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PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e53791 - e53791
Protein Arginine Deiminases (PADs) catalyze the post-translational conversion of peptidyl-Arginine to peptidyl-Citrulline in a calcium-dependent, irreversible... 
CITRULLINATION | PAD4 | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | PEPTIDYLARGININE DEIMINASE | GENE-EXPRESSION | DOWN-REGULATION | INACTIVATORS | SUPPRESSION | MIR-16 FAMILY | P53 | Colonic Neoplasms - genetics | Hydrolases - genetics | Colonic Neoplasms - drug therapy | Humans | MicroRNAs - metabolism | G1 Phase - drug effects | Enzyme Inhibitors - chemical synthesis | Cyclin E - genetics | Colonic Neoplasms - metabolism | Tumor Suppressor Protein p53 - genetics | Protein Isoforms - metabolism | Tumor Suppressor Protein p53 - agonists | Cell Cycle Checkpoints - genetics | G1 Phase - genetics | Gene Expression Regulation, Neoplastic - drug effects | Amidines - chemical synthesis | Hydrolases - metabolism | Signal Transduction | Cyclin-Dependent Kinase 6 - genetics | Enzyme Inhibitors - pharmacology | Tumor Suppressor Protein p53 - metabolism | Cyclin-Dependent Kinase 6 - metabolism | Cell Cycle Checkpoints - drug effects | Colonic Neoplasms - pathology | Cell Line, Tumor | Amidines - pharmacology | MicroRNAs - genetics | Cyclin E - metabolism | Cyclin D - genetics | Cyclin D - metabolism | Protein-Arginine Deiminases | Hydrolases - antagonists & inhibitors | Protein Isoforms - genetics | Colon cancer | MicroRNA | Arginine | Tumor proteins | Cancer cells | Cell cycle | Cell culture | Calcium | Laboratories | p53 Protein | Colorectal cancer | Kinases | Carcinogenesis | Arginine deiminase | Proteins | Carcinogens | Penicillin | Post-translation | Colon | Inhibition | Chronic illnesses | Medical research | Enzymes | Research & development--R&D | MiRNA | Citrulline | Mammals | Gene expression | Cyclins | Inflammatory bowel disease | Ribonucleic acids | MicroRNAs | Pharmacy | Tumor suppressor genes | Cancer | Apoptosis | Index Medicus | RNA | Research & development | miRNA | Ribonucleic acid | R&D
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 05/2017, Volume 188, Issue 2, pp. 263 - 274
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 02/2018, Volume 18, Issue 2, pp. 134 - 147
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2016, Volume 22, Issue 2, pp. 146 - 153
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 08/2018, Volume 833, pp. 432 - 440
Immune cell death caused by neutrophil extracellular traps (NETs), referred to as NETosis, can contribute to the pathogenesis of endotoxemia and organ damage.... 
Lipopolysaccharide | Peptidylarginine deiminase | Citrullinated histone H3 | Neutrophil extracellular traps | Microvascular permeability | TARGET | NETTING NEUTROPHILS | CL-AMIDINE | ACUTE LUNG INJURY | SEPSIS | IN-VIVO | SEPTIC SHOCK | PHARMACOLOGY & PHARMACY | Endothelium, Vascular - cytology | Human Umbilical Vein Endothelial Cells | Extracellular Traps - metabolism | Humans | Microvessels - metabolism | Endotoxemia - chemically induced | Microvessels - pathology | Endothelium, Vascular - drug effects | Arginine - analogs & derivatives | Extracellular Traps - drug effects | 2-Naphthylamine - therapeutic use | Acute Lung Injury - drug therapy | Neutrophils - metabolism | Disease Models, Animal | Microvessels - cytology | Lung - pathology | Permeability - drug effects | 2-Naphthylamine - pharmacology | Lipopolysaccharides - toxicity | Endotoxemia - drug therapy | Mice, Inbred C57BL | Neutrophils - drug effects | Microvessels - drug effects | Treatment Outcome | Acute Lung Injury - pathology | Protein-Arginine Deiminases - metabolism | 2-Naphthylamine - analogs & derivatives | Animals | Endothelium, Vascular - metabolism | Endotoxemia - complications | Arginine - pharmacology | Endothelium, Vascular - pathology | Mice | Histones - metabolism | Arginine - therapeutic use | Endothelial Cells - pathology | Endotoxemia - mortality | Lung - blood supply | Acute Lung Injury - etiology | Citrullination - drug effects | Endothelial Cells - drug effects | Protein-Arginine Deiminases - antagonists & inhibitors | Acute respiratory distress syndrome | Cell death | Analysis | Permeability | Mitogens | Health aspects | Endothelium
Journal Article