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pelp1 (54) 54
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Molecules, ISSN 1420-3049, 07/2019, Volume 24, Issue 15, p. 2783
The interaction between androgen receptor (AR) and coactivator proteins plays a critical role in AR-mediated prostate cancer (PCa) cell growth, thus its... 
Index Medicus | α-helix mimetics | bis-benzamide scaffold | protein–protein interaction | coactivator PELP1 | prostate cancer | androgen receptor
Journal Article
JOURNAL OF THORACIC ONCOLOGY, ISSN 1556-0864, 01/2017, Volume 12, Issue 1, pp. S1139 - S1139
Conference Proceeding
Breast Cancer Research and Treatment, ISSN 0167-6806, 11/2011, Volume 130, Issue 2, pp. 377 - 385
The estrogen receptor (ER) is implicated in the progression of breast cancer. Despite positive effects of hormonal therapy, initial or acquired resistance to... 
Estrogen receptor | Therapy resistance | Medicine & Public Health | Src | Oncology | Breast cancer | HER2 | Extranuclear signaling | PELP1 | COREGULATOR | TAMOXIFEN | MECHANISMS | ESTROGEN-RECEPTOR | BREAST-CANCER CELLS | PROLINE-RICH | ONCOLOGY | RECEPTOR COACTIVATOR PELP1/MNAR | NONGENOMIC ACTIONS | AROMATASE INHIBITORS | GLUTAMIC-ACID-RICH | Phosphorylation | Nitriles - pharmacology | Humans | Receptor, ErbB-2 - metabolism | Co-Repressor Proteins - metabolism | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Thiazoles - therapeutic use | Gene Knockdown Techniques | RNA Interference | src-Family Kinases - metabolism | Estrogen Receptor alpha - metabolism | Female | Antineoplastic Agents - pharmacology | Triazoles - therapeutic use | Dasatinib | Pyrimidines - pharmacology | Transcription Factors - genetics | Breast Neoplasms - drug therapy | Co-Repressor Proteins - genetics | Drug Synergism | Transcription Factors - metabolism | Triazoles - pharmacology | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Breast Neoplasms - pathology | Mice, Nude | Pyrimidines - therapeutic use | Tamoxifen - therapeutic use | Tamoxifen - pharmacology | Cell Line, Tumor | Mice | Thiazoles - pharmacology | src-Family Kinases - genetics | Mitogen-Activated Protein Kinases - metabolism | Nitriles - therapeutic use | Analysis | Estrogen | Development and progression | Postmenopausal women | Tamoxifen | Health aspects | Tumors | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 01/2015, Volume 34, Issue 4, pp. 506 - 515
Journal Article
Oncogene, ISSN 0950-9232, 07/2014, Volume 33, Issue 28, pp. 3707 - 3716
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 2014, Volume 21, Issue 9, pp. 1409 - 1418
Journal Article
Cancer research, ISSN 0008-5472, 5/2010, Volume 70, Issue 10, pp. 4092 - 4101
The molecular basis of breast cancer progression to metastasis and the role of estrogen receptor (ER) signaling in this process remain poorly understood.... 
breast cancer | extranuclear signaling | estrogen receptor | coactivator | PELP1
Journal Article
CANCER RESEARCH AND TREATMENT, ISSN 1598-2998, 04/2019, Volume 51, Issue 2, pp. 706 - 717
Purpose Proline, glutamic acid, and leucine-rich protein 1 (PELP1), a novel nuclear receptor (NR) co-regulator, is highly expressed in breast cancer. We... 
Immunohistochemistry | ANDROGEN RECEPTOR | COACTIVATOR | Prognosis | ESTROGEN-RECEPTOR | PROLINE-RICH | ONCOLOGY | PROTEIN-1/MODULATOR | Breast neoplasms | Differential diagnosis | PROGNOSTIC-SIGNIFICANCE | NONGENOMIC ACTIVITY | POTENTIAL ROLE | EXPRESSION | PELP1 | GLUTAMIC-ACID-RICH | Original
Journal Article
International Journal of Obesity and Related Metabolic Disorders, ISSN 0307-0565, 2015, Volume 39, Issue 2, pp. 331 - 338
BACKGROUND/OBJECTIVES: In the context of obesity, epigenetic mechanisms regulate cell-specific chromatin plasticity, perpetuating gene expression responses to... 
LIVER-DISEASE NAFLD | THERMOGENESIS | OBESITY | NUTRITION & DIETETICS | CHROMATIN | HISTONE VARIANT MACROH2A | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | NONALCOHOLIC STEATOHEPATITIS | TRANSCRIPTIONAL COREGULATOR PELP1 | EXPRESSION | BINDING | Obesity | Care and treatment | Physiological aspects | Histones | Genetic aspects | Research | Gene expression | Risk factors | Index Medicus
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 07/2018, Volume 103, pp. 336 - 345
Endometrial carcinoma (EC) is the most common malignant gynecologic tumor in women. EC is thought to be caused by increasing estrogen levels relative to... 
Antiproliferative | Endometrium cancer | Genomics | Microarray | Bioinformatics | Hesperidin | Apoptosis | TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | MTOR | PATHOGENESIS | OBESITY | GENE | OCCURS | PHARMACOLOGY & PHARMACY | PI3K/AKT/MTOR PATHWAY | PELP1 | Membrane lipids | Endometrial cancer | Estrogen | Phenols | Genetic research | Biochemistry | Progesterone | Molecular biology | Cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 48, pp. E6673 - E6682
Journal Article
MOLECULAR ONCOLOGY, ISSN 1574-7891, 03/2014, Volume 8, Issue 2, pp. 389 - 400
Proline-, glutamic acid-, and leucine-rich protein 1 (PELP1) is a proto-oncogene that functions as coactivator of the estrogen receptor and is an independent... 
PRMT6 | Alternative splicing | COACTIVATOR | PROTEIN | RNA HELICASE | RECEPTOR | Breast cancer | BREAST-CANCER | PROLINE-RICH | GENE | ONCOLOGY | Epigenetics | EXPRESSION | PELP1 | ENDOTHELIAL GROWTH-FACTOR | GLUTAMIC-ACID-RICH
Journal Article