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Nature, ISSN 0028-0836, 2013, Volume 494, Issue 7436, pp. 201 - 206
The lysosomal degradation pathway of autophagy has a crucial role in defence against infection, neurodegenerative disorders, cancer and ageing. Accordingly,... 
PATHOGENESIS | LOCALIZES | COMPLEX | PROTEIN | BECLIN-1 | PATHWAY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | DISEASE | INFECTION | BINDING | Apoptosis Regulatory Proteins - pharmacology | Recombinant Fusion Proteins - pharmacology | Humans | Cell Membrane Permeability | Molecular Sequence Data | Peptide Fragments - pharmacology | Membrane Proteins - pharmacology | Membrane Proteins - therapeutic use | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | HIV-1 - physiology | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | Beclin-1 | Amino Acid Sequence | HIV-1 - metabolism | Virus Replication - drug effects | Peptide Fragments - metabolism | HIV-1 - drug effects | tat Gene Products, Human Immunodeficiency Virus - genetics | Apoptosis Regulatory Proteins - chemistry | Cells, Cultured | West Nile virus - drug effects | Macrophages - cytology | Recombinant Fusion Proteins - chemistry | Apoptosis Regulatory Proteins - metabolism | Chikungunya virus - drug effects | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Mice | HeLa Cells | Apoptosis Regulatory Proteins - therapeutic use | tat Gene Products, Human Immunodeficiency Virus - metabolism | Proteins | Peptides | Microscopy | Rodents | Mortality | Amino acids | Infections | Autophagy | Index Medicus
Journal Article
2007, Ernst Schering Foundation symposium proceedings, ISBN 9783540489818, Volume 2006-2., xvii, 267
This book offers an insight into the approaches taken by industry and academia to address GPCRs and depict how mature this target class-oriented research has... 
Receptors | G proteins | Microbiology | Medical Microbiology | Medical Biochemistry | Biomedicine | Pharmacology/Toxicology | Computer Applications in Chemistry
Book
Journal Article
Nature Methods, ISSN 1548-7091, 08/2013, Volume 10, Issue 8, pp. 755 - 758
Current tandem mass spectral libraries for lipid annotations in metabolomics are limited in size and diversity. We provide a freely available... 
LIBRARIES | PLATFORM | BIOINFORMATICS | BIOCHEMICAL RESEARCH METHODS | TOOL | Lipids - analysis | Metabolomics - methods | Tandem Mass Spectrometry - methods | Databases, Factual | Lipids | Usage | Records and correspondence | Mass spectrometry | Identification and classification | Peptides | Metabolism | Genomics | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 03/2015, Volume 519, Issue 7542, pp. 237 - 241
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 2015, Volume 43, Issue 6, pp. 2993 - 3011
The ss-siRNA activity in vivo requires a metabolically stable 5 '-phosphate analog. In this report we used crystal structure of the 5 '-phosphate binding... 
RNA INTERFERENCE | TARGET | ANIMALS | PHOSPHONATE ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESTERS | CLEAVAGE | ANTISENSE OLIGONUCLEOTIDES | CHEMICAL-MODIFICATIONS | MAMMALIAN-CELLS | NUCLEIC-ACIDS | Index Medicus
Journal Article