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Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, p. 20254
Tumor cell-derived exosomes (TEX) suppress functions of immune cells. Here, changes in the gene profiles of primary human T lymphocytes exposed in vitro to... 
MESSENGER-RNAS | CANCER-PATIENTS | EXTRACELLULAR VESICLES | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | MICROVESICLES | DIAGNOSTIC BIOMARKERS | INDUCE APOPTOSIS | OVARIAN-CANCER | MODULATION | LYMPHOCYTES | Exosomes - metabolism | Neoplasms - metabolism | CD8-Positive T-Lymphocytes - cytology | T-Lymphocytes, Regulatory - metabolism | T-Lymphocyte Subsets - cytology | Humans | Culture Media, Conditioned - pharmacology | RNA, Messenger - metabolism | Antigens, CD - metabolism | Lectins, C-Type - metabolism | T-Lymphocyte Subsets - drug effects | T-Lymphocytes, Regulatory - cytology | CD8-Positive T-Lymphocytes - metabolism | Real-Time Polymerase Chain Reaction | Microscopy, Electron, Transmission | CD4-Positive T-Lymphocytes - cytology | Apyrase - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Antigens, Differentiation, T-Lymphocyte - metabolism | Down-Regulation - drug effects | Up-Regulation - drug effects | T-Lymphocytes, Regulatory - drug effects | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | Adenosine - metabolism | Neoplasms - pathology | CD4-Positive T-Lymphocytes - drug effects | Microscopy, Fluorescence | Adenosine | Dendritic cells | CD8 antigen | Gene regulation | Data processing | T cell receptors | Lymphocytes T | Gene expression | Exosomes | Cell surface | CD4 antigen | Polymerase chain reaction | CD69 antigen | Cell activation | Lymphocytes | Down-regulation | Peripheral blood
Journal Article
British Journal of Haematology, ISSN 0007-1048, 07/2017, Volume 178, Issue 2, pp. 292 - 301
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 6/2010, Volume 201, Issue 12, pp. 1923 - 1932
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 31, pp. 12833 - 12838
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2017, Volume 127, Issue 9, pp. 3462 - 3471
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13, pp. 3604 - 3618
The production of CD73-derived a denosine (Ado) by Tregs has been proposed as a resistance mechanism to anti-PD-1 therapy in murine tumor models. We reported... 
BREAST-CANCER | CD73 | T(H)17 CELLS | METASTASIS | HUMAN PERIPHERAL-BLOOD | ONCOLOGY | TNF-ALPHA | SUPPRESSION | EXPRESSION | PROMOTES | TH17 CELLS | T-Lymphocytes, Regulatory - metabolism | Breast Neoplasms - immunology | Humans | Ovarian Neoplasms - pathology | T-Lymphocytes, Regulatory - immunology | T-Lymphocytes, Helper-Inducer - immunology | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Costimulatory and Inhibitory T-Cell Receptors - antagonists & inhibitors | Ovarian Neoplasms - drug therapy | Tumor Escape - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Apyrase - metabolism | Drug Resistance, Neoplasm - immunology | Breast Neoplasms - drug therapy | GPI-Linked Proteins - metabolism | Antineoplastic Agents, Immunological - pharmacology | Interleukin-17 - metabolism | Antineoplastic Agents, Immunological - therapeutic use | Breast Neoplasms - pathology | Costimulatory and Inhibitory T-Cell Receptors - metabolism | Adenosine - metabolism | 5'-Nucleotidase - metabolism | Lymphocytes, Tumor-Infiltrating - immunology | Ovarian Neoplasms - immunology | Therapy | Animal models | PD-1 protein | Effector cells | Interleukin 22 | Lymphocytes T | Immunity | MDR1 protein | Lymphocytes | Interleukin 1 | CD73 antigen | Autocrine signalling | Biodegradation | Adenosine | AMP | Granulocyte-macrophage colony-stimulating factor | Breast cancer | CXCR3 protein | CCR6 protein | CD4 antigen | Immune checkpoint | γ-Interferon | Effectors | Breast | Ectonucleotidase | ATP | Adenosine triphosphatase | Cancer | Tumors | Life Sciences | Human health and pathology
Journal Article