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Journal Article
Leukemia, ISSN 0887-6924, 05/2015, Volume 29, Issue 5, pp. 1123 - 1132
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2006, Volume 354, Issue 24, pp. 2542 - 2551
Journal Article
Leukemia, ISSN 0887-6924, 07/2011, Volume 25, Issue 7, pp. 1159 - 1167
The cytotoxic farnesyl transferase inhibitor BMS-214662 has been shown to potently induce mitochondrial apoptosis in primitive CD34+ chronic myeloid leukaemia... 
BMS-214662 | HSC | MEK inhibitor | CML | TKI | PD184352 | CHRONIC MYELOGENOUS LEUKEMIA | ACTIVATION | KINASE | INDUCE APOPTOSIS | CHRONIC MYELOID-LEUKEMIA | ONCOLOGY | IMATINIB | RESISTANCE | QUIESCENT | DIFFERENTIATION | HEMATOLOGY | Antigens, CD34 - analysis | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myeloid, Chronic-Phase - pathology | Neoplasm Proteins - antagonists & inhibitors | K562 Cells - drug effects | Blast Crisis - enzymology | MAP Kinase Kinase 1 - genetics | Tumor Cells, Cultured - enzymology | Genes, Dominant | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Benzamides - pharmacology | Farnesyltranstransferase - antagonists & inhibitors | MAP Kinase Kinase Kinases - antagonists & inhibitors | Hematopoietic Stem Cells - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology | Benzodiazepines - pharmacology | Blast Crisis - pathology | Tumor Cells, Cultured - drug effects | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Leukemia, Myeloid, Chronic-Phase - enzymology | K562 Cells - enzymology | Drug Synergism | Recombinant Fusion Proteins - genetics | Genes, ras | Hematopoietic Stem Cells - enzymology | Neoplastic Stem Cells - enzymology | Drug Screening Assays, Antitumor | Oncogene Protein p21(ras) - genetics | Antimitotic agents | Physiological aspects | Chronic myeloid leukemia | Research | Drug therapy | Antineoplastic agents | Protein kinases | Health aspects | Apoptosis | FTI | CD34
Journal Article
European Journal of Haematology, ISSN 0902-4441, 01/2017, Volume 98, Issue 1, pp. 57 - 66
Journal Article
Blood, ISSN 0006-4971, 12/2011, Volume 118, Issue 26, pp. 6760 - 6768
Journal Article
Blood, ISSN 0006-4971, 2011, Volume 118, Issue 3, pp. 686 - 692
Journal Article