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The EMBO Journal, ISSN 0261-4189, 06/2018, Volume 37, Issue 12, pp. e98694 - n/a
Mutations in the leucine‐rich repeat kinase 2 (LRRK2) are associated with Parkinson's disease, chronic inflammation and mycobacterial infections. Although... 
phagosome | Parkinson's disease | Rubicon | LRRK2 | tuberculosis | PROTEOME | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | ALPHA-SYNUCLEIN | DISTINCT ROLES | CELL BIOLOGY | SELECTIVE INHIBITOR | POTENT | MUTATIONS | ASSOCIATION | CELL | PARKINSONS-DISEASE | Phagosomes - microbiology | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - immunology | Humans | Mycobacterium tuberculosis - immunology | Intracellular Signaling Peptides and Proteins - immunology | Phosphatidylinositol 3-Kinases - immunology | Mice, Knockout | Phosphatidylinositol 3-Kinases - genetics | Tuberculosis - immunology | Phagosomes - immunology | Animals | Tuberculosis - genetics | Mice | Intracellular Signaling Peptides and Proteins - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - genetics | Macrophages - immunology | Macrophages - microbiology | Phagosomes - genetics | Phagolysosomes | Parkinsons disease | Phagosomes | Innate immunity | Infections | Leucine | Kinases | Macrophages | Autophagy | Immunity | Recruitment | Inhibition | LRRK2 protein | Movement disorders | Immune response | Neurodegenerative diseases | Maturation | Pharmacology | Inflammation | Molecular chains | 1-Phosphatidylinositol 3-kinase | Tuberculosis | Proteomics | Replication | Mutation | Phagocytosis | Index Medicus | Microbiology, Virology & Host Pathogen Interaction | Membrane & Intracellular Transport | Immunologi | Immunology | Pathobiology | Microbiology in the medical area | Biokemi och molekylärbiologi | Cell and Molecular Biology | Biochemistry and Molecular Biology | Mikrobiologi inom det medicinska området | Cell- och molekylärbiologi | Patobiologi
Journal Article
Science, ISSN 0036-8075, 6/2004, Volume 304, Issue 5678, pp. 1800 - 1804
Pathogenic mycobacteria resist lysosomal delivery after uptake into macrophages, allowing them to survive intracellularly. We found that the eukaryotic-like... 
Bacteriophages | Mycobacterium | Phagosomes | Lysosomes | Antibodies | Bacteria | Electrophoresis | Reports | Infections | Macrophages | Organelles | TUBERCULOSIS PHAGOSOME | PHAGOSOME MATURATION | ARREST | FUSION | BIOGENESIS | MULTIDISCIPLINARY SCIENCES | SEQUENCE | EARLY ENDOSOMES | MICE | INHIBITORS | INTRACELLULAR SURVIVAL | Phagosomes - microbiology | Phagosomes - enzymology | Phagosomes - physiology | Cyclic GMP-Dependent Protein Kinases - metabolism | Lysosomes - physiology | Mycobacterium smegmatis - pathogenicity | Mycobacterium tuberculosis - drug effects | Cyclic GMP-Dependent Protein Kinases - genetics | Mycobacterium tuberculosis - pathogenicity | Mycobacterium bovis - drug effects | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Mycobacterium bovis - enzymology | Gene Deletion | Mycobacterium bovis - pathogenicity | Mycobacterium smegmatis - enzymology | Macrophages - microbiology | Amides - pharmacology | Cell Line | Macrophages - ultrastructure | Vacuoles - microbiology | Mycobacterium smegmatis - genetics | Signal Transduction | Enzyme Inhibitors - pharmacology | Thiophenes - pharmacology | Animals | Lysosomes - microbiology | Mycobacterium tuberculosis - enzymology | Macrophages - drug effects | Mice | Mycobacterium bovis - growth & development | Mycobacterium smegmatis - physiology | Mycobacterium tuberculosis - growth & development | Physiological aspects | Tuberculosis | Bacterial infections | Research | Mycobacteria | Pathogens | Molecules | Microbiology | Bacterial proteins | Index Medicus
Journal Article
Annals of Neurology, ISSN 0364-5134, 2009, Volume 66, Issue 3, pp. 378 - 389
Journal Article
Nature Immunology, ISSN 1529-2908, 06/2013, Volume 14, Issue 6, pp. 543 - 553
Phagocytosis is a fundamental cellular process that is pivotal for immunity as it coordinates microbial killing, innate immune activation and antigen... 
