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Journal Article
Molecular Cell, ISSN 1097-2765, 03/2017, Volume 65, Issue 5, pp. 917 - 931.e6
Autophagy is crucial for maintaining cell homeostasis. However, the precise mechanism underlying autophagy initiation remains to be defined. Here, we... 
ARD1 | autophagy | tumor | PGK1 | mTOR | Beclin1 | VPS34 | BREAST-CANCER | NUCLEOTIDE SYNTHESIS | METABOLISM | SIGNALING PATHWAY | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHATIDYLINOSITOL 3-KINASE COMPLEXES | GROWTH | TUMOR-CELLS | BETA-CATENIN | TUMORIGENESIS | CELL BIOLOGY | Glioblastoma - enzymology | Glutamine - deficiency | Phosphorylation | Cell Proliferation | TOR Serine-Threonine Kinases - metabolism | Humans | Autophagosomes - enzymology | Brain Neoplasms - pathology | Autophagy | Tumor Hypoxia | TOR Serine-Threonine Kinases - genetics | Transfection | Glioblastoma - genetics | RNA Interference | Time Factors | HEK293 