | GROWTH | BRAIN-ABSCESS | INHIBITORS | dopamine | PARKINSONS-DISEASE | PC12 Cells - microbiology | Nocardia asteroides - enzymology | Animals | Culture Media | Rats | Nocardia asteroides - metabolism | Mice | Mice, Inbred BALB C | Dopamine - metabolism
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2010, Volume 398, Issue 2, pp. 351 - 361
The normal function of equine lysozyme (EL) is the hydrolysis of peptidoglycan residues of bacterial cell walls. EL is closely related to α-lactalbumins with... 
supported lipid bilayers | confocal scanning laser microscopy | equine lysozyme | oleic acid | quartz crystal microbalance with dissipation | Equine lysozyme | Quartz crystal microbalance with dissipation | Confocal scanning laser microscopy | Oleic acid | Supported lipid bilayers | APOPTOSIS | STATES | PROTEIN | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | OLEIC-ACID | QUARTZ-CRYSTAL MICROBALANCE | TUMOR-CELLS | ALPHA-LACTALBUMIN | BINDING | STRUCTURAL CHARACTERIZATION | Animals | Muramidase - chemistry | Horses | Nuclear Magnetic Resonance, Biomolecular | Phospholipids - chemistry | Rats | Unilamellar Liposomes - chemistry | Amyloid - chemistry | Lipid Bilayers - chemistry | Quartz - chemistry | PC12 Cells | Oleic Acid - chemistry | Hydrolysis | Monounsaturated fatty acids | Milk proteins | Albumin | Fluorescence | Esters | Phospholipids | Permeability | Universities and colleges | Lysozyme | Tumors | Bovine serum albumin | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | MEDICINE | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medical Biotechnology | MEDICIN | confocal laser scanning microscopy
Journal Article
Cell death & disease, ISSN 2041-4889, 2015, Volume 6, Issue 3, pp. e1683 - e1683
Journal Article
Journal of Microbiology and Biotechnology, ISSN 1017-7825, 06/2017, Volume 27, Issue 6, pp. 1090 - 1097
Journal Article
FEMS MICROBIOLOGY LETTERS, ISSN 0378-1097, 03/2010, Volume 304, Issue 1, pp. 62 - 68
Mycoplasmas often contaminate cultured cells, leading to alterations in cellular gene expression, protein synthesis, signal transduction and metabolic... 
SYSTEM | calpustatin | BETA-PEPTIDE TOXICITY | ACTIVATION | human cell cultures | INVOLVEMENT | CONTAMINATION | MICROBIOLOGY | OVEREXPRESSION | calpain-promoted proteolysis | DIFFERENTIATED PC12 CELLS | CASPASE | mycoplasma-host cell interaction | CULTURES | ASSOCIATION | Protein biosynthesis | Calpain | Cell research | Molecular genetics | Gene expression | Proteolysis | Apoptosis
Journal Article