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ophthalmology (92) 92
index medicus (83) 83
pharmacological vitreolysis (78) 78
posterior vitreous detachment (72) 72
humans (59) 59
pharmacologic vitreolysis (46) 46
vitrectomy (44) 44
male (35) 35
ocriplasmin (35) 35
microplasmin (32) 32
animals (31) 31
female (31) 31
vitreomacular traction (31) 31
vitreous body - drug effects (29) 29
vitreous (27) 27
optical coherence tomography (26) 26
aged (25) 25
adhesion (24) 24
vitreous body - pathology (24) 24
intravitreal injections (21) 21
macular degeneration (21) 21
macular hole (21) 21
middle aged (19) 19
tomography, optical coherence (19) 19
internal limiting membrane (18) 18
vitreoretinal interface (18) 18
eye diseases (17) 17
hyaluronidase (17) 17
diabetic macular edema (16) 16
diabetic retinopathy (16) 16
fibrinolysin - therapeutic use (16) 16
rabbit (16) 16
vitreomacular adhesion (16) 16
genetic structures (15) 15
rabbits (15) 15
retrospective studies (15) 15
vitreous detachment - chemically induced (15) 15
intravitreal injection (14) 14
plasmin (14) 14
sense organs (14) 14
vitreous body - metabolism (14) 14
fibrinolysin - administration & dosage (13) 13
microscopy, electron, scanning (13) 13
peptide fragments - therapeutic use (13) 13
visual acuity (13) 13
enzymes (12) 12
fibrinolysin - pharmacology (12) 12
medicine & public health (12) 12
surgery (12) 12
detachment (11) 11
prospective studies (11) 11
retina (11) 11
traction (11) 11
vitrectomy - methods (11) 11
enzyme-assisted vitrectomy (10) 10
fibrinolytic agents - therapeutic use (10) 10
fibronectin (10) 10
injection (10) 10
injections (10) 10
swine (10) 10
assisted vitrectomy (9) 9
choroidal neovascularization (9) 9
collagen (9) 9
diabetic-retinopathy (9) 9
macular holes (9) 9
retina - drug effects (9) 9
retinal diseases - diagnosis (9) 9
retinopathy (9) 9
studies (9) 9
vitreolysis (9) 9
vitreous body - ultrastructure (9) 9
abridged index medicus (8) 8
aged, 80 and over (8) 8
autologous plasmin (8) 8
diabetes (8) 8
edema (8) 8
enzyme (8) 8
eye (8) 8
eye diseases - diagnosis (8) 8
fibrinolysin - adverse effects (8) 8
macular edema (8) 8
peptide fragments - administration & dosage (8) 8
pharmacology & pharmacy (8) 8
plasmin-assisted vitrectomy (8) 8
retina - pathology (8) 8
retinal perforations - diagnosis (8) 8
retinal perforations - drug therapy (8) 8
retinal vein occlusion (8) 8
tomography (8) 8
treatment outcome (8) 8
vitreous detachment - diagnosis (8) 8
vitreous detachment - drug therapy (8) 8
vitreous detachment - etiology (8) 8
electroretinography (7) 7
fluorescein angiography (7) 7
follow-up studies (7) 7
laminin (7) 7
pars-plana vitrectomy (7) 7
peptide fragments - adverse effects (7) 7
retina - ultrastructure (7) 7
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Journal Article
Journal Article
Journal of Ophthalmic and Vision Research, ISSN 2008-2010, 2010, Volume 5, Issue 1, pp. 44 - 52
The vitreoretinal interface is involved in a wide range of vitreoretinal disorders and separation of the posterior vitreous face from the retinal surface is an... 
Enzymatic vitreolysis | Pharmacologic vitreolysis | Pharmacologic Vitreolysis | Enzymatic Vitreolysis | Review | Pharmacologic Vitreolysis; Enzymatic Vitreolysis
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 11/2015, Volume 9, pp. 6259 - 6268
Journal Article
Retinal Cases and Brief Reports, ISSN 1935-1089, 12/2013, Volume 7, Issue 1, pp. 57 - 61
To prospectively characterize macular structure and function as assessed by combined three-dimensional spectral-domain optical coherence tomography and... 
Macular hole | Vitreous | Combined OCT/SLO imaging | Pharmacologic vitreolysis | Central vision | Contrast-sensitive threshold Amsler grid
Journal Article
Ophthalmology, ISSN 0161-6420, 2015, Volume 122, Issue 1, pp. 117 - 122
Purpose To evaluate the efficacy of a single intravitreal injection of ocriplasmin 125 μg across relevant subpopulations of patients with symptomatic... 
Ophthalmology | TRACTION | TRIAL | VITRECTOMY | PHARMACOLOGICAL VITREOLYSIS | POSTERIOR VITREOUS DETACHMENT | MICROPLASMIN | OPHTHALMOLOGY | Consulting services | Analysis
Journal Article
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, ISSN 0023-2165, 06/2019, Volume 236, Issue 6, pp. 791 - 797
Pharmacological vitreolysis with ocriplasmin is an effective treatment option for eyes with vitreomacular traction. Pre-marketing and post-marketing clinical... 
SYMPTOMATIC VITREOMACULAR ADHESION | LAMININ | INTERNAL LIMITING MEMBRANE | ocriplasmin | TRACTION | INTRAVITREAL OCRIPLASMIN | VITRECTOMY | vitreomacular traction | pharmacologic vitreolysis | POSTERIOR VITREOUS DETACHMENT | OUTER RETINA | OPHTHALMOLOGY | macular hole | side effects | VITREOLYSIS | OUTCOMES
Journal Article
AMERICAN JOURNAL OF OPHTHALMOLOGY, ISSN 0002-9394, 01/2010, Volume 149, Issue 1, pp. 172 - 173
Journal Article
Retina, ISSN 0275-004X, 01/2017, Volume 37, Issue 12, pp. 2295 - 2303
Journal Article
Journal Article