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Molecular Cell, ISSN 1097-2765, 11/2019, Volume 76, Issue 3, pp. 516 - 527.e7
The PTEN tumor suppressor is frequently mutated or deleted in cancer and regulates glucose metabolism through the PI3K-AKT pathway. However, whether PTEN... 
PTEN | PGK1 | tumorigenesis | autophosphorylation | glycolysis
Journal Article
Iranian Journal of Biotechnology, ISSN 2322-2921, 06/2019, Volume 17, Issue 2, pp. 38 - 45
Journal Article
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, ISSN 1000-6834, 04/2017, Volume 33, Issue 4, pp. 289 - 293
Journal Article
Genes, ISSN 2073-4425, 10/2019, Volume 10, Issue 10, p. 785
Phosphoglycerate kinase (PGK)1 deficiency is an X-linked inherited disease associated with different clinical presentations, sometimes as myopathic affectation... 
myopathic form | abnormalities in mRNA splicing | phosphoglycerate kinase 1 gene (PGK1) | missense variant | PGK1 deficiency
Journal Article
Autophagy, ISSN 1554-8627, 07/2017, Volume 13, Issue 7, pp. 1246 - 1247
Macroautophagy/autophagy is a cellular defense response to stress conditions and is crucial for cell homeostasis maintenance. However, the precise mechanism... 
ARD1 | autophagy | tumor | Beclin 1 | PGK1 | VPS34 | phosphorylation | MTOR | protein kinase | CELL BIOLOGY
Journal Article
International Journal of Surgery, ISSN 1743-9191, 2015, Volume 22, pp. 92 - 98
Journal Article
Autophagy, ISSN 1554-8627, 07/2017, Volume 13, Issue 7, pp. 1091 - 1092
When it comes to cancer initiation and progression, macroautophagy/autophagy seemingly acts in a contradictory fashion, serving either as a suppressive factor... 
PGK1 | BECN1 | stress | cancer | autophagy | glutamine | CELL BIOLOGY | Phosphoglycerate Kinase | Beclin-1 - genetics | Phosphorylation | Autophagy | Carcinogenesis | Humans
Journal Article
Molecular cell, ISSN 1097-2765, 3/2016, Volume 61, Issue 5, pp. 705 - 719
It is unclear how the Warburg effect that exemplifies enhanced glycolysis in the cytosol is coordinated with suppressed mitochondrial pyruvate metabolism. We... 
hypoxia | K-Ras | PDH | mitochondria | glycolysis | PGK1 | B-Raf | tumorigenesis | PDHK1 | phosphorylation | EGFR
Journal Article
Journal of Inherited Metabolic Disease, ISSN 0141-8955, 09/2019, Volume 42, Issue 5, pp. 803 - 808
Phosphoglycerate kinase (PGK) deficiency is a rare X‐linked metabolic disorder caused by mutations in the PGK1 gene. Patients usually develop various... 
PGK deficiency | PGK1 gene | parkinsonism | myopathy | polyneuropathy | MEDICINE, RESEARCH & EXPERIMENTAL | 2 BROTHERS | VARIANT | PGK CRETEIL | MUTATION | ENDOCRINOLOGY & METABOLISM | GENETICS & HEREDITY | MYOPATHIC FORM
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2017, Volume 65, Issue 5, pp. 917 - 931.e6
Autophagy is crucial for maintaining cell homeostasis. However, the precise mechanism underlying autophagy initiation remains to be defined. Here, we... 
ARD1 | autophagy | tumor | PGK1 | mTOR | Beclin1 | VPS34 | BREAST-CANCER | NUCLEOTIDE SYNTHESIS | METABOLISM | SIGNALING PATHWAY | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHATIDYLINOSITOL 3-KINASE COMPLEXES | GROWTH | TUMOR-CELLS | BETA-CATENIN | TUMORIGENESIS | CELL BIOLOGY | Glioblastoma - enzymology | Glutamine - deficiency | Phosphorylation | Cell Proliferation | TOR Serine-Threonine Kinases - metabolism | Humans | Autophagosomes - enzymology | Brain Neoplasms - pathology | Autophagy | Tumor Hypoxia | TOR Serine-Threonine Kinases - genetics | Transfection | Glioblastoma - genetics | RNA Interference | Time Factors | HEK293 Cells | Female | Acetylation | Phosphoglycerate Kinase - genetics | Brain Neoplasms - enzymology | Signal Transduction | N-Terminal Acetyltransferase A - genetics | Brain Neoplasms - genetics | Class III Phosphatidylinositol 3-Kinases - metabolism | Tumor Burden | Autophagosomes - pathology | Animals | N-Terminal Acetyltransferase A - metabolism | Class III Phosphatidylinositol 3-Kinases - genetics | Mice, Nude | Glioblastoma - pathology | Beclin-1 - genetics | Cell Line, Tumor | N-Terminal Acetyltransferase E - genetics | Protein Binding | Beclin-1 - metabolism | N-Terminal Acetyltransferase E - metabolism | Phosphoglycerate Kinase - metabolism | Enzymes | Medical colleges | Gliomas | Pancreatic cancer | Brain tumors | Physiological aspects | Phospholipids | Protein kinases | Glutamine
Journal Article
Molecular Cell, ISSN 1097-2765, 07/2018, Volume 71, Issue 2, pp. 201 - 215.e7
Macrophages are a dominant leukocyte population in the tumor microenvironment and actively promote cancer progression. However, the molecular mechanism... 
