X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (59) 59
phd2 (57) 57
humans (44) 44
hypoxia (32) 32
animals (27) 27
hypoxia-inducible factor 1, alpha subunit - metabolism (22) 22
mice (22) 22
cancer (20) 20
hif (19) 19
biochemistry & molecular biology (16) 16
cell biology (16) 16
erythrocytosis (16) 16
hematology (16) 16
hif-1-alpha (16) 16
hypoxia-inducible factor (16) 16
expression (15) 15
hydroxylase domain protein-2 (15) 15
hypoxia-inducible factor-proline dioxygenases (15) 15
mutation (15) 15
phd2 mutation (15) 15
proteins (15) 15
angiogenesis (14) 14
female (14) 14
hypoxia-inducible factor-proline dioxygenases - metabolism (14) 14
male (14) 14
erythropoietin (13) 13
hypoxia-inducible factor 1, alpha subunit - genetics (13) 13
hypoxia-inducible-factor (13) 13
polycythemia - genetics (13) 13
prolyl hydroxylase (12) 12
analysis (11) 11
article (11) 11
hydroxylation (11) 11
polycythemia (11) 11
genetic aspects (10) 10
hif-alpha (10) 10
hypoxia-inducible factor-proline dioxygenases - genetics (10) 10
procollagen-proline dioxygenase - genetics (10) 10
procollagen-proline dioxygenase - metabolism (10) 10
family (9) 9
mice, knockout (9) 9
oxygen - metabolism (9) 9
signal transduction (9) 9
vhl (9) 9
cells (8) 8
congenital polycythemia (8) 8
gene expression (8) 8
genes (8) 8
hydroxylases (8) 8
hypoxia - metabolism (8) 8
medicine, research & experimental (8) 8
metabolism (8) 8
metastasis (8) 8
oncology (8) 8
pathway (8) 8
prolyl hydroxylation (8) 8
research (8) 8
abridged index medicus (7) 7
egln1 (7) 7
gene (7) 7
hif-1α (7) 7
hydroxylase (7) 7
hypoxia inducible factor (7) 7
mice, inbred c57bl (7) 7
middle aged (7) 7
overexpression (7) 7
tumors (7) 7
adult (6) 6
basic helix-loop-helix transcription factors - genetics (6) 6
cell hypoxia (6) 6
cells, cultured (6) 6
factor-1-alpha (6) 6
genetics & heredity (6) 6
hif-1 (6) 6
hif-1 alpha (6) 6
oxygen (6) 6
oxygen homeostasis (6) 6
pathology (6) 6
polycythemia - metabolism (6) 6
prolyl hydroxylases (6) 6
amino acid sequence (5) 5
apoptosis (5) 5
biology (5) 5
cell line, tumor (5) 5
enzymes (5) 5
erythropoietin - genetics (5) 5
factor-i (5) 5
gene expression regulation (5) 5
genetic research (5) 5
hypoxia-inducible factor 1 - metabolism (5) 5
hypoxia-inducible factors (5) 5
medicine (5) 5
neovascularization, pathologic - metabolism (5) 5
pharmacology & pharmacy (5) 5
physiological aspects (5) 5
procollagen-proline dioxygenase - physiology (5) 5
proline hydroxylation (5) 5
protein binding (5) 5
research paper (5) 5
activation (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Clinical Case Reports, ISSN 2050-0904, 06/2018, Volume 6, Issue 6, pp. 1109 - 1111
Key Clinical Message Congenital erythrocytosis is a hereditary disorder due to an increase in red cell mass that can be caused by mutations in proteins... 
hypoxia | phd2 | thrombosis | Congenital erythrocytosis | Mutation
Journal Article
Blood Reviews, ISSN 0268-960X, 09/2019, Volume 37, p. 100590
Journal Article
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, ISSN 0390-6078, 07/2008, Volume 93, Issue 7, pp. 1068 - 1071
HIF2A transcription factor plays a central role in the regulation of the hypoxia responding pathway in mammalian cells, by modulating erythropoiesis and... 
HYDROXYLASE DOMAIN PROTEIN-2 | MYELOPROLIFERATIVE DISEASES | ERYTHROPOIETIN | HOMEOSTASIS | PHD2 | GENE | familial erythrocytosis | CHILDHOOD POLYCYTHEMIA-VERA | HIF2A | ESSENTIAL THROMBOCYTHEMIA | HEMATOLOGY
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2009, Volume 284, Issue 14, pp. 9050 - 9058
A classic physiologic response to hypoxia in humans is the up-regulation of the ERYTHROPOIETIN (EPO) gene, which is the central regulator of red blood cell... 
