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Chemical Society Reviews, ISSN 0306-0012, 05/2011, Volume 40, Issue 5, pp. 2131 - 2145
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2, p. e0117668
PDZ domains in general, and those of PSD-95 in particular, are emerging as promising drug targets for diseases such as ischemic stroke. We have previously... 
GLUTAMATE RECEPTORS | FLUORESCENCE POLARIZATION | RECEPTOR INTERACTION | DIMERIC INHIBITOR | PDZ DOMAIN | MULTIDISCIPLINARY SCIENCES | GUANYLATE KINASE PROTEINS | SUPERTERTIARY STRUCTURE | BINDING SELECTIVITY | ISCHEMIC BRAIN-DAMAGE | POSTSYNAPTIC DENSITY | Disks Large Homolog 4 Protein | Guanylate Kinases - genetics | Tumor Suppressor Proteins - antagonists & inhibitors | Guanylate Kinases - antagonists & inhibitors | Protein Multimerization | Intracellular Signaling Peptides and Proteins - metabolism | Peptides - metabolism | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Tumor Suppressor Proteins - genetics | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Binding, Competitive | Amino Acid Sequence | Tumor Suppressor Proteins - metabolism | Peptides - chemistry | Membrane Proteins - genetics | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Binding Sites - genetics | Transcription Factors - genetics | Peptides - pharmacology | Transcription Factors - metabolism | Membrane Proteins - antagonists & inhibitors | Mutagenesis | Nuclear Proteins - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - genetics | Guanylate Kinases - metabolism | PDZ Domains | Protein Binding | Ligands | Kinetics | Adaptor Proteins, Signal Transducing - metabolism | Fluorescence Polarization | Stroke (Disease) | Proteins | Cysteine | Chemical properties | Ischemia | Protein-protein interactions | Binding | Fluorescence polarization | Stroke | Disease | Peptides | Fluorescence | Biochemistry | Pharmacology | Kinases | Studies | Spectrometry | Inhibitors | Guanylate kinase | Rodents | Brain damage | Affinity | Postsynaptic density proteins | Protein interaction | Basic Medicine | Medical Biotechnology | Medical and Health Sciences | Microbiology in the medical area | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Medicinsk bioteknologi | Mikrobiologi inom det medicinska området | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci)
Journal Article
The FEBS Journal, ISSN 1742-464X, 01/2018, Volume 285, Issue 1, pp. 46 - 71
Assembly and disassembly of protein–protein complexes needs to be dynamically controlled and phosphoswitches based on linear motifs are crucial in this... 
mitogen‐activated kinases | PDZ domain | protein phosphorylation | extracellular signal–regulated kinase | linear‐binding motif | signal transduction | mitogen-activated kinases | linear-binding motif | LOCALIZATION | extracellular signal-regulated kinase | DOMAIN | ACTIVATION | PROTEIN | SPECIFICITY | PHOSPHORYLATION | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | MAGI-1 PDZ1 | BINDING | Phosphorylation | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Humans | Serine - genetics | Substrate Specificity | Crystallography, X-Ray | Binding Sites - genetics | Ribosomal Protein S6 Kinases, 90-kDa - chemistry | Serine - chemistry | Serine - metabolism | Molecular Dynamics Simulation | Mitogen-Activated Protein Kinase 1 - chemistry | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | Ribosomal Protein S6 Kinases, 90-kDa - genetics | HEK293 Cells | Protein Binding | Protein Conformation | Enzyme Activation | Mitogen-Activated Protein Kinase 3 - chemistry | Mitogen-Activated Protein Kinase 1 - metabolism | Cellular signal transduction | Epidermal growth factor | Mitogens | Protein kinases | Protein-protein interactions | Protein binding | Binding | Residues | Nuclear magnetic resonance--NMR | Switches | Extracellular signal-regulated kinase | Kinases | Masks | Substrates | Data bases | MAGI-1 protein | Proteins | Dynamic control | Cores | Ribosomal protein S6 kinase | Signaling | Allosteric properties | Databases | Signal processing | Protein interaction | Dismantling
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2012, Volume 109, Issue 14, pp. E812 - E820
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2009, Volume 158, Issue 2, pp. 494 - 506
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2000, Volume 2, Issue 8, pp. 531 - 539
PAR (partitioning-defective) proteins, wh ich were first identified in the nematode Caenorhabditis elegans, are essential for asymmetric cell division and... 
GTPASE-BINDING DOMAIN | PDZ-DOMAIN | COMPLEX | CAENORHABDITIS-ELEGANS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DROSOPHILA NEUROBLASTS | RHO-GTPASES | POLARIZATION | BAZOOKA | COLOCALIZES | FAMILY | CELL BIOLOGY | Adaptor Proteins, Signal Transducing - chemistry | Cell Polarity | Epithelial Cells - metabolism | Humans | Protein-Serine-Threonine Kinases | Helminth Proteins - chemistry | Molecular Sequence Data | RNA, Messenger - analysis | Substrate Specificity | cdc42 GTP-Binding Protein - metabolism | Guanosine Triphosphate - metabolism | Isoenzymes - chemistry | Phosphoproteins - metabolism | Tight Junctions - chemistry | Isoenzymes - metabolism | Protein Kinase C - metabolism | Membrane Proteins - metabolism | Epithelial Cells - cytology | Helminth Proteins - metabolism | Protein Structure, Tertiary | Tight Junctions - metabolism | Amino Acid Sequence | Cell Line | Caenorhabditis elegans Proteins | RNA, Messenger - genetics | Helminth Proteins - genetics | Macromolecular Substances | Proteins - genetics | Two-Hybrid System Techniques | Sequence Alignment | Animals | Proteins - metabolism | Zonula Occludens-1 Protein | Protein Kinase C - chemistry | rho GTP-Binding Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Dogs | Fluorescent Antibody Technique | Protein Binding | Mice | Proteins - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Physiological aspects | Cell division | Polarity (Biology) | Research | Protein kinases
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 39, pp. 14141 - 14146
Journal Article
Science, ISSN 0036-8075, 2/2003, Volume 299, Issue 5609, pp. 1061 - 1064
How scaffold proteins control information flow in signaling pathways is poorly understood: Do they simply tether components, or do they precisely orient and... 
Yeasts | Engineering | Phosphorylation | Drug interactions | Reproductive efficiency | Reports | Topology | Scaffolds | Binding sites | YEAST | ORGANIZATION | ACTIVATION | MULTIDISCIPLINARY SCIENCES | PDZ-DOMAIN PROTEIN | STE5 | PROTEIN-PROTEIN INTERACTIONS | CASCADE | SACCHAROMYCES-CEREVISIAE | MUTATIONAL ANALYSIS | SIGNALING COMPLEX | Protein Kinases - metabolism | Protein Kinases - genetics | Substrate Specificity | Recombinant Fusion Proteins - metabolism | MAP Kinase Signaling System | Saccharomyces cerevisiae - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Osmolar Concentration | Carrier Proteins - chemistry | Membrane Proteins - metabolism | Binding Sites | Protein Structure, Tertiary | Saccharomyces cerevisiae - physiology | MAP Kinase Kinase Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | Saccharomyces cerevisiae Proteins - genetics | Protein Precursors - metabolism | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Carrier Proteins - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Saccharomyces cerevisiae - enzymology | Protein Conformation | Mutation | Evolution, Molecular | Mitogen-Activated Protein Kinases - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Proteins | Biochemistry | Genetic aspects | Research | Protein kinases | Pharmacology
Journal Article