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2013, ISBN 9780691149615, cm.
The brain sciences are influencing our understanding of human behavior as never before, from neuropsychiatry and neuroeconomics to neurotheology and... 
Neuropsychology | JHB | PDX | Psychology | Science | JMM | History | Social Science | Life Sciences | Neuroscience | Sociology | PSAN | General | History of Science & Technology | Biological Sciences | SOCIAL SCIENCE | SCIENCE
eBook
2012, ISBN 0691155313, xvi, 211
Warriors of the Cloisters tells how key cultural innovations from Central Asia revolutionized medieval Europe and gave rise to the culture of science in the... 
Science | Academic disputations | History | Science, Medieval | Medieval | Education | Asia | PDX | HBLC1 | Europe | General | 1FC | History of Science & Technology | To 1500 | Asia, Central | HISTORY
Book
Nuclear Fusion, ISSN 0029-5515, 08/2017, Volume 57, Issue 11, p. 116033
This paper describes the recent progress in divertor simulation research using the GAMMA 10/PDX tandem mirror towards the development of divertors in fusion... 
divertor simulation | GAMMA 10/PDX | tandem mirror | plasma detachment | D-MODULE | PLASMA | PHYSICS, FLUIDS & PLASMAS | GAMMA10/PDX | MODEL | RESEARCH PLAN | NUMERICAL-SIMULATION | END-CELL
Journal Article
2013, ISBN 9780691157733, Volume 9781400848805, xxxvii, 634 pages, 29 colour plates
In this sweeping and richly illustrated history, S. Frederick Starr tells the fascinating but largely unknown story of Central Asia's medieval enlightenment... 
Asia, Central History | History | History of Science & Technology | Religion | Asia, Central | To 1500 | Philosophy | Asia, Central-History-To 1500
Book
Cancer cell, ISSN 1535-6108, 2016, Volume 30, Issue 6, pp. 849 - 862
Tumor relapse is associated with dismal prognosis, but responsible biological principles remain incompletely understood. To isolate and characterize... 
RNA single-cell sequencing | minimal residual disease (MRD) | acute lymphoblastic leukemia | patient-derived xenograft (PDX) cells | Cancer stem cells | primary patients' ALL MRD cells | dormant tumor cells | treatment resistance | INITIATING CELLS | STEM-CELLS | ONCOLOGY | MYELOID-LEUKEMIA | PROPAGATING CELLS | MINIMAL RESIDUAL DISEASE | CANCER | CHILDHOOD | CHEMOTHERAPY | DISCOVERY | XENOGRAFTS | CELL BIOLOGY | Neoplasm, Residual - pathology | Neoplasm Transplantation | Cell Proliferation | Prognosis | Humans | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Neoplasm Recurrence, Local - pathology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Neoplastic Stem Cells - pathology | Adult | Tumor Cells, Cultured | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Single-Cell Analysis | Child | Antineoplastic Combined Chemotherapy Protocols - metabolism | Gene Expression Profiling - methods | Neoplasm, Residual - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Sequence Analysis, RNA - methods | Disease-Free Survival | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoplasm Recurrence, Local - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Medical colleges | Genetic vectors | Genetically modified organisms | Genetic engineering | Research institutes | Acute lymphocytic leukemia | Health aspects | Index Medicus
Journal Article
Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 59, pp. 31397 - 31410
Epigenetic regulation is crucial in mammalian development and maintenance of tissue-cell specific functions. Perturbation of epigenetic balance may lead to... 
Epigenetic drug | Synergism effect | Ewing sarcoma | EWSR1 | PDX
Journal Article
Cancer discovery, ISSN 2159-8290, 2014, Volume 4, Issue 9, pp. 998 - 1013
Journal Article
Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 51, pp. 29587 - 29600
Breast cancer is a complex disease in which each patient could present several genetic alterations that are therapeutically relevant in cancers. Here we... 
Breast cancer | BRCA2 | PDX | DNA repair | MTOR
Journal Article
Frontiers in oncology, ISSN 2234-943X, 01/2020, Volume 9
In recent years, molecular profiling has led to the discovery of an increasing number of brain tumor subtypes, and associated therapeutic targets. These... 