PHD2 | DOMAIN PROTEIN-2 | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | HIF2A GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROXYLATION | TUMOR-SUPPRESSOR GENE | FAMILIAL ERYTHROCYTOSIS | HIF-1-ALPHA | CONGENITAL POLYCYTHEMIA | OXYGEN HOMEOSTASIS | Mechanisms of Signal Transduction
Journal Article
Blood Cells, Molecules and Diseases, ISSN 1079-9796, 2008, Volume 40, Issue 2, pp. 160 - 165
The hypoxia-inducible factor HIF-1 is the key regulator in cellular adaptation to hypoxia. Acting through a complex pathway, interconnected with VHL and... 
Oxygen sensor | HIF-1α | PHD2 | Erythrocytosis | Polycythemia | polycythemia | POLYCYTHEMIA-VERA | HIF-1 alpha | MYELOPROLIFERATIVE DISORDERS | HIF | FAMILY | FACTOR 1-ALPHA HIF-1-ALPHA | erythrocytosis | DESTRUCTION | O-2 | TYROSINE KINASE JAK2 | oxygen sensor | HEMATOLOGY | HYPOXIA-INDUCIBLE FACTOR-1
Journal Article
Haematologica, ISSN 0390-6078, 01/2012, Volume 97, Issue 1, pp. 9 - 14
Journal Article
Best Practice & Research: Clinical Haematology, ISSN 1521-6926, 2014, Volume 27, Issue 2, pp. 95 - 106
Hereditary erythrocytosis, thrombocytosis, and neutrophilia are rare inherited syndromes which exhibit Mendelian inheritance. Some patients with primary... 
Hematology, Oncology and Palliative Medicine | thrombocytosis | familial | TPO | neutrophilia | hereditary erythrocytosis | MPL | polycythaemia | JAK2 | Familial | Neutrophilia | Thrombocytosis | Polycythaemia | Hereditary erythrocytosis | FAMILIAL ESSENTIAL THROMBOCYTHEMIA | VON-HIPPEL-LINDAU | MPL BALTIMORE | GERMLINE JAK2 MUTATION | SPLICE DONOR MUTATION | PHD2 MUTATION | HYDROXYLASE DOMAIN PROTEIN-2 | ACTIVATING MUTATION | BISPHOSPHOGLYCERATE MUTASE | CONGENITAL POLYCYTHEMIA | HEMATOLOGY | Polycythemia - diagnosis | Polycythemia - genetics | Gelsolin - metabolism | Humans | Leukocyte Disorders - metabolism | Oxygen - metabolism | Receptors, Erythropoietin - genetics | Receptors, Colony-Stimulating Factor - genetics | Receptors, Colony-Stimulating Factor - metabolism | Janus Kinase 2 - metabolism | Thrombocytosis - metabolism | Polycythemia - pathology | Erythropoietin - metabolism | Thrombocytosis - pathology | Bisphosphoglycerate Mutase - metabolism | Gene Expression | Thrombopoietin - metabolism | Signal Transduction | Janus Kinase 2 - genetics | Hemoglobins - metabolism | Leukocyte Disorders - pathology | Polycythemia - congenital | Receptors, Thrombopoietin - metabolism | Thrombocytosis - diagnosis | Erythropoietin - genetics | Receptors, Thrombopoietin - genetics | Thrombopoietin - genetics | Leukocyte Disorders - diagnosis | Leukocyte Disorders - congenital | Polycythemia - metabolism | Gelsolin - genetics | Leukocyte Disorders - genetics | Mutation | Receptors, Erythropoietin - metabolism | Bisphosphoglycerate Mutase - genetics | Thrombocytosis - genetics | Glycoproteins | Gene mutations | Polycythemia
Journal Article
Blood, ISSN 0006-4971, 05/2011, Volume 117, Issue 20, pp. 5485 - 5493
Prolyl-4-hydroxylation is necessary for proper structural assembly of collagens and oxygen-dependent protein stability of hypoxia-inducible transcription... 
CANCER-CELLS | HYDROXYLASE DOMAIN PROTEIN-2 | OXIDATIVE STRESS | HYPOXIA-INDUCIBLE-FACTOR | PROLYL-HYDROXYLASES | FACTOR INHIBITING HIF | MICE | HEMATOLOGY | ASCORBIC-ACID | ERYTHROCYTOSIS | PHD2 MUTATION | Red Cells, Iron, and Erythropoiesis
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2017, Volume 127, Issue 9, pp. 3407 - 3420
Journal Article