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The Lancet (British edition), ISSN 0140-6736, 2016, Volume 387, Issue 10038, pp. 2630 - 2640
.... The efficacy and safety of tocilizumab, an interleukin 6 receptor-α inhibitor, was assessed in the faSScinate phase 2 trial in patients with systemic sclerosis... 
Internal Medicine | Medicine(all) | Multicenter Study | Clinical Trial, Phase II | Randomized Controlled Trial | Research Support, Non-U.S. Gov't | Journal Article | INTERSTITIAL LUNG-DISEASE | MORTALITY | SURVIVAL | MEDICINE, GENERAL & INTERNAL | PLACEBO | LYSOPHOSPHATIDIC ACID | DIFFUSE SCLERODERMA | SKIN FIBROSIS | INTERLEUKIN-6 | EXPRESSION | SSC SKIN | Biomarkers - metabolism | Antibodies, Monoclonal, Humanized - therapeutic use | Double-Blind Method | Europe | Humans | Middle Aged | Scleroderma, Systemic - metabolism | Male | Treatment Outcome | United Kingdom | Canada | Vital Capacity | Antibodies, Monoclonal, Humanized - administration & dosage | Injections, Subcutaneous | Scleroderma, Systemic - complications | Interleukin-6 - physiology | Adult | Female | Aged | Scleroderma, Systemic - drug therapy | Medical colleges | Adults | Systemic scleroderma | Interleukins | Scleroderma (Disease) | Analysis | Tissue | Cytokines | Ulcers | Biomarkers | Fibroblasts | Clinical trials | Patient safety | Skin diseases | Skin | Health risk assessment | Scleroderma | Drug therapy | Pathogenesis | Interleukin | Evidence-based medicine | Itching | Interleukin 6 | Cost-benefit analysis | Safety | Thickening | Effectiveness | Mortality | Lung diseases | Medical treatment | Rheumatology | Patients | Studies | Systemic sclerosis | Least squares | Autoimmune diseases
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 05/2011, Volume 10, Issue 5, pp. 328 - 329
...Well-conducted Phase II clinical trials provide the data required to determine whether there is a case to be made, both scientifically and commercially... 
Clinical Trials, Phase II as Topic - statistics & numerical data | Drug Industry - statistics & numerical data | Pharmaceutical Preparations - administration & dosage | Humans | Treatment Failure | Drug Design
Journal Article
Lung Cancer, ISSN 0169-5002, 2016, Volume 99, pp. 41 - 45
Journal Article
Cancer, ISSN 0008-543X, 01/2015, Volume 121, Issue 2, pp. 234 - 242
Journal Article
OncoImmunology, ISSN 2162-4011, 03/2014, Volume 3, Issue 3, p. e27878
Accumulating evidence suggests that the clinical efficacy of selected anticancer drugs, including conventional chemotherapeutics as well as targeted anticancer... 
calreticulin | autophagy | dendritic cells | HMGB1 | ATP | epothilone B | Epothilone B | Calreticulin | Dendritic cells | Autophagy | MULTICENTER PHASE-II | IMMUNOLOGY | ANTITUMOR-ACTIVITY | CALRETICULIN EXPOSURE | NEOADJUVANT CHEMOTHERAPY | ONCOLOGY | BIOMARKERS HMGB1 | BREAST-CANCER PATIENTS | WEEKLY OXALIPLATIN | 1ST-LINE THERAPY | TUMOR MICROENVIRONMENT | MOLECULAR-MECHANISMS
Journal Article