PGK1 | macrophage | tumorigenesis | aerobic glycolysis | CELLS | MICROENVIRONMENT | PKM2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-ASSOCIATED MACROPHAGES | PHOSPHOGLYCERATE KINASE | BLOOD-BRAIN-BARRIER | CANCER | EXPRESSION | PDK1 | CELL BIOLOGY | Glucose metabolism | Interleukins | Gliomas | Analysis | Physiological aspects | Development and progression | Macrophages | Protein kinases
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2016, Volume 61, Issue 5, pp. 705 - 719
It is unclear how the Warburg effect that exemplifies enhanced glycolysis in the cytosol is coordinated with suppressed mitochondrial pyruvate metabolism. We... 
hypoxia | K-Ras | PDH | mitochondria | glycolysis | PGK1 | B-Raf | tumorigenesis | PDHK1 | phosphorylation | EGFR | Mitochondria | Phosphorylation | Glycolysis | Hypoxia | Tumorigenesis | PYRUVATE-DEHYDROGENASE KINASE | HISTONE H3 | PKM2 | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | HYPOXIA | CANCER | PROMOTES | HUMAN PHOSPHOGLYCERATE KINASE | GENE-TRANSCRIPTION | CELL BIOLOGY | Mitochondria - enzymology | Receptor, Epidermal Growth Factor - genetics | Glioblastoma - enzymology | Cell Proliferation | Prognosis | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Pyruvate Dehydrogenase Complex - genetics | Cell Hypoxia | Receptor, Epidermal Growth Factor - metabolism | Transfection | Glioblastoma - genetics | RNA Interference | Time Factors | Female | Peptidylprolyl Isomerase - metabolism | Peptidylprolyl Isomerase - genetics | Phosphoglycerate Kinase - genetics | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Pyruvate Dehydrogenase Complex - metabolism | Signal Transduction | Protein-Serine-Threonine Kinases - genetics | Rats | NIMA-Interacting Peptidylprolyl Isomerase | Mitochondria - pathology | Citric Acid Cycle | Protein Transport | Animals | Mice, Nude | Proto-Oncogene Proteins B-raf - genetics | Glioblastoma - pathology | Cell Line, Tumor | Protein Binding | Enzyme Activation | Mutation | Phosphoglycerate Kinase - metabolism | Lactates | Glucose metabolism | Gliomas | Isomerization | Mitochondrial DNA | Protein kinases | Cells | Medical colleges | Brain tumors
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2018, Volume 72, Issue 4, pp. 650 - 660.e8
DNA replication is initiated by assembly of the kinase cell division cycle 7 (CDC7) with its regulatory activation subunit, activator of S-phase kinase (ASK),... 
ERK1/2 | DNA replication | PGK1 | CK2α | ASK | CDC7 | tumorigenesis | ADP | phosphorylation | EGFR | KAPPA-B ACTIVATION | NUCLEOTIDE SYNTHESIS | COMPLEX | HISTONE H3 | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | AUTOPHAGY | TUMORIGENESIS | GENE-TRANSCRIPTION | LYSOSOMAL BIOGENESIS | CELL BIOLOGY | Casein | Brain tumors | DNA
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 33, pp. 55073 - 55083
Glioma is a primary malignancy in central nervous system. Radiotherapy has been used as one of the standard treatments for glioma for decades. Since... 
PGK1 | Prognosis | Radiosensibility | Glioma | CFL1 | SURVIVAL | MOLECULAR-BIOLOGY | radiosensibility | DOWN-REGULATION | prognosis | CANCER | CELL BIOLOGY | MALIGNANT GLIOMA | OVEREXPRESSION | glioma | RADIOTHERAPY | RADIOSENSITIVITY | EXPRESSION | PROGRESSION
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 07/2018, Volume 66, Issue 28, pp. 7417 - 7427
Journal Article
by Cui, J and Zhou, Y and Hu, H and Zhao, L and Du, Z and Du, H
Clinical & Experimental Immunology, ISSN 0009-9104, 12/2018, Volume 194, Issue 3, pp. 371 - 379
Journal Article