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Phi Delta Kappan, ISSN 0031-7217, 2/2019, Volume 100, Issue 5, pp. 79 - 79
More than 60 participants took part in PDK’s first-ever Virtual Town Hall. PDK member profiles are being upgraded, and members are asked to log in to update... 
virtual town hall | PDK membership | Phi Delta Kappan | PDK
Journal Article
PHI DELTA KAPPAN, ISSN 0031-7217, 09/2019, Volume 101, Issue 1, pp. 4 - 4
The 2019 PDK Poll suggests that it's not just ordinary Americans who no longer see teaching as a promising career. Teachers themselves would not recommend... 
PDK poll | EDUCATION & EDUCATIONAL RESEARCH | teaching | teacher shortage
Journal Article
Journal Article
Phi Delta Kappan, ISSN 0031-7217, 11/2017, Volume 99, Issue 3, pp. 79 - 79
PDK is launching the American Voice Campaign to raise funds to support the work of the PDK Poll of the Public’s Attitudes Toward the Public Schools. PDK hires... 
relationships | campaign | poll | director | outreach | PDK
Journal Article
International Journal of Cancer, ISSN 0020-7136, 02/2016, Volume 138, Issue 4, pp. 809 - 817
Journal Article
Nutrition and Metabolism, ISSN 1743-7075, 02/2014, Volume 11, Issue 1, pp. 10 - 10
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2015, Volume 14, Issue 9, pp. 1389 - 1402
Rhadomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. RMS cells resemble fetal myoblasts but are unable to complete myogenic... 
differentiation therapy | metabolism and cancer | miR-206 | Rhabdomyosarcoma | Differentiation therapy | MiR-206 | Metabolism and cancer | HMT, Histone MethylTransferase | PPP, Pentose Phosphate Pathway | MYOBLAST DIFFERENTIATION | MREs, MicroRNA Responsive Elements | DHEA, Dehydroepiandrosterone | DCA, Dichloroacetate | MRFs, Myogenic Regulatory Factors | DICHLOROACETATE DCA | CYCLIN D1 | G6PD, Glucose 6 Phosphate Dehydrogenase | myomiRs, muscle-specific microRNAs | MIR-206 | PDK, Pyruvate Dehydrogenase Kinase | CELL BIOLOGY | GLUCOSE-6-PHOSPHATE-DEHYDROGENASE | TARGET GENES | RMS, Rhabdomyosarcoma | ALVEOLAR RHABDOMYOSARCOMA | SKELETAL | TCA cycle, TriCarboxylic Acid cycle | PDH, Pyruvate Dehydrogenase | EXPRESSION | SMYD1, SET and MYND domain-containing protein 1 | HISTONE METHYLTRANSFERASE | Cell Proliferation | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | DNA-Binding Proteins - metabolism | Rhabdomyosarcoma, Embryonal - genetics | Transfection | RNA Interference | Time Factors | Cell Transformation, Neoplastic - genetics | Muscle Proteins - metabolism | Rhabdomyosarcoma, Alveolar - pathology | Transcription, Genetic | Rhabdomyosarcoma, Embryonal - pathology | Rhabdomyosarcoma, Alveolar - drug therapy | Rhabdomyosarcoma, Alveolar - genetics | Rhabdomyosarcoma, Embryonal - enzymology | Signal Transduction | Rhabdomyosarcoma, Embryonal - drug therapy | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Myoblasts - pathology | Cell Transformation, Neoplastic - metabolism | Muscle Proteins - genetics | Transcription Factors - metabolism | Phenotype | Muscle Development - drug effects | Energy Metabolism | Rhabdomyosarcoma, Alveolar - enzymology | Cell Differentiation - drug effects | Dichloroacetic Acid - pharmacology | Muscle Fibers, Skeletal - pathology | Cell Line, Tumor | Glucosephosphate Dehydrogenase - metabolism | MicroRNAs - genetics | Glucosephosphate Dehydrogenase - genetics | Cell Transformation, Neoplastic - pathology | Myoblasts - enzymology | Muscle Fibers, Skeletal - enzymology
Journal Article
Molecular Metabolism, ISSN 2212-8778, 2013, Volume 3, Issue 1, pp. 29 - 41
Abstract Circadian rhythms control metabolism and energy homeostasis, but the role of the skeletal muscle clock has never been explored. We generated... 
Endocrinology & Metabolism | Circadian rhythms | Glucose metabolism | Glucose uptake | Muscle insulin resistance | Bmal1 | Skeletal muscle | ENDOCRINOLOGY & METABOLISM
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 05/2013, Volume 1833, Issue 5, pp. 1147 - 1156
The Warburg effect is known to be crucial for cancer cells to acquire energy. Nutrient deficiencies are an important phenomenon in solid tumors, but the effect... 
