X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
malaria (352) 352
humans (326) 326
pfmdr1 gene (297) 297
plasmodium falciparum - genetics (294) 294
plasmodium falciparum - drug effects (292) 292
index medicus (291) 291
drug resistance (270) 270
plasmodium falciparum (269) 269
antimalarials - pharmacology (266) 266
animals (235) 235
parasitology (217) 217
pfmdr1 (202) 202
parasitic diseases (200) 200
tropical medicine (185) 185
protozoan proteins - genetics (182) 182
malaria, falciparum - parasitology (176) 176
malaria, falciparum - drug therapy (170) 170
infectious diseases (168) 168
drug resistance - genetics (150) 150
chloroquine resistance (143) 143
parasites (142) 142
chloroquine (140) 140
mutation (140) 140
antimalarials - therapeutic use (135) 135
pfcrt (130) 130
research (130) 130
mutations (128) 128
chloroquine - pharmacology (117) 117
artemether-lumefantrine (114) 114
mefloquine (111) 111
microbiology (106) 106
polymerase chain reaction (105) 105
multidrug resistance-associated proteins - genetics (104) 104
female (102) 102
male (101) 101
mefloquine resistance (98) 98
child (97) 97
antimalarials (94) 94
drug-resistance (94) 94
sensitivity (94) 94
artemisinins - pharmacology (90) 90
in-vitro (88) 88
artemisinin (87) 87
child, preschool (84) 84
plasmodium falciparum - isolation & purification (84) 84
membrane transport proteins - genetics (83) 83
genetic aspects (78) 78
malaria, falciparum - epidemiology (77) 77
adult (76) 76
pharmacology & pharmacy (74) 74
genotype (73) 73
polymorphism, genetic (72) 72
alleles (71) 71
genes (68) 68
adolescent (67) 67
amplification (67) 67
artemisinins - therapeutic use (66) 66
public, environmental & occupational health (66) 66
resistance (65) 65
dihydrofolate-reductase (64) 64
haplotypes (63) 63
infectious and parasitic diseases (62) 62
infant (61) 61
plasmodium-falciparum (61) 61
polymorphisms (60) 60
plasmodium-falciparum malaria (59) 59
artemisinin resistance (58) 58
amodiaquine (57) 57
malaria parasites (56) 56
copy number (55) 55
susceptibility (55) 55
chloroquine-resistance (54) 54
gene (54) 54
parasitic sensitivity tests (54) 54
erythrocytes (53) 53
sulfadoxine-pyrimethamine (53) 53
arctic medicine. tropical medicine (52) 52
chloroquine - therapeutic use (52) 52
multidrug-resistance (52) 52
drug resistance in microorganisms (51) 51
drug therapy (51) 51
vector-borne diseases (49) 49
drug combinations (48) 48
biochemistry & molecular biology (47) 47
dna, protozoan - genetics (47) 47
gene dosage (47) 47
health aspects (47) 47
mefloquine - pharmacology (47) 47
polymorphism, single nucleotide (47) 47
pyrimethamine (47) 47
analysis (45) 45
prevalence (44) 44
studies (44) 44
drugs (42) 42
point mutations (42) 42
protozoan proteins - metabolism (42) 42
artesunate (41) 41
thailand (41) 41
point mutation (40) 40
middle aged (39) 39
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


by Venkatesan, Meera and Gadalla, Nahla B and Stepniewska, Kasia and Dahal, Prabin and Nsanzabana, Christian and Moriera, Clarissa and Price, Ric N and Ma˚rtensson, Andreas and Rosenthal, Philip J and Dorsey, Grant and Sutherland, Colin J and Guérin, Philippe and Davis, Timothy M. E and Ménard, Didier and Adam, Ishag and Ademowo, George and Arze, Cesar and Baliraine, Frederick N and Berens-Riha, Nicole and Björkman, Anders and Borrmann, Steffen and Checchi, Francesco and Desai, Meghna and Dhorda, Mehul and Djimdé, Abdoulaye A and El-Sayed, Badria B and Eshetu, Teferi and Eyase, Frederick and Falade, Catherine and Faucher, Jean-Franc¸ois and Fröberg, Gabrielle and Grivoyannis, Anastasia and Hamour, Sally and Houzé, Sandrine and Johnson, Jacob and Kamugisha, Erasmus and Kariuki, Simon and Kiechel, Jean-René and Kironde, Fred and Kofoed, Poul-Erik and LeBras, Jacques and Malmberg, Maja and Mwai, Leah and Ngasala, Billy and Nosten, Francois and Nsobya, Samuel L and Nzila, Alexis and Oguike, Mary and Otienoburu, Sabina Dahlström and Ogutu, Bernhards and Ouédraogo, Jean-Bosco and Piola, Patrice and Rombo, Lars and Schramm, Birgit and Somé, A. Fabrice and Thwing, Julie and Ursing, Johan and Wong, Rina P. M and Zeynudin, Ahmed and Zongo, Issaka and Plowe, Christopher V and Sibley, Carol Hopkins and WWARN AL & ASAQ Mol Marker Study and ASAQ Molecular Marker Study Group and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Centrum för klinisk forskning i Sörmland (CKFD)
American Journal of Tropical Medicine and Hygiene, ISSN 0002-9637, 10/2014, Volume 91, Issue 4, pp. 833 - 843
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the... 
