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Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 850 - 858
The success of antitumor immune responses depends on the infiltration of solid tumors by effector T cells, a process guided by chemokines. Here we show that in... 
CD26 EXPRESSION | CELLS | CXCL10 | CHEMOKINE ACTIVITY | IN-VIVO | RECEPTOR | IMMUNOLOGY | CD26/DIPEPTIDYL PEPTIDASE-IV | PROTEINS | CANCER | POSTTRANSLATIONAL MODIFICATION | Dipeptidyl Peptidase 4 - metabolism | Immunotherapy - methods | Male | Adoptive Transfer | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Cell Movement - immunology | Flow Cytometry | Lymphocytes - immunology | Neoplasms, Experimental - immunology | Chemokine CXCL10 - immunology | Neoplasms, Experimental - genetics | Female | Sitagliptin Phosphate | Dipeptidyl Peptidase 4 - immunology | Chemokines - immunology | Lymphocytes - metabolism | Receptors, CXCR3 - metabolism | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Dipeptidyl Peptidase 4 - genetics | Mice, Transgenic | Mice, Knockout | Triazoles - pharmacology | Cell Movement - drug effects | Animals | Receptors, CXCR3 - immunology | Cell Line, Tumor | Chemokines - metabolism | Mice, Inbred BALB C | Pyrazines - pharmacology | Chemokine CXCL10 - metabolism | Care and treatment | Usage | Immunotherapy | Development and progression | Inflammation | Health aspects | Chemokines | Tumors | Neoplasms, Experimental/genetics | Immunotherapy/methods | Cell Movement/drug effects | Neoplasms, Experimental/therapy | Lymphocytes/metabolism | Lymphocytes/immunology | Dipeptidyl Peptidase 4/genetics | Life Sciences | Chemokine CXCL10/immunology | Immunology | Pyrazines/pharmacology | Dipeptidyl Peptidase 4/immunology | Dipeptidyl-Peptidase IV Inhibitors/pharmacology | Chemokines/metabolism | Receptors, CXCR3/immunology | Receptors, CXCR3/metabolism | Neoplasms, Experimental/immunology | Triazoles/pharmacology | Cell Movement/immunology | Chemokines/immunology | Dipeptidyl Peptidase 4/metabolism | Chemokine CXCL10/metabolism
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2011, Volume 19, Issue 16, pp. 4953 - 4970
Synthesis, inhibition of dipeptidyl peptidase IV (DPP-4) inhibitory activity of new isoquinolone ( ) are described. The design, synthesis, and... 
Anti-diabetic effects | Isoquinolone | Dipeptidyl peptidase IV (DPP-4) | CHEMISTRY, MEDICINAL | VIVO | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | RATS | CHEMISTRY, ORGANIC | IMPROVED GLUCOSE-TOLERANCE | IN-VITRO | HORMONE | GLUCAGON-LIKE PEPTIDE-1 | DEGRADATION | MICE | THIAZOLIDIDE | Dipeptidyl Peptidase 4 - drug effects | Rats, Wistar | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Quinolones - pharmacology | Structure-Activity Relationship | Molecular Targeted Therapy | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - antagonists & inhibitors | Isoquinolines - pharmacology | Peptides - metabolism | Quinolones - chemistry | Hypoglycemic Agents - administration & dosage | Quinolones - chemical synthesis | Quinolones - therapeutic use | Drug Design | Female | Dipeptidyl Peptidase 4 - analysis | Caco-2 Cells | Hypoglycemic Agents - therapeutic use | Glucose Tolerance Test | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - drug effects | Administration, Oral | Rats | Blood Glucose | Dipeptidyl-Peptidase IV Inhibitors - chemistry | Hypoglycemic Agents - chemistry | Dipeptidyl-Peptidase IV Inhibitors - administration & dosage | Hypoglycemic Agents - pharmacology | Dipeptidyl-Peptidase IV Inhibitors - chemical synthesis | Quinolones - administration & dosage | Animals | Isoquinolines - chemical synthesis | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - analysis | Hypoglycemic Agents - chemical synthesis | Isoquinolines - therapeutic use | Diabetes Mellitus, Type 2 - drug therapy | Isoquinolines - administration & dosage
Journal Article
FEBS Letters, ISSN 0014-5793, 11/2011, Volume 585, Issue 21, pp. 3409 - 3414
Journal Article
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 08/2018, Volume 119, Issue 8, pp. 6743 - 6755
Journal Article
Endocrinology, ISSN 0013-7227, 08/2011, Volume 152, Issue 8, pp. 3018 - 3029
Journal Article
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2006, Volume 396, Issue 2, pp. 391 - 399
Dipeptidyl peptidases 8 and 9 have been identified as gene members of the S9b family of dipeptidyl peptidases. In the present paper, we report the... 
Neuropeptide Y | Peptide YY | Valine pyrrolidide | Glucagon-like peptide | S9b family | Dipeptidyl peptidase | LOCALIZATION | COMPLEX | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | neuropeptide Y | HOMOLOG | FAMILY | MEMBER | SUBSTRATE-SPECIFICITY | POTENT | dipeptidyl peptidase | CLONING | glucagon-like peptide | valine pyrrolidide | IV/CD26 | peptide YY | Dipeptidyl Peptidase 4 - metabolism | Dipeptidases - metabolism | Baculoviridae - metabolism | Dipeptidyl Peptidase 4 - chemistry | Humans | Molecular Sequence Data | Substrate Specificity | Baculoviridae - genetics | Recombinant Proteins - isolation & purification | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism | Dipeptidases - isolation & purification | Protein Structure, Quaternary | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - genetics | Recombinant Proteins - metabolism | Amino Acid Sequence | Pyrroles - metabolism | Peptide Fragments - metabolism | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - isolation & purification | Enzyme Inhibitors - metabolism | Dipeptidases - genetics | Enzyme Inhibitors - pharmacology | Recombinant Proteins - genetics | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - chemistry | Dipeptidases - chemistry | Peptide Fragments - chemistry | Pyrroles - pharmacology | Sequence Alignment | Valine - metabolism | Enzyme Activation | Kinetics | Valine - pharmacology | Chromatography, Gel | ORF, open reading frame | DPP, dipeptidyl peptidase | NPY, neuropeptide Y | DLS, dynamic light scattering | EST, expressed sequence tag | ValPyr, valine pyrrolidide | pNA, p-nitroanilide | MALDI–TOF, matrix-assisted laser-desorption ionization–time-of-flight | GLP, glucagon-like peptide | PYY, peptide YY
Journal Article
1994, Methods in enzymology, ISBN 0121821455, Volume 244., xxi, 765
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