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BBA - Biomembranes, ISSN 0005-2736, 05/2018, Volume 1860, Issue 5, pp. 1046 - 1056
The PKC isozymes represent the most prominent family of signaling proteins mediating response to the ubiquitous second messenger diacylglycerol. Among them,... 
PMA | PKCθ | Phorbol ester | Diacylglycerol | Binding affinity | Membrane translocation | C1a domain | PKCO | ACTIVATION | MECHANISM | CRYSTAL-STRUCTURE | DELTA | BIOCHEMISTRY & MOLECULAR BIOLOGY | Cla domain | IDENTIFICATION | BIOPHYSICS | AFFINITY | REGULATORY DOMAIN | GASTROINTESTINAL STROMAL TUMORS | CELL | PKC-THETA | Phorbol esters | T cells | Isoenzymes | Protein kinases | Index Medicus
Journal Article
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 09/2005, Volume 16, Issue 9, pp. 4375 - 4385
Protein kinase D2 (PKD2) belongs to the PKD family of serine/threonine kinases that is activated by phorbol esters and G protein-coupled receptors (GPCRs). Its... 
Index Medicus
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 01/2019, Volume 368, Issue 1, pp. 59 - 65
In the 1980s, researchers used binding studies to show that there is a melatonin binding site in addition to the receptors described previously. It was first... 
5-METHOXYCARBONYLAMINO-N-ACETYLTRYPTAMINE | BIOCHEMISTRY | KINASE | OXIDOREDUCTASE-2 | PHARMACOLOGY & PHARMACY | INTRAOCULAR-PRESSURE | RECEPTOR AGONIST | EXPRESSION | PHORBOL ESTER BINDING | DRUG-METABOLISM | PHARMACOLOGICAL-PROPERTIES
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/1989, Volume 86, Issue 13, pp. 4868 - 4871
Journal Article
Journal Article
HUMAN MOLECULAR GENETICS, ISSN 0964-6906, 01/2015, Volume 24, Issue 2, pp. 525 - 539
Amyloid assemblies are associated with a wide range of human disorders, including Alzheimer's and Parkinson's diseases. Here, we identify protein kinase C... 
PURKINJE-CELLS | NUCLEAR IMPORT | SYNAPSE ELIMINATION | CEREBELLAR-ATAXIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | GENETICS & HEREDITY | SPINOCEREBELLAR ATAXIA TYPE-14 | HUNTINGTIN | AGGREGATION | PHORBOL ESTER BINDING | C-GAMMA
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2003, Volume 278, Issue 46, pp. 46179 - 46187
Cerebral amyloid angiopathy (CAA) due to beta-amyloid (Abeta) is one of the specific pathological features of familial Alzheimer's disease. Abeta mainly... 
APP | DUTCH-TYPE | FIBRILS | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTATION | STATE | PRECURSOR PROTEIN | PHORBOL ESTER-BINDING | AGGREGATION | SENILE PLAQUES | cerebral amyloid angiopathy
Journal Article
NEUROTOXICOLOGY, ISSN 0161-813X, 03/2003, Volume 24, Issue 2, pp. 187 - 198
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 07/2008, Volume 283, Issue 28, pp. 19854 - 19863
Spinocerebellar ataxia type 14 (SCA14) is an autosomal dominant neurodegenerative disease caused by mutations in protein kinase C gamma(PKC gamma).... 
SYNAPSE ELIMINATION | CEREBELLAR-ATAXIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ATAXIA TYPE-14 | TRPC3 CHANNELS | CLIMBING FIBER INNERVATION | IMPAIRED MOTOR COORDINATION | PLASMA-MEMBRANE | PHORBOL ESTER BINDING | LIVING CELLS | PKC-GAMMA
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 2006, Volume 1761, Issue 8, pp. 838 - 849
C2 domains are a ubiquitous structural module and many of them function in Ca -dependent membrane binding and thereby serve as Ca effectors for divergent Ca... 
Signaling | Calcium | Subcellular localization | Membrane | Membrane trafficking | C2 domain | Lipid | PROTEIN-KINASE-C | CYTOSOLIC PHOSPHOLIPASE A | membrane | calcium | signaling | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | subcellular localization | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | lipid | PLASMA-MEMBRANE | PHORBOL ESTER BINDING |