PLUS SULFADOXINE-PYRIMETHAMINE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | PLASMODIUM-FALCIPARUM-PFMDR1 ALLELES | DIHYDROARTEMISININ-PIPERAQUINE | IN-VIVO | TANZANIAN CHILDREN | PFMDR1 COPY NUMBER | UNCOMPLICATED MALARIA | COMBINATION THERAPIES | DRUG-RESISTANCE | TYROSINE-86 ALLELE | TROPICAL MEDICINE | Humans | Fluorenes - therapeutic use | Child, Preschool | Infant | Plasmodium falciparum - drug effects | Protozoan Proteins - genetics | Chloroquine - pharmacology | Membrane Transport Proteins - genetics | Plasmodium falciparum - genetics | Multidrug Resistance-Associated Proteins - genetics | Amodiaquine - therapeutic use | Drug Therapy, Combination | Child | Malaria, Falciparum - drug therapy | Datasets as Topic | Risk Factors | Kaplan-Meier Estimate | Genotype | Antimalarials - therapeutic use | Antimalarials - pharmacology | Polymorphism, Genetic | Drug Resistance - genetics | Malaria, Falciparum - parasitology | Artemisinins - therapeutic use | Genetic Markers - genetics | Artemether | Ethanolamines - therapeutic use | Lumefantrine | Drug Combinations | Amino Acid Substitution | Malaria, Falciparum | Chloroquine | Fluorenes | Antimalarials | Protozoan Proteins | Life Sciences | Plasmodium falciparum | Drug Resistance | Pharmaceutical sciences | Parasitology | Pharmacology | Genetic Markers | Ethanolamines | Human health and pathology | Microbiology and Parasitology | Infectious diseases | Artemisinins | Membrane Transport Proteins | Amodiaquine | Multidrug Resistance-Associated Proteins
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2008, Volume 3, Issue 6, pp. e2484 - e2484
Mutations in PfCRT (Plasmodium falciparum chloroquine-resistant transporter), particularly the substitution at amino acid position 76, confer chloroquine (CQ)... 
LINKAGE DISEQUILIBRIUM | MULTIDISCIPLINARY SCIENCES | ANTIBIOTIC-RESISTANCE | SENSITIVITY | MEFLOQUINE RESISTANCE | CHLOROQUINE-RESISTANCE TRANSPORTER | QUININE | TRANSMEMBRANE PROTEIN PFCRT | PFMDR1 GENE | MALARIA PARASITES | DIGESTIVE VACUOLAR PH | Up-Regulation | Genome, Protozoan | RNA, Messenger - genetics | Gene Expression Profiling | Protozoan Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Antimalarials - pharmacology | Chloroquine - pharmacology | Animals | Membrane Transport Proteins - genetics | Gene Deletion | Plasmodium falciparum - genetics | Mutation | Drug Evaluation, Preclinical | Hydrogen-Ion Concentration | Proteins | Plasmodium falciparum | Drug resistance in microorganisms | Gene mutations | Malaria | Genomics | Cellular signal transduction | Genomes | Gene expression | Adaptations | Cell culture | Transcription | Calcium | Laboratories | Hydrogen | Copy number | Chloroquine | Genes | Erythrocytes | Homology | Hybridization | Parasites | Drug resistance | pH effects | Amino acid substitution | Food vacuoles | Chromosomes | Bioinformatics | Pyrophosphatase | Deoxyribonucleic acid--DNA | Parasitology | Multidrug resistance | Ribonucleic acid--RNA | Mutants | Pfcrt gene | Infectious diseases | Microscopy | Transduction | Transport | Transporter | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Malaria Journal, ISSN 1475-2875, 2013, Volume 12, Issue 1, pp. 377 - 377
Background: With the introduction of artemisinin-based combination therapy (ACT) in 2005, monitoring of anti-malarial drug efficacy, which includes the use of... 
