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Journal Article
Journal Article
Journal Article
New Phytologist, ISSN 0028-646X, 04/2019, Volume 222, Issue 1, pp. 159 - 170
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2018, Volume 57, Issue 52, pp. 17183 - 17188
Mitochondrial dysfunction is linked to a variety of human illnesses, but selective delivery of therapeutics into the mitochondrion is challenging. Now a family... 
cytosolic entry | drug delivery | cell-penetrating motif | mitochondrial targeting | PEPTIDES | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | PROBES | Cargo | Hsp90 protein | Heat shock proteins | Confocal microscopy | Hydrophobicity | Mammals | Mammalian cells | Anticancer properties | Proteins | Mitochondria | Naphthalene | Illnesses | Inhibitors | Microscopy | Benzene | Antitumor activity | Conjugation | Membrane potential | Viability | Heat shock
Journal Article
Biochemical Journal, ISSN 0264-6021, 10/2007, Volume 407, Issue 2, pp. 285 - 292
The use of CPPs (cell-penetrating peptides) as delivery vectors for bioactive molecules has been an emerging field since 1994 when the first CPP, penetratin,... 
Cytotoxicity | Penetratin | Transport | Delivery vector | Transactivator of transcription (Tat) | Cell-penetrating peptide | TAT-FUSION PROTEINS | TRANSPORTAN | ENTRY | MECHANISM | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | delivery vector | transport | transactivator of transcription (Tat) | cell-penetrating peptide | MAMMALIAN-CELLS | NUCLEIC-ACIDS | MACROPINOCYTOSIS | penetratin | cytotoxicity | DNA - pharmacokinetics | Carrier Proteins - toxicity | Cell Survival - drug effects | Wasp Venoms - therapeutic use | Galanin - therapeutic use | Proteins - pharmacokinetics | Galanin - toxicity | Gene Products, tat - therapeutic use | Humans | Recombinant Fusion Proteins - therapeutic use | Cell Membrane Permeability | DNA - administration & dosage | Recombinant Fusion Proteins - toxicity | Gene Products, tat - toxicity | Peptides - toxicity | Drug-Related Side Effects and Adverse Reactions | Proteins - administration & dosage | Wasp Venoms - toxicity | HeLa Cells | Carrier Proteins - therapeutic use | Drug Delivery Systems - methods | Drug Delivery Systems - adverse effects | Peptides - therapeutic use | Index Medicus | HOBt, 1-hydroxybenzotriazole | HKR, Hepes–Krebs–Ringer | t-Boc, t-butoxycarbonyl | TP10, transportan 10 | FBS, fetal bovine serum | LDH, lactate dehydrogenase | WST-1, water-soluble tetrazolium salt 1 | siRNA, small interfering RNA | Tat, transactivator of transcription | CHO, Chinese-hamster ovary | CPP, cell-penetrating peptide | dsDNA, double-stranded DNA | DMF, dimethylformamide | Neurochemistry | Basic Medicine | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICINE | Neurokemi | Chemistry | MEDICIN | Kemi | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2010, Volume 13, Issue 5, pp. 567 - 576
Continuous turnover of intracellular components by autophagy is necessary to preserve cellular homeostasis in all tissues. Alterations in macroautophagy, the... 
NEURODEGENERATIVE DISEASE | RAT-LIVER | MODELS | CHAPERONE-MEDIATED AUTOPHAGY | MONITORING AUTOPHAGY | MUTANT HUNTINGTIN | DEGRADATION | ALPHA-SYNUCLEIN | HD MUTATION | NEUROSCIENCES | CELL-DEATH | Serum - metabolism | Microscopy, Electron, Transmission - methods | Microtubule-Associated Proteins - metabolism | Humans | Huntington Disease - pathology | Peptides - genetics | Apoptosis - genetics | Autophagy - physiology | Hepatocytes - metabolism | Vinca Alkaloids - metabolism | Mitochondria - ultrastructure | Subcellular Fractions - pathology | Autophagy - drug effects | Subcellular Fractions - ultrastructure | Serotonin Plasma Membrane Transport Proteins - genetics | Lysosomes - metabolism | Neurons - ultrastructure | Time Factors | Neurons - drug effects | Immunosuppressive Agents - pharmacology | Hepatocytes - drug effects | Huntington Disease - physiopathology | Disease Models, Animal | Lysosomes - drug effects | Cells, Cultured | Enzyme Inhibitors - pharmacology | Mice, Transgenic | Mitochondria - pathology | Sirolimus - pharmacology | Subcellular Fractions - metabolism | Lysosomes - ultrastructure | Nerve Tissue Proteins - metabolism | Animals | Huntington Disease - genetics | Thapsigargin - pharmacology | Mice | Apoptosis - physiology | Autophagy (Cytology) | Gene mutations | Huntington's chorea | Cell death | Physiological aspects | Genetic aspects | Research | Index Medicus
Journal Article