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Journal Article
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2012, Volume 18, Issue 4, pp. 600 - 604
Inflammatory bowel diseases (IBDs) are chronic relapsing and remitting conditions associated with long-term gut dysfunction resulting from alterations to the... 
MEDICINE, RESEARCH & EXPERIMENTAL | STIMULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNERVATION | RELEASE | CELL BIOLOGY | RECOVERY | INHIBITION | P2X RECEPTORS | MYENTERIC NEURONS | GLIA | ATP | MOTILITY | Myenteric Plexus - pathology | Calcium - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Gastrointestinal Motility - drug effects | Colitis - pathology | Male | Glial Fibrillary Acidic Protein - metabolism | Cytoskeletal Proteins - deficiency | Adenosine Triphosphate - pharmacology | Dose-Response Relationship, Drug | Caspases - metabolism | Time Factors | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Cytoskeletal Proteins - metabolism | Neurons - metabolism | Cell Death - drug effects | Dinitrofluorobenzene - analogs & derivatives | Neurons - drug effects | Disease Models, Animal | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Gastrointestinal Motility - genetics | Phosphodiesterase Inhibitors - pharmacology | Purinergic P2X Receptor Agonists - pharmacology | Adenosine Triphosphate - analogs & derivatives | Connexins - metabolism | Mice, Knockout | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Apoptosis Regulatory Proteins | Dinitrofluorobenzene - pharmacology | Analysis of Variance | Cell Death - physiology | Signal Transduction - drug effects | CARD Signaling Adaptor Proteins | Nitric Oxide Synthase Type I - metabolism | Receptors, Purinergic P2X7 - metabolism | Mice | Neural receptors | Neurons | Physiological aspects | Development and progression | Genetic aspects | Research | Colitis | Inflammatory bowel disease | Nervous system | Gene expression | Apoptosis | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2004, Volume 279, Issue 7, pp. 5821 - 5828
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, pp. e72607 - e72607
Pituitary adenylate cyclase activating peptide (PACAP) belongs to the secretin/glucagon/vasoactive intestinal peptide (VIP) family. Its action can be mediated... 
3T3-L1 ADIPOCYTES | CYCLIC-AMP | VASOACTIVE-INTESTINAL-PEPTIDE | RECEPTOR-GAMMA | MULTIDISCIPLINARY SCIENCES | INSULIN-SECRETION | GENE-EXPRESSION | POLYPEPTIDE PACAP | ADIPOCYTE DIFFERENTIATION | PPAR-GAMMA | C/EBP DELTA | CCAAT-Enhancer-Binding Proteins - metabolism | Insulin - physiology | CCAAT-Enhancer-Binding Protein-beta - genetics | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - antagonists & inhibitors | Phosphodiesterase Inhibitors - pharmacology | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Pituitary Adenylate Cyclase-Activating Polypeptide - physiology | 3T3-L1 Cells | 1-Methyl-3-isobutylxanthine - pharmacology | CCAAT-Enhancer-Binding Protein-beta - metabolism | MAP Kinase Signaling System | Animals | Dexamethasone - pharmacology | Glucocorticoids - pharmacology | Antigens, Differentiation - metabolism | Mice | CCAAT-Enhancer-Binding Proteins - genetics | Cyclic AMP - metabolism | Adipogenesis | Cyclic adenylic acid | Dexamethasone | Peptides | Protein binding | Phosphorylation | Transcription factors | PAC1 protein | Glucagon | Laboratories | Secretin | Activation | Biochemistry | Adipocytes | Kinases | Proteins | Signal transduction | Receptors | Intestine | Vasoactive agents | Rodents | Penicillin | Cell cycle | Pituitary adenylate cyclase-activating polypeptide receptors | Polypeptides | Extracellular signal-regulated kinase | Cyclic AMP | MAP kinase | Triglycerides | Metabolism | Gene expression | Insulin | Pituitary adenylate cyclase-activating polypeptide | Signaling | Hypotheses | Vasoactive intestinal peptide | Affinity | Diabetes | Index Medicus
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 03/2014, Volume 111, Issue 3, pp. 491 - 507
Platelet activation is relevant to a variety of acute thrombotic events. We sought to examine adenosine 5’-monophosphate (AMP) mechanisms of action in... 