Molecular markers | Plasmodium falciparum multidrug resistance gene (pfmdr1) | Anti-malarial drug resistance | Ghana | Plasmodium falciparum chloroquine resistance transporter gene (pfcrt) | INFECTIOUS DISEASES | CHLOROQUINE-RESISTANCE | ARTEMETHER-LUMEFANTRINE | TYROSINE-86 ALLELE | TROPICAL MEDICINE | IN-VITRO | TRANSPORTER GENE | UNCOMPLICATED MALARIA | MULTIDRUG-RESISTANCE | SELECTION | PARASITOLOGY | AMODIAQUINE RESISTANCE | Humans | Child, Preschool | Infant | Male | Mutation, Missense | Plasmodium falciparum - drug effects | Protozoan Proteins - genetics | Plasmodium falciparum - classification | Membrane Transport Proteins - genetics | Plasmodium falciparum - genetics | Plasmodium falciparum - isolation & purification | Malaria, Falciparum - epidemiology | Female | Multidrug Resistance-Associated Proteins - genetics | Health Policy | Real-Time Polymerase Chain Reaction | Drug Resistance | Gene Frequency | Antimalarials - therapeutic use | Gene Dosage | Antimalarials - pharmacology | Ghana - epidemiology | Malaria, Falciparum - parasitology | Polymorphism, Restriction Fragment Length | DNA, Protozoan - genetics | Allelomorphism | Drug resistance in microorganisms | Genetic markers | Gene mutations | Malaria | Children | Drug resistance | Genetic polymorphisms | Diseases | Studies | Haplotypes | Chemotherapy | Gene amplification | Womens health | Parasitic diseases | Mutation | Parasites | Gene expression | Epidemiology
Journal Article
Parasitology Research, ISSN 0932-0113, 10/2019, Volume 118, Issue 10, pp. 3085 - 3089
Multidrug resistance in Plasmodium falciparum has been associated with gene amplification of pfmdr1. We studied the corresponding gene amplification in P.... 
Medical Microbiology | Venezuela | Biomedicine | Immunology | Microbiology | Malaria | P. falciparum | pfmdr1 gene | SUSCEPTIBILITY | SENSITIVITY | DRUG-RESISTANCE | MEFLOQUINE | MALARIA PARASITES | LUMEFANTRINE | CHLOROQUINE RESISTANCE | PLASMODIUM-FALCIPARUM | COPY NUMBER | MUTATIONS | PARASITOLOGY | falciparum
Journal Article
Malaria journal, ISSN 1475-2875, 10/2018, Volume 17, Issue 1, pp. 398 - 12
Journal Article
Malaria Journal, ISSN 1475-2875, 08/2016, Volume 15, Issue 1, p. 433
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, p. e20212
Chemotherapy is a critical component of malaria control. However, the most deadly malaria pathogen, Plasmodium falciparum, has repeatedly mounted resistance... 
IN-VIVO SELECTION | SUBSTRATE-SPECIFICITY | ARTEMISININ RESISTANCE | ARTEMETHER-LUMEFANTRINE | COMBINATION THERAPY | AMINO-ACIDS | BIOLOGY | PFMDR1 COPY NUMBER | MEFLOQUINE RESISTANCE | MALARIA PARASITE | CHLOROQUINE RESISTANCE | Haplotypes | Mefloquine - pharmacology | Ethanolamines - pharmacology | Malaria, Falciparum - drug therapy | Gene Frequency | Humans | Genotype | Fluorenes - pharmacology | Plasmodium falciparum - drug effects | Protozoan Proteins - genetics | Antimalarials - pharmacology | Drug Resistance - genetics | Malaria, Falciparum - parasitology | Artemisinins - pharmacology | Animals | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | Base Sequence | Plasmodium falciparum - genetics | Inhibitory Concentration 50 | Multidrug Resistance-Associated Proteins - genetics | Polymorphism, Single Nucleotide | Drug resistance in microorganisms | Plasmodium falciparum | Chemotherapy | Malaria | Earthquakes | Genes | Antimalarials | Disease susceptibility | Genetic polymorphisms | Cancer | Membrane proteins | Quinolines | Bioengineering | Drugs | Biotechnology | Copy number | Artemisinin | Single-nucleotide polymorphism | Parasites | Drug resistance | Alcohols | Proteins | 21st century | Parasitic diseases | ABC transporters | Organic compounds | Dihydroartemisinin | Vector-borne diseases | Enzymes | Pfmdr1 gene | Mefloquine | Multidrug resistance | Medicine | Transporter | ABC transporter
Journal Article
Molecular Biology and Evolution, ISSN 0737-4038, 2/2007, Volume 24, Issue 2, pp. 562 - 573
Journal Article
Journal Article