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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2016, Volume 113, Issue 13, pp. E1890 - E1897
Journal Article
Methods in Enzymology, ISSN 0076-6879, 2019
Peptide major histocompatibility complex (pMHC) multimers have been used since decades to identify, isolate and analyze antigen-specific T cells by flow (and... 
CD4 | CD8 | Antigen discovery | Combinatorial | Tetramers | T cells | Peptide-MHC multimers
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2018, Volume 201, Issue 7, pp. 1817 - 1818
Journal Article
Nature Communications, ISSN 2041-1723, 12/2016, Volume 7, Issue 1, pp. 13848 - 13848
A robust primary immune response has been correlated with the precursor number of antigen-specific T cells, as identified using peptide MHCII tetramers.... 
RECEPTOR AFFINITY | TCR AFFINITY | REPERTOIRE DIVERSITY | CD8 CORECEPTOR | MULTIDISCIPLINARY SCIENCES | PEPTIDE-MHC | IN-VIVO | CROSS-REACTIVITY | CD4(+) T-CELLS | MEMORY CELLS | PRECURSOR FREQUENCY | Index Medicus
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 12/2014, Volume 111, Issue 49, pp. 17576 - 17581
alpha beta T-cell receptor (TCR) activation plays a crucial role for T-cell function. However, the TCR itself does not possess signaling domains. Instead, the... 
TCR | ACTIVATION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MAJOR HISTOCOMPATIBILITY COMPLEX | small-angle X-ray scattering | T-cell receptor | STRUCTURAL BASIS | ANTIGEN-RECEPTOR | PEPTIDE-MHC | electron microscopy | LIGAND | CD3-EPSILON-GAMMA HETERODIMER | CONSTANT-REGION
Journal Article
IMMUNITY, ISSN 1074-7613, 10/2011, Volume 35, Issue 4, pp. 526 - 535
alpha beta T cell receptors (TCRs) bind specifically to foreign antigens presented by major histocompatibility complex proteins (MHC) or MHC-like molecules.... 
ADAPTIVE IMMUNITY | NKT CELLS | AMINO-ACIDS | PEPTIDE-MHC | CLASS-I | NEGATIVE SELECTION | MAJOR HISTOCOMPATIBILITY COMPLEX | IMMUNOLOGY | ANTIGEN RECEPTOR | MHC RECOGNITION | BINDING
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 07/2008, Volume 9, Issue 7, pp. 777 - 784
It remains unclear whether gamma delta T cell antigen receptors (TCRs) detect antigens in a way similar to antibodies or alpha beta TCRs. Here we show that... 
COMPLEX | CD4 | CRYSTAL-STRUCTURE | ANTIGEN-SPECIFICITY | PEPTIDE-MHC | HIGH-AFFINITY | ANTIBODY | IMMUNOLOGY | RECEPTOR-DELTA | LYMPHOCYTES-T | REGION
Journal Article
Cell, ISSN 0092-8674, 01/2018, Volume 172, Issue 3, pp. 549 - 563.e16
Journal Article
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 01/2019, Volume 96, pp. 50 - 58
A primary initiating epitope in the NOD mouse model of Type 1 Diabetes (T1D) lies between residues 9 and 23 of the insulin B chain. The B:9-23 peptide can bind... 
CD8 T cell | Peptide/MHC | Monoclonal antibody | Chimeric antigen receptor | Type 1 diabetes | ADOPTIVE TRANSFER | RECOGNITION | AFFINITY | GENERATION | MICE | PEPTIDE REGISTER | IMMUNOLOGY
Journal Article