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Cell Metabolism, ISSN 1550-4131, 2018, Volume 28, Issue 6, pp. 935 - 945.e5
Reprogramming of somatic cells to induced pluripotent stem cells reconfigures chromatin modifications. Whether and how this process is regulated by signals... 
reprogramming | histone lysine methylation | induced pluripotent stem cells | mitochondrial permeability transition pore | PHF8
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2018, Volume 496, Issue 3, pp. 981 - 987
Adult acute lymphoblastic leukemia (ALL) is a malignant disorder of lymphoid progenitor cells that is associated with a high risk of relapse and poor... 
MEK1 | MEK/ERK pathway | Acute lymphoblastic leukemia | PD184352 | PHF8 | MEKI | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | PROGRESSION
Journal Article
FEBS Letters, ISSN 0014-5793, 03/2019, Volume 593, Issue 5, pp. 487 - 498
Histone3‐lysine9 (H3K9) residues not only control gene expression, but also contribute to RNA splicing. Here, the H3K9 histone demethylase PHF8 was... 
endothelium | HLA‐G | splicing | epigenetics | PHF8 | MENTAL-RETARDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | HLA-G | JUMONJI DOMAIN | SNRNP | CELL BIOLOGY | BIOPHYSICS | GENE | INTEGRATION | MUTATION | BINDING
Journal Article
Nature Communications, ISSN 2041-1723, 05/2017, Volume 8, Issue 1, p. 15142
PHF8 is a histone demethylase with specificity for repressive modifications. While mutations of PHF8 have been associated with cognitive defects and cleft... 
DEMETHYLASE PHF8 | LINKED MENTAL-RETARDATION | GENE | CHROMATIN | SOCIAL DEFEAT | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | TRANSCRIPTION | ELEVATED PLUS-MAZE | BRAIN | TEST-RETEST PARADIGM
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2015, Volume 290, Issue 7, pp. 4075 - 4085
Cyclin E-CDK2 is a key regulator in G1/S transition. Previously, we identified a number of CDK2-interacting proteins, including PHF8 (plant homeodomain finger... 
TRANSITION | RECRUITMENT | HISTONE DEMETHYLASE PHF8 | LINKED MENTAL-RETARDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RIBOSOMAL-RNA SYNTHESIS | S-PHASE PROGRESSION | DEPENDENT KINASE 2 | E/CDK2 SUBSTRATE | BINDING | GENE-TRANSCRIPTION | Oncogene Proteins - genetics | RNA, Small Interfering - genetics | Phosphorylation | Cell Proliferation | Histone Demethylases - antagonists & inhibitors | Immunoprecipitation | Humans | Cyclin E - genetics | Histone Demethylases - genetics | DNA Methylation | Flow Cytometry | Chromatin Immunoprecipitation | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Real-Time Polymerase Chain Reaction | DNA, Ribosomal - genetics | Cyclin-Dependent Kinase 2 - metabolism | Enzyme-Linked Immunosorbent Assay | RNA, Messenger - genetics | Cells, Cultured | Gene Expression Regulation | Oncogene Proteins - metabolism | Cyclin-Dependent Kinase 2 - genetics | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Transcription Factors - metabolism | Histone Demethylases - metabolism | S Phase - physiology | Cyclin E - metabolism | HeLa Cells | Histones - metabolism | Cell Cycle | Cell Signaling | Cyclin | Cyclin E-CDK2, PHF8, Phosphorylation, rRNA Transcription | Cell Biology | Cyclin-dependent Kinase (CDK)
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2012, Volume 48, Issue 3, pp. 445 - 458
Journal Article