PROTEOLYTIC CLEAVAGE | H+-ATPASE ACTIVITY | DENDRITIC CELLS | TOLL-LIKE RECEPTOR | BACTERIAL LIGANDS | ACIDIFICATION | INNATE IMMUNE-SYSTEM | STAPHYLOCOCCUS-AUREUS | IMMUNOLOGY | MATURATION | NALP3 INFLAMMASOME | Phagosomes - microbiology | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Staphylococcus aureus - physiology | Humans | NADPH Oxidases - metabolism | NADPH Oxidases - immunology | Caspase 1 - metabolism | Immunoblotting | Caspase 1 - immunology | Mice, 129 Strain | Enzyme Activation - immunology | Host-Pathogen Interactions - immunology | Phagosomes - immunology | Flow Cytometry | Reactive Oxygen Species - immunology | HEK293 Cells | Phagosomes - ultrastructure | Membrane Glycoproteins - immunology | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Mice, Inbred C57BL | Phagosomes - metabolism | Cells, Cultured | Phagocytosis - immunology | Mice, Transgenic | Microscopy, Electron | NADPH Oxidase 2 | Mice, Knockout | Microscopy, Confocal | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | Staphylococcus aureus - immunology | Mice | Hydrogen-Ion Concentration | Oxidases | Physiological aspects | Phagosomes | Bacteria | Genetic aspects | Research | Health aspects | Index Medicus
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 08/2012, Volume 37, Issue 2, pp. 223 - 234
Autophagy is a fundamental biological process of the eukaryotic cell contributing to diverse cellular and physiological functions including cell-autonomous... 
IMMUNITY | MYCOBACTERIUM-TUBERCULOSIS INFECTION | MUTANT HUNTINGTIN | P62/SQSTM1 | ADAPTER | INNATE | KAPPA-B | IMMUNOLOGY | PROTEINS | HUNTINGTONS-DISEASE | CELL | Green Fluorescent Proteins | Phosphorylation | Mycobacterium bovis - immunology | Microtubule-Associated Proteins - genetics | Sequestosome-1 Protein | Humans | rab GTP-Binding Proteins - genetics | Serine - immunology | Autophagy - immunology | Phagosomes - immunology | Interleukin-1beta - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - immunology | Macrophages - immunology | Protein-Serine-Threonine Kinases - metabolism | Phagosomes - drug effects | Heat-Shock Proteins - metabolism | Phagosomes - metabolism | Interleukin-1beta - immunology | Microtubule-Associated Proteins - antagonists & inhibitors | Serine - metabolism | Heat-Shock Proteins - immunology | Tuberculosis - immunology | Microscopy, Confocal | Autophagy-Related Protein 7 | Macrophages - metabolism | Animals | rab GTP-Binding Proteins - immunology | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Mice | RNA, Small Interfering | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Research | Universities and colleges | Macrophages | Oncology, Experimental | Cancer | Proteins | Antimicrobial agents | Microscopy | Kinases | Autophagy | Rodents | Index Medicus | Pathogens | BCG | Interleukin 1 | Phagosomes | Inflammation | Immunity | Organelles | Phagocytosis | membrane trafficking
Journal Article
Circulation, ISSN 0009-7322, 06/2012, Volume 125, Issue 25, pp. 3170 - 3181
Journal Article
Plos Pathogens, ISSN 1553-7366, 2012, Volume 8, Issue 2, pp. e1002507 - e1002507
Survival within macrophages is a central feature of Mycobacterium tuberculosis pathogenesis. Despite significant advances in identifying new immunological... 
SYSTEM | ESCHERICHIA-COLI | MICROBIOLOGY | ENHANCED PROTECTION | VIRULENCE | ESAT-6 SECRETION | VIROLOGY | BETA-LACTAMASE | BOVIS BCG | ALVEOLAR MACROPHAGES | VII SECRETION | PARASITOLOGY | REAL-TIME | Phagosomes - microbiology | Cell Line | Salmonella typhimurium - pathogenicity | Homeodomain Proteins - metabolism | Humans | Phagosomes - metabolism | Shigella flexneri - pathogenicity | Mycobacterium tuberculosis - immunology | Mycobacterium Infections - metabolism | Mycobacterium marinum - pathogenicity | Phagosomes - pathology | Mycobacterium Infections - immunology | Mycobacterium tuberculosis - pathogenicity | Macrophages - metabolism | Immune Evasion | Mycobacterium marinum - immunology | Cell Death | Fluorescence Resonance Energy Transfer - methods | Mycobacterium Infections - pathology | Mycobacterium marinum - metabolism | Mycobacterium tuberculosis - metabolism | Macrophages - microbiology | Mycobacterium tuberculosis | Cell death | Phagosomes | Physiological aspects | Development and progression | Research | Health aspects | Proteins | Signal transduction | Tuberculosis | Algorithms | Toxicity | Software | Infections | Experiments | Apoptosis | Index Medicus | Mycobacterium marinum | Biochemistry, Molecular Biology | Shigella flexneri | Mycobacterium Infections | Macrophages | Cellular Biology | Salmonella typhimurium | Life Sciences | Homeodomain Proteins | Fluorescence Resonance Energy Transfer | Biomolecules | Cell Behavior
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