Pediatrics | Brain tumors | xenograft | PDX | orthotopic | WHO classification | pediatric
Journal Article
Frontiers in microbiology, ISSN 1664-302X, 2018, Volume 9, p. 789
Endogenous retroviruses are remnants of retroviral infections. In contrast to their human counterparts, murine endogenous retroviruses (mERV) still can... 
MERV | PDX-derived cell lines | Expression | PDX | CDX | Colorectal cancer | expression | colorectal cancer | LEUKEMIA-VIRUS | IN-VIVO | MICROBIOLOGY | ESTABLISHMENT | mERV | Physiological aspects | Retroviruses | Health aspects | Cancer cells
Journal Article
Molecular cell, ISSN 1097-2765, 2018, Volume 72, Issue 1, pp. 71 - 83.e7
Cancer cells entail metabolic adaptation and microenvironmental remodeling to survive and progress. Both calcium (Ca2+) flux and Ca2+-dependent signaling play... 
NF-κB | Ca2 | PDX | signal transduction | glycolysis | LncRNA | cancer | metabolism | tumor microenvironment | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIPPO | RESISTANCE | KAPPA-B PATHWAY | INCRNA | CANCER | CELL BIOLOGY
Journal Article
Molecular cancer therapeutics, ISSN 1535-7163, 06/2019, Volume 18, Issue 6, pp. 1115 - 1126
One of the most recent advances in the treatment of HER2+ breast cancer is the development of the antibody-drug conjugate, T-DM1. T-DM1 has proven clinical... 
ADC | BCL-2 | BCL-XL | PDX | Breast | apoptosis | T-DM1 | ABT-263 | HER2 | Cytotoxic
Journal Article
2013, REV - Revised, ISBN 0691147531, 450 p., [8] p. of plates
Dreams of Other Worlds describes the unmanned space missions that have opened new windows on distant worlds. Spanning four decades of dramatic advances in... 
Space probes | Outer space Exploration | Space flights | Science: General Issues | Science | Astronomy- Science | Space Science- Science | Astrophysics- Pdz- Pg- Pdx- Phvb- Ttd | History- Science | Physics | History of Science & Technology | General Science | Astronomy | Exploration | History | Outer space | Space robotics
Book
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 27, pp. 19294 - 19306
Heparanase, the sole heparan sulfate (HS) degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis,... 
Journal Article
Zhonghua wei chang wai ke za zhi, ISSN 1671-0274, 2017, Volume 20, Issue 5, pp. 596 - 600
新型药物的研发是肿瘤转化医学研究的重要组成部分,临床前动物模型的建立与应用是新型药物研发和鉴定的关键与核心.人源肿瘤组织来源移植瘤模型(PDX模型)由于能够相对准确地反映原始肿瘤异质性及遗传信息多样性,从而可更准确地预测新型药物的临床疗效.PDX模型多通过外科手术、... 
Journal Article
Frontiers in Plant Science, ISSN 1664-462X, 05/2013, Volume 4, Issue MAY
Vitamin B6 has an essential role in cells as a cofactor for several metabolic enzymes. It has also been shown to function as a potent antioxidant molecule. The... 
Biofortification | Oxidative stress | Genetic engineering | Crop biotechnology | Vitamin B6 | PDX genes | Genetic Engineering | Oxidative Stress | biofortification
Journal Article
2013, Revised edition, ISBN 9780691139685, x, 332
"Einstein and the Quantum reveals for the first time the full significance of Albert Einstein's contributions to quantum theory. Einstein famously rejected... 
Science | Physicists | Einstein, Albert, 1879-1955 | History | Quantum theory | Physics | Quantum Theory | PDX | PDZ | PHQ | General | SCIENCE | BIOGRAPHY & AUTOBIOGRAPHY | BGT | Science & Technology | History of Science & Technology | Biography | Einstein, Albert, 1879–1955 | 1879-1955 | Einstein, Albert | Einstein, Albert,-1879-1955 | Physicists-Biography | Science-History
Book