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Chemical science, ISSN 2041-6520, 05/2017, Volume 8, Issue 5, pp. 4051 - 4055
An antibacterial cyclic AS-48 protein was chemically synthesized by α-ketoacid-hydroxylamine (KAHA) ligation. Initial challenges associated with the... 
Journal Article
Chemical Science, ISSN 2041-6520, 2017, Volume 8, Issue 5, pp. 4051 - 4055
An antibacterial cyclic AS-48 protein was chemically synthesized by alpha-ketoacid-hydroxylamine (KAHA) ligation. Initial challenges associated with the... 
TRACELESS STAUDINGER LIGATION | AMINO-ACID | 5-OXAPROLINE | PEPTIDE ANTIBIOTIC AS-48 | CIRCULAR ENTEROCIN AS-48 | MEMBRANE-PROTEINS | CHEMISTRY, MULTIDISCIPLINARY | BACTERIOCIN AS-48 | MACROCYCLIZATION | CYCLIZATION | BUTELASE 1 | Proteins | Synthesis (chemistry) | Vesicles | Synthesis | Displays | Segments | Antiinfectives and antibacterials | Biological activity
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2017, Volume 61, Issue 4
We report the feasibility of enterocin AS-48, a circular cationic peptide produced by Enterococcus faecalis, as a new leishmanicidal agent. AS-48 is lethal to... 
Enterocin AS-48 | Bioenergetics | Intracellular parasite | Antimicrobial peptide | ACID | MEMBRANE | enterocin AS-48 | DRUG DISCOVERY | MITOCHONDRIA | ANTIBACTERIAL | MICROBIOLOGY | ANTIMICROBIAL PEPTIDES | PROGRAMMED CELL-DEATH | INHIBITION | DISEASES | bioenergetics | PEPTIDE ANTIBIOTIC AS-48 | PHARMACOLOGY & PHARMACY | antimicrobial peptide | intracellular parasite | Staining and Labeling - methods | Species Specificity | Fluorescent Dyes - metabolism | Adenosine Triphosphate - biosynthesis | Mitochondria - ultrastructure | Leishmania donovani - metabolism | Macrophages - parasitology | Adenosine Triphosphate - antagonists & inhibitors | Inhibitory Concentration 50 | Cell Membrane - metabolism | Cell Membrane - drug effects | Life Cycle Stages - drug effects | Life Cycle Stages - physiology | Cell Survival - drug effects | Leishmania donovani - drug effects | Enterococcus faecalis - chemistry | Cell Membrane - ultrastructure | Mitochondria - metabolism | Mitochondria - drug effects | Microscopy, Electron | Antiprotozoal Agents - pharmacology | Leishmania donovani - growth & development | Antiprotozoal Agents - isolation & purification | Enterococcus faecalis - metabolism | Cell Membrane Permeability - drug effects | Bacteriocins - pharmacology | Macrophages - drug effects | Bacteriocins - isolation & purification
Journal Article
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 11/2013, Volume 1828, Issue 11, pp. 2524 - 2531
Bacteriocin AS-48 is a membrane-interacting peptide that acts as a broad-spectrum antimicrobial against Gram-positive and Gram-negative bacteria. Prior Nuclear... 
AS-48 bacteriocin | Coarse-grained simulation | Antimicrobial peptide | MOLECULAR-DYNAMICS | CIRCULAR ENTEROCIN AS-48 | ANTIMICROBIAL PEPTIDES | MD SIMULATIONS | GRAM-NEGATIVE BACTERIA | LIPID-BILAYERS | PEPTIDE ANTIBIOTIC AS-48 | COMPUTER-SIMULATION | FORCE-FIELD | CELL-MEMBRANES | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOPHYSICS | Models | Chemical properties | Peptides | Analysis
Journal Article
Meat Science, ISSN 0309-1740, 2005, Volume 71, Issue 3, pp. 549 - 556
Results presented here are the first contribution on the anti-staphylococcal activity of bacteriocin AS-48 in a model meat sausage system. We have examined... 
Protective culture | Biopreservation | Sausage | Bacteriocin AS-48 | Staphylococcus aureus | LISTERIA-MONOCYTOGENES | FERMENTED SAUSAGE | protective culture | FOOD SCIENCE & TECHNOLOGY | bacteriocin AS-48 | sausage | FOODBORNE PATHOGENS | MEAT | ENTEROTOXIN PRODUCTION | biopreservation | PEPTIDE ANTIBIOTIC AS-48 | FAECALIS | CHEESE | CCM 4231 | Analysis
Journal Article
International Dairy Journal, ISSN 0958-6946, 2008, Volume 18, Issue 9, pp. 923 - 927
This study demonstrates the optimization of AS-48 production by strain Enterococcus faecalis A-48-32 using a whey-derived substrate, Esprion-300 (E-300). To... 
SAUSAGES | INHIBITION | BACTERIOCIN PRODUCTION | FOOD SCIENCE & TECHNOLOGY | PEPTIDE ANTIBIOTIC AS-48 | GROWTH | PURIFICATION | STAPHYLOCOCCUS-AUREUS | BACILLUS-CEREUS | Glucose metabolism | Glucose | Dextrose | Dairy industry
Journal Article