AMPK | Starvation | PDK | ROS | Warburg effect | Apoptosis | LACTIC-ACID | OXIDATIVE STRESS | CANCER CELLS | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL METABOLISM | TUMOR | HYPOXIA | CELL METABOLISM | CELL BIOLOGY | OXYGEN | GLUCOSE-METABOLISM | Phosphates | Glucose metabolism | Glucose | Dextrose
Journal Article
by Chang, JS and Ge, T
PROCEEDINGS OF THE IEEE, ISSN 0018-9219, 10/2019, Volume 107, Issue 10, pp. 2106 - 2117
Sensing and its electronics based on printed/flexible electronics offer unique attributes of mechanical flexibility of its substrate, hence the unique... 
Printing | Ring oscillators | Additives | printed electronics | Thin film transistors | organic electronics | Substrates | process development kit (PDK) | ENGINEERING, ELECTRICAL & ELECTRONIC | process variation | fully additive | FLEXIBLE ORGANIC TRANSISTORS | INTEGRATED-CIRCUITS | Bending | Robot sensing systems | THIN-FILM TRANSISTORS
Journal Article
PHI DELTA KAPPAN, ISSN 0031-7217, 11/2017, Volume 99, Issue 3, pp. 79 - 79
PDK is launching the American Voice Campaign to raise funds to support the work of the PDK Poll of the Public's Attitudes Toward the Public Schools. PDK hires... 
EDUCATION & EDUCATIONAL RESEARCH | relationships | PDK | director | outreach | campaign | poll
Journal Article
IEEE Journal of Selected Topics in Quantum Electronics, ISSN 1077-260X, 09/2019, Volume 25, Issue 5, pp. 1 - 14
A foundry-based photonic ecosystem is expected to become necessary with increasing demand and adoption of photonics for commercial products. To make... 
foundry | photonics ecosystem | design flow | fabless design | Photonics | Fabrication | Geometry | CMOS | Foundries | Silicon | Circuit synthesis | photonic integrated circuits(PICs) | process design kit (PDK) | Integrated circuit modeling | circuit design
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 1, pp. 29 - 42
mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A/protein kinase G/protein... 
Phosphoinositide 3-kinase (PI3K) | Akt/protein kinase B (PKB) | Serum and glucocorticoid protein kinase (SGK) | P70 ribosomal S6 kinase (S6K) | Kinase inhibitor | Cancer | IN-VIVO ROLE | PROTEIN-KINASE B/AKT | BINDING PARTNER | RAG GTPASES | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | AKT | IDENTIFICATION | P70 S6 KINASE | kinase inhibitor | phosphoinositide 3-kinase (PI3K) | p70 ribosomal S6 kinase (S6K) | HYDROPHOBIC MOTIF | cancer | serum and glucocorticoid protein kinase (SGK) | PDK1 | Cell Line | Humans | Multiprotein Complexes | Morpholines - pharmacology | Transcription Factors - antagonists & inhibitors | Gene Expression Profiling | G1 Phase - drug effects | Pyrimidines - pharmacology | Morpholines - chemistry | Pyrimidines - chemistry | Mechanistic Target of Rapamycin Complex 1 | Gene Expression Regulation - drug effects | Proteins | Transcription Factors - metabolism | Animals | Fibroblasts - drug effects | Cell Proliferation - drug effects | Mice | TOR Serine-Threonine Kinases | Fibroblasts - metabolism | PI3K, phosphoinositide 3-kinase | PDK, 3-phosphoinositide-dependent protein kinase | AMPK, AMP-activated protein kinase | mTORC, mTOR complex | DTT, dithiothreitol | SPHK, sphingosine kinase | ERK, extracellular-signal-regulated kinase | RSK, ribosomal S6 kinase | PH domain, pleckstrin homology domain | protein kinase B (PKB) | protein kinase G | NDRG1, N-Myc downstream-regulated gene-1 | IGF, insulin-like growth factor | mTOR, mammalian target of rapamycin | GST, glutathione transferase | SGK, serum and glucocorticoid protein kinase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | eIF4E, eukaryotic initiation factor 4E | 4E-BP1, eIF4E-binding protein 1 | protein kinase C family | Akt | PRAS40, proline-rich Akt substrate of 40 kDa | HEK-293 cell, human embryonic kidney 293 cell | MEF, mouse embryonic fibroblast | AGC family, protein kinase A | MAPK, mitogen-activated protein kinase
Journal Article
ISPRS International Journal of Geo-Information, ISSN 2220-9964, 03/2018, Volume 7, Issue 3, p. 111
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases.... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Organic Process Research & Development, ISSN 1083-6160, 02/2017, Volume 21, Issue 2, pp. 231 - 240
An efficient route to (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide 1, a new topical antiandrogen, is described. The target compound... 
ANDROGEN RECEPTOR | COMPLEX | DESIGN | PDK INHIBITOR | ACNE | DOUBLE-BLIND | CHEMISTRY, ORGANIC | FLUTAMIDE | HIRSUTISM | ALPHA-HYDROXYAMIDES | AZD7545 | CHEMISTRY, APPLIED
Journal Article