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PLOS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10
Transmission-blocking vaccines (TBVs) that target sexual stage parasite development could be an integral part of measures for malaria elimination. Pfs25 is a... 
AERUGINOSA EXOPROTEIN-A | EFFICACY | MOSQUITOS | MEMBRANE-FEEDING ASSAY | MULTIDISCIPLINARY SCIENCES | PFS25 | CANDIDATES | CHILDREN
Journal Article
Analytical Biochemistry, ISSN 0003-2697, 02/2018, Volume 542, pp. 20 - 23
A liquid chromatography tandem-mass spectrometry method was developed to map the eleven disulfide bonds in Pfs25, a malaria transmission-blocking vaccine... 
Plasmodium falciparum | Malaria | Baculovirus | Pfs25 | Disulfide | ANTIBODIES | CHEMISTRY, ANALYTICAL | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | ANTIGENS | PLASMODIUM-FALCIPARUM | PICHIA-PASTORIS | EXPRESSION
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 10/2019, Volume 10
Malaria parasites undergo several stages in their complex lifecycle. To achieve reductions in both the individual disease burden and malaria transmission... 
IMMUNE-RESPONSE | SAFETY | human adenovirus serotype 5 | adeno-associated virus | NYVAC-PF7 | IMMUNOLOGY | multi-stage malaria vaccine | TRIAL | CHALLENGE | MULTIANTIGEN | Pfs25 | transmission-blocking | Plasmodiumfalciparum circumsporozoite protein | CANDIDATES | Plasmodium falciparum circumsporozoite protein
Journal Article
Chinese Journal of New Drugs, ISSN 1003-3734, 07/2014, Volume 23, Issue 14, pp. 1622 - 1627
Journal Article
Journal Article
Journal Article
Nature Nanotechnology, ISSN 1748-3387, 12/2018, Volume 13, Issue 12, pp. 1174 - 1181
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 28, pp. 2954 - 2962
Highlights • Pfs25 is candidate for a malaria transmission blocking vaccine. • A recombinant Pfs25 protein was chemically cross-linked to ExoProtein A (EPA). •... 
Allergy and Immunology | Transmission blocking vaccine | Recombinant protein | Malaria | Chemical-conjugate | Nanoparticle | Pfs25 | CRYSTALLIZATION | MEDICINE, RESEARCH & EXPERIMENTAL | SURFACE-PROTEINS | MEMBRANE-PROTEIN | ANTIBODY | CANDIDATE | IMMUNOLOGY | RESPONSES | IMMUNOGENICITY | PEPTIDES | PLASMODIUM-FALCIPARUM | SECONDARY STRUCTURE ANALYSES | Malaria, Falciparum - prevention & control | Aluminum Hydroxide | Humans | Vaccination | Virulence Factors - immunology | Plasmodium falciparum - immunology | Malaria Vaccines - chemistry | Nanoparticles | Malaria, Falciparum - transmission | Vaccines, Conjugate - immunology | Malaria Vaccines - immunology | Vaccines, Conjugate - chemistry | Female | Protozoan Proteins - chemistry | Pseudomonas aeruginosa | ADP Ribose Transferases - chemistry | ADP Ribose Transferases - immunology | Exotoxins - chemistry | Bacterial Toxins - immunology | Exotoxins - immunology | Recombinant Proteins - chemistry | Virulence Factors - chemistry | Bacterial Toxins - chemistry | Animals | Recombinant Proteins - immunology | Malaria, Falciparum - immunology | Protein Conformation | Mice | Protozoan Proteins - immunology | Proteins | Peptides | Research & development--R&D | Amino acids | Vaccines | Methods | Crystal structure | nanoparticle | chemical-conjugate | malaria | transmission blocking vaccine | recombinant protein
Journal Article
Vaccine, ISSN 0264-410X, 09/2018, Volume 36, Issue 39, pp. 5865 - 5871
Malaria continues to be one of the world’s most devastating infectious tropical diseases, and alternative strategies to prevent infection and disease spread... 
Transmission blocking vaccine | Virus-like particle | Plant-produced | Malaria | Pfs25 | MEDICINE, RESEARCH & EXPERIMENTAL | PROTEIN | SEXUAL STAGES | STAGE | CANDIDATE | ANTIGENS | IMMUNOLOGY | AERUGINOSA EXOPROTEIN-A | PLASMODIUM-FALCIPARUM | PICHIA-PASTORIS | ANTIBODY-RESPONSES | EXPRESSION | Immunogenicity, Vaccine | Malaria, Falciparum - prevention & control | Adjuvants, Immunologic - administration & dosage | Antigens, Protozoan - immunology | Tobacco - metabolism | Humans | Middle Aged | Male | Vaccines, Synthetic - immunology | Healthy Volunteers | Young Adult | Plasmodium falciparum | Antibodies, Protozoan - blood | Vaccines, Synthetic - adverse effects | Malaria Vaccines - adverse effects | Adolescent | Malaria Vaccines - immunology | Alfalfa mosaic virus | Adult | Female | Vaccines, Virus-Like Particle - immunology | Protozoan Proteins - immunology | Proteins | Medical research | Disease transmission | Vaccination | Malaria vaccine | Clinical trials | Medicine, Experimental | Adults | Vaccines | Health aspects | Gametes | Toxicity | Midgut | Immunoglobulin G | Hispanic Americans | Antibodies | Viruses | Parasites | Family medical history | Disease spread | Aquatic insects | Virus-like particles | Coat protein | Safety | Plant viruses | Drug dosages | Vector-borne diseases | Antigens | Alfalfa | Plants | Sexual stages | Plant virus diseases | Zygotes | Mosquitoes | Immunogenicity | Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 2010, Volume 28, Issue 27, pp. 4423 - 4429
Abstract Plasmodium falciparum surface protein 25 (Pfs25) is a candidate for transmission-blocking vaccines (TBVs). Anti-Pfs25 antibodies block the development... 
Allergy and Immunology | Vaccine development | Plasmodium falciparum | Transmission-blocking vaccine | MEDICINE, RESEARCH & EXPERIMENTAL | PROTEIN | PLASMODIUM-FALCIPARUM INFECTION | PFS25 | CANDIDATE | IMMUNOLOGY | MALARIA TRANSMISSION | AREA | GAMETOCYTE INFECTIVITY | SEXUAL STAGE | HUMAN-POPULATIONS | Mosquitoes | Immunization | Parasites | Malaria
Journal Article