A2A receptor | Platelets | adenosine 5’-monophosphate | PDE inhibition | Antithrombotic | Platelets and Blood Cells | Adenosine 5'-monophosphate | PROTEIN-KINASE-A | adenosine 5 '-monophosphate | P-SELECTIN EXPRESSION | A(2A) receptor | ATHEROSCLEROSIS | RECEPTOR | SOLANUM-LYCOPERSICON | antithrombotic | INHIBITION | ENDOTHELIUM | INFLAMMATION | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | AGGREGATION | Thrombosis - chemically induced | P-Selectin - metabolism | Stereoisomerism | Humans | Blood Platelets - physiology | Molecular Targeted Therapy | Photochemical Processes | Lectins, C-Type - metabolism | CD40 Ligand - metabolism | Adenosine A2 Receptor Agonists - pharmacology | Platelet Glycoprotein GPIIb-IIIa Complex - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Thrombosis - blood | Blood Platelets - drug effects | Lasers - utilization | Platelet Glycoprotein GPIIb-IIIa Complex - genetics | Mesenteric Veins - drug effects | Crotalid Venoms - metabolism | Disease Models, Animal | Peptide Fragments - metabolism | Triazines - pharmacology | Adenosine Monophosphate - metabolism | Cells, Cultured | Receptor, Adenosine A2A - metabolism | P-Selectin - genetics | Triazoles - pharmacology | Mesenteric Veins - radiation effects | Animals | Adenosine Monophosphate - analogs & derivatives | Rose Bengal - administration & dosage | Mice | Platelet Activation - drug effects | Thrombosis - drug therapy | Mesenteric Veins - physiology
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 1/2004, Volume 164, Issue 1, pp. 123 - 131
Amyloid-β peptide (Aβ) accumulation in senile plaques, a pathological hallmark of Alzheimer's disease (AD), has been implicated in neuronal degeneration. We... 
Oxidative stress | Cell death | Neurons | Ceramides | Lipids | Cultured cells | Cytotoxicity | Amyloids | Alzheimers disease | Apoptosis | Alzheimer's disease | White matter | cell death | DAUNORUBICIN-INDUCED APOPTOSIS | ALZHEIMERS-DISEASE | apoptosis | PC12 CELL-DEATH | INITIATE APOPTOSIS | CELL BIOLOGY | white matter | TUMOR-NECROSIS-FACTOR | GLUTATHIONE DEPLETION | IONIZING-RADIATION | IONIZATION MASS-SPECTROMETRY | NF-KAPPA-B | oxidative stress | Ethanolamines - pharmacology | Oligodendroglia - metabolism | Glutathione - metabolism | Amyloid beta-Peptides - pharmacology | Oxidative Stress - physiology | Nerve Degeneration - physiopathology | Spheroids, Cellular - cytology | Nerve Degeneration - metabolism | Oligodendroglia - drug effects | Sphingomyelin Phosphodiesterase - metabolism | Up-Regulation - physiology | Amyloid beta-Peptides - metabolism | Cell Death - drug effects | Oligodendroglia - cytology | Endocannabinoids | Alzheimer Disease - physiopathology | Ceramides - metabolism | Cells, Cultured | Oleic Acids | Rats | Ceramides - pharmacology | Up-Regulation - drug effects | Animals | Cell Death - physiology | Alzheimer Disease - metabolism | Signal Transduction - physiology | Sphingomyelins - pharmacology | Oxidative Stress - drug effects | Oxidation | Cellular biology | Toxicity | Index Medicus | Alzheimer's disease; apoptosis; cell death; oxidative stress; white matter
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2013, Volume 191, Issue 4, pp. 1744 - 1752
Journal Article