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Cell Death and Disease, 2014, Volume 5, Issue 4, p. e1186
  Fatty and fibrous connective tissue formation is a hallmark of diseased skeletal muscle and deteriorates muscle function. We previously identified... 
PDGFRα | Mesenchymal progenitors | Human muscle | Fibrosis | Adipogenesis
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 5/2014, Volume 20, Issue 10, pp. 2740 - 2750
Journal Article
Human reproduction (Oxford, England), ISSN 0268-1161, 09/2019, Volume 34, Issue 9, pp. 1621 - 1631
Is it possible to differentiate primary human testicular platelet-derived growth factor receptor alpha positive (PDGFRα+) cells into functional Leydig cells?... 
Andrology | PDGFRα | stem Leydig cell | steroidogenesis | testis | mesenchymal stromal cell | Original
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 182, p. 111663
Receptor tyrosine kinase PDGFRα is often constitutively activated in various tumours and is regarded as a drug target. Here, we present a collection of... 
PDGFRα | Acute myeloid leukaemia | Eosinophilic leukaemia | Kinase inhibitor
Journal Article
Genesis, ISSN 1526-954X, 05/2015, Volume 53, Issue 5, pp. 329 - 336
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2015, Volume 92, Issue 4
ABSTRACT Growing evidence suggests important roles for specialized platelet-derived growth factor receptor alpha-positive (PDGFRalpha+) cells in regulating the... 
PDGFRα+ cells | fibroblast-like cells | interstitial cells
Journal Article
Cell Reports, ISSN 2211-1247, 10/2018, Volume 25, Issue 4, pp. 1002 - 1017.e4
Adipocytes arise from the commitment and differentiation of adipose precursors in white adipose tissue (WAT). In studying adipogenesis, precursor markers,... 
PDGFRα | Sox9 | Meis1 | adipocyte differentiation | Pref-1 | adipose precursors
Journal Article
Journal Article
Clinical Lung Cancer, ISSN 1525-7304, 05/2019, Volume 20, Issue 3, pp. e362 - e368
Platinum doublet chemotherapy has represented the standard of care in advanced non–small-cell lung cancer for decades. Targeting platelet-derived growth factor... 
PDGFRα | Chemotherapy | NSCLC | Receptor targeted therapies | GROWTH-FACTOR RECEPTOR | INHIBITION | ONCOLOGY | PDGFR alpha
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2019, Volume 18, Issue 10, pp. 1095 - 1109
We have previously found that Sirt2 enhanced the outgrowth of cellular processes and MBP expression in CG4 cells, where Sirt2 expression is suppressed by... 
PDGFRα | Sirt2 | differentiation | oligodendrocyte | MIGRATION | GROWTH-FACTOR-RECEPTOR | MULTIPLE-SCLEROSIS | DEMYELINATION | PDGFR alpha | NKX2.2 | GLIA | OLIGODENDROCYTE PROGENITOR CELLS | CELL BIOLOGY
Journal Article
Oncotarget, ISSN 1949-2553, 12/2017, Volume 8, Issue 65, p. 109836
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal malignancies of the gastrointestinal tract. Most GISTs harbor a c-KIT (80%) or a PDGFRα (10%)... 
Journal Article
Chinese Journal of Cancer, ISSN 1000-467X, 2011, Volume 30, Issue 9, pp. 590 - 602
Journal Article
European Journal of Cancer, ISSN 0959-8049, 03/2018, Volume 92, pp. 33 - 39
Recent randomised phase II trial data have indicated that the addition of olaratumab, a novel monoclonal antibody against platelet-derived growth factor... 
Soft tissue sarcoma | PDGFRα | Olaratumab | Therapeutic antibody | Doxorubicin | ADVANCED SOLID TUMORS | GROWTH-FACTOR-RECEPTOR | ALPHA | MONOCLONAL-ANTIBODY | OPEN-LABEL | CANCER | ONCOLOGY | PDGFR alpha | THERAPEUTIC TARGET | PHASE-3 TRIAL
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2019, Volume 510, Issue 4, pp. 489 - 494
Transcription of the platelet-derived growth factor receptor α ( ) gene is considered to be precisely regulated. We have previously reported that the gene is... 
PDGFRα | Multiple promoters | Transcriptional regulation | Genomic structure | Multiple first exons | TRANSCRIPTION FACTORS | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOPHYSICS | TESTIS | PDGFR alpha | PDGFR-ALPHA | DIFFERENTIATION | SOX9 | SRY | EXPRESSION
Journal Article
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