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Chemistry – An Asian Journal, ISSN 1861-4728, 04/2015, Volume 10, Issue 4, pp. 865 - 868
An efficient synthetic route toward the highly congested [5‐6‐7] tricyclic core of calyciphylline A‐type alkaloids has been developed. This approach features a... 
natural products | daphniphyllum alkaloids | Diels–Alder | calyciphylline A‐type | ring expansion | calyciphylline A-type | Diels-Alder | DIELS-ALDER REACTIONS | ABC RING-SYSTEM | RAPID CONSTRUCTION | DAPHNICYCLIDIN | TETRACYCLIC CORE | PENTACYCLIC ALKALOIDS | CHEMISTRY, MULTIDISCIPLINARY | SKELETON | DAPHNILACTONE-B | STEREOCONTROLLED SYNTHESIS | Alkaloids | Cyclopropane compounds
Journal Article
Synthetic Communications, ISSN 0039-7911, 08/2015, Volume 45, Issue 16, pp. 1912 - 1919
A stereoselective approach to spiro-annulated bicyclo[2.2.2]octane ring system related to the tetracyclic skeleton of daphmanidin A-type alkaloids is... 
bicyclo[2.2.2]octane | Alkylation | ring-closing metathesis | ORGANIC-SYNTHESIS | OXIDATIVE DEAROMATIZATION | (-)-CALYCIPHYLLINE N | NATURAL-PRODUCTS | STEREOSELECTIVE ROUTE | CHEMISTRY, ORGANIC | WACKER OXIDATION | DAPHNIPHYLLUM ALKALOIDS | PENTACYCLIC ALKALOIDS | ALDER REACTION
Journal Article
Nature Chemistry, ISSN 1755-4330, 08/2013, Volume 5, Issue 8, pp. 679 - 684
The Daphniphyllum alkaloids are a large class of natural products isolated from a genus of evergreen plants widely used in Chinese herbal medicine. They... 
BIOMIMETIC TOTAL-SYNTHESIS | (+/-)-METHYL HOMODAPHNIPHYLLATE | RAPID CONSTRUCTION | SILYL ENOL ETHERS | TETRACYCLIC CORE | PENTACYCLIC ALKALOIDS | RING-SYSTEM | CARBON TRICYCLIC CORE | ELECTROCYCLIZATIONS | CHEMISTRY, MULTIDISCIPLINARY | SKELETON | Alkaloids - chemical synthesis | Saxifragaceae - chemistry | Catalysis
Journal Article
by Xiong, XC and Li, Y and Lu, ZY and Wan, M and Deng, J and Wu, SH and Shao, HW and Li, A
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 2014, Volume 50, Issue 40, pp. 5294 - 5297
An efficient approach toward the synthesis of the 6,6,5,7-tetracyclic core of the daphnilongeranin B, a Daphniphyllum alkaloid, is reported. The bridged... 
BIOMIMETIC TOTAL-SYNTHESIS | (+/-)-METHYL HOMODAPHNIPHYLLATE | CONSTRUCTION | TETRACYCLIC CORE | DAPHENYLLINE | DAPHNIPHYLLUM ALKALOIDS | PENTACYCLIC ALKALOIDS | RING-SYSTEM | CARBON TRICYCLIC CORE | DAPHNIGLAUCIN-C | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Chemical Reviews, ISSN 0009-2665, 03/2017, Volume 117, Issue 5, pp. 4104 - 4146
Daphniphyllum is an evergreen species known since 1826. After initial systematic investigations, more than 320 members of this family have been isolated, which... 
BIOMIMETIC TOTAL-SYNTHESIS | DAPHNILACTONE-B | ABC RING-SYSTEM | TETRACYCLIC CORE | PENTACYCLIC ALKALOIDS | FUSED-HEXACYCLIC SKELETON | ASYMMETRIC TOTAL-SYNTHESIS | CARBON TRICYCLIC CORE | CHEMISTRY, MULTIDISCIPLINARY | STEREOCONTROLLED SYNTHESIS | CALYCIPHYLLINE-A | Saxifragaceae - chemistry | Alkaloids - chemistry
Journal Article
Natural Product Reports, ISSN 0265-0568, 3/2014, Volume 31, Issue 4, pp. 55 - 562
Covering: up to September 2013 The Daphniphyllum alkaloids are a diverse family of natural products rich in number and structural diversity that have been... 
CHEMISTRY, MEDICINAL | RAPID CONSTRUCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | TETRACYCLIC CORE | PENTACYCLIC ALKALOIDS | CARBON TRICYCLIC CORE | CYCLIC ENOL ETHERS | POLYCYCLIC ETHERS | DAPHNILACTONE-B | BRIARELLIN DITERPENES | RING-CLOSING METATHESIS | ENANTIOSELECTIVE TOTAL-SYNTHESIS
Journal Article
Nat. Prod. Rep, ISSN 0265-0568, 2014, Volume 31, Issue 4, pp. 550 - 562
Covering: up to September 2013The Daphniphyllum alkaloids are a diverse family of natural products rich in number and structural diversity that have been known... 
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2003, Volume 44, Issue 37, pp. 7091 - 7094
The pentacyclic core of ecteinascidins was constructed from two fundamental building blocks, the 1,2,3,4-tetrahydroisoquinoline derivative and the substituted... 
Pictet–Spengler cyclization | pentacyclic core | L-Dopa | ecteinascidins | Ecteinascidins | Pentacyclic core | Pictet-Spengler cyclization | CYCLIZATIONS | PHTHALASCIDIN | CHEMISTRY, ORGANIC
Journal Article
Organic Letters, ISSN 1523-7060, 07/2006, Volume 8, Issue 15, pp. 3299 - 3301
The asymmetric synthesis of a highly functionalized tetrahydroisoquinoline relevant to the total synthesis of Et-743 is described. The key step involves a... 
PENTACYCLIC INTERMEDIATE | CHEMISTRY | CHEMISTRY, ORGANIC | ECTEINASCIDIN | (-)-TETRAZOMINE | STRATEGY | Molecular Structure | Tetrahydroisoquinolines - chemical synthesis | Cyclization | Dioxoles - chemical synthesis | Stereoisomerism | Imines - chemistry
Journal Article
Chemical Communications, ISSN 1359-7345, 2017, Volume 54, Issue 2, pp. 196 - 199
Journal Article
Journal Article
Synthesis, ISSN 0039-7881, 09/2012, Volume 44, Issue 17, pp. 2743 - 2753
Abstract An alternative synthetic route to an intermediate in the synthesis of ecteinascidin 743 has been established by using a Pictet–Spengler reaction and a... 
paper | total synthesis | anticancer drugs | Pictet-Spengler reaction | Friedel-Crafts reaction | alkaloids | PRACTICAL SYNTHESIS | CHEMISTRY, ORGANIC | ALPHA-ARYLGLYCINE DERIVATIVES | FORMAL TOTAL-SYNTHESIS | PENTACYCLIC CORE | ANTICANCER DRUG | CARIBBEAN TUNICATE | PICTET-SPENGLER CYCLIZATION | ABC RING MODEL | CHIRAL TEMPLATE | MINOR-GROOVE
Journal Article
by Li, HJ and Wang, JL and Wang, R and Luo, DH and Wu, YC
JOURNAL OF CHEMISTRY, ISSN 2090-9063, 2013, Volume 2013, pp. 1 - 9
4H-Chromene-2-carboxylic acid ester derivatives of renieramycin M might be of use for the structural-activity relationship studies of antitumor antibiotic... 
RENIERAMYCIN-M | TETRAHYDROISOQUINOLINE ANTITUMOR ANTIBIOTICS | (-)-QUINOCARCIN | NAPHTHYRIDINOMYCIN | CHEMISTRY | FORMAL TOTAL-SYNTHESIS | PENTACYCLIC CORE | ASYMMETRIC TOTAL-SYNTHESIS | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY | L-TYROSINE
Journal Article