X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1195) 1195
biochemistry & molecular biology (531) 531
peptidyl transferase center (430) 430
peptidyl transferases - metabolism (395) 395
ribosomes - metabolism (349) 349
microbiology (326) 326
antibiotics (285) 285
molecular sequence data (283) 283
anti-bacterial agents - pharmacology (276) 276
penicillin-binding proteins (271) 271
binding sites (268) 268
models, molecular (255) 255
escherichia-coli (254) 254
base sequence (236) 236
humans (229) 229
peptidyl transferases (228) 228
nucleic acid conformation (212) 212
bacterial proteins (202) 202
proteins (193) 193
ribosomes - chemistry (186) 186
hexosyltransferases (183) 183
rna (181) 181
escherichia coli - genetics (179) 179
protein biosynthesis (179) 179
research (177) 177
ribosomes (172) 172
mutation (170) 170
pharmacology & pharmacy (170) 170
ribosome (170) 170
escherichia coli - metabolism (160) 160
peptidyl transferases - chemistry (151) 151
transfer-rna (151) 151
cell biology (145) 145
peptidyl transferases - genetics (144) 144
microbial sensitivity tests (141) 141
structural basis (139) 139
amino acid sequence (134) 134
bacteria (134) 134
kinetics (130) 130
protein binding (130) 130
crystal-structure (129) 129
animals (128) 128
carrier proteins - genetics (124) 124
muramoylpentapeptide carboxypeptidase - genetics (123) 123
bond formation (120) 120
translation (117) 117
rna, ribosomal, 23s - metabolism (115) 115
rna, ribosomal, 23s - genetics (114) 114
angstrom resolution (113) 113
protein-synthesis (112) 112
ribosomal proteins - metabolism (112) 112
subunit (112) 112
bacterial proteins - genetics (108) 108
ribosomes - drug effects (107) 107
ribosomes - genetics (107) 107
rna, transfer - metabolism (107) 107
rna, ribosomal, 23s - chemistry (106) 106
analysis (103) 103
peptidyl transferase (103) 103
structure-activity relationship (101) 101
anti-bacterial agents - chemistry (99) 99
resistance (99) 99
ribosomes - enzymology (99) 99
carrier proteins - metabolism (98) 98
peptides (98) 98
multidisciplinary sciences (96) 96
bacterial proteins - metabolism (95) 95
escherichia coli (94) 94
crystallography, x-ray (90) 90
biophysics (89) 89
catalysis (89) 89
ribonucleic acid--rna (89) 89
rna, ribosomal - metabolism (89) 89
biochemistry (88) 88
protein conformation (88) 88
muramoylpentapeptide carboxypeptidase - metabolism (87) 87
peptidyl-transferase center (87) 87
transfer rna (86) 86
physiological aspects (85) 85
genetic aspects (82) 82
23s ribosomal-rna (81) 81
article (80) 80
anti-bacterial agents - metabolism (79) 79
escherichia coli - enzymology (78) 78
binding (75) 75
rna, ribosomal - chemistry (75) 75
escherichia coli - drug effects (74) 74
rna, transfer, amino acyl - metabolism (74) 74
identification (72) 72
messenger-rna (71) 71
peptidyl transferases - antagonists & inhibitors (71) 71
ribosomal proteins - chemistry (70) 70
escherichia-coli ribosomes (68) 68
bacteriology (67) 67
nucleotides (67) 67
chloramphenicol (66) 66
protein synthesis (66) 66
ribosomal proteins - genetics (66) 66
staphylococcus aureus - drug effects (66) 66
molecular biology (65) 65
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nucleic Acids Research, ISSN 0305-1048, 02/2018, Volume 46, Issue 4, pp. 1945 - 1957
Abstract Intracellular levels of reactive oxygen species (ROS) increase as a consequence of oxidative stress and represent a major source of damage to... 
MESSENGER-RNA | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PEPTIDYL TRANSFERASE CENTER | ATOMIC MUTAGENESIS | BOND FORMATION | BASE-PAIRING PROPERTIES | REVERSE TRANSCRIPTASES | NASCENT PEPTIDE | PROTEIN-SYNTHESIS | TRANSLATION TERMINATION | Index Medicus | Nucleic Acid Enzymes
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2007, Volume 104, Issue 11, pp. 4291 - 4296
Journal Article
NATURE, ISSN 0028-0836, 04/2015, Volume 520, Issue 7548, pp. 567 - 567
Single particle electron cryomicroscopy (cryo-EM) has recently made significant progress in high-resolution structure determination of macromolecular complexes... 
REFINEMENT | ELONGATION-FACTOR TU | AMINOACYL-TRANSFER-RNA | MECHANISM | INITIATION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | PEPTIDYL TRANSFERASE CENTER | METHYLATIONS | RESISTANCE | TRANSLATION
Journal Article
FEBS Open Bio, ISSN 2211-5463, 2014, Volume 4, Issue 1, pp. 175 - 178
We tested the hypothesis of Tamura (2011) [3] that molecules of tRNA gave origin to ribosomes, particularly to the Peptidyl Transferase Center (PTC) of the 23S... 
Origin | Ribosome | tRNA | Peptidyl Transferase Center | TRNA | ANGSTROM RESOLUTION | LARGE RIBOSOMAL-SUBUNIT | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | TRANSLATION | EMERGENCE | WORLD | LIFE
Journal Article
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 07/2006, Volume 50, Issue 7, pp. 2500 - 2505
A novel multidrug resistance phenotype mediated by the Cfr rRNA methyltransferase is observed in Staphylococcus aureus and Escherichia coli. The cfr gene has... 
LINKING | CHLORAMPHENICOL | BACTERIAL RIBOSOME | MECHANISM | TIAMULIN | GENE | PEPTIDYL TRANSFERASE CENTER | MACROLIDE | FLORFENICOL | FEXA | MICROBIOLOGY | PHARMACOLOGY & PHARMACY
Journal Article
Journal of Physical Chemistry Letters, ISSN 1948-7185, 04/2012, Volume 3, Issue 8, pp. 1007 - 1010
Resistance mutations to antibiotics targeting rRNA can be far from the drug-binding site. Crystallography studies revealed that the antibiotic resistance... 
CATALYSIS | ANTIBIOTICS | PEPTIDYL-TRANSFERASE CENTER | RNA | CRYSTAL-STRUCTURE | MATERIALS SCIENCE, MULTIDISCIPLINARY | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | STRUCTURAL BASIS | RESISTANCE | MUTATIONS | BINDING
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2006, Volume 103, Issue 10, pp. 3598 - 3603
Studies in vitro have established that free tryptophan induces tna operon expression by binding to the ribosome that has just completed synthesis of... 
SITE | transcription termination | SPARSOMYCIN | MULTIDISCIPLINARY SCIENCES | BOND FORMATION | RELEASE | INDUCTION | TRANSLATION | tryptophanase operon | OPERON EXPRESSION | IN-VITRO | antibiotic inhibitors of translation | ESCHERICHIA-COLI K-12 | peptidyl transferase inhibition | tryptophan induction | TRANSFER-RNA
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 2017, Volume 139, Issue 38, pp. 13304 - 13307
Streptogramin antibiotics are used clinically to treat multidrug-resistant bacterial infections, but their poor physicochemical properties and narrow spectra... 
HALIDES | (-)-VIRGINIAMYCIN M-2 | CROSS-COUPLING REACTIONS | VIRGINIAMYCIN | (-)-MADUMYCIN II | PEPTIDYL TRANSFERASE CENTER | DALFOPRISTIN | CHEMISTRY, MULTIDISCIPLINARY | QUINUPRISTIN | Index Medicus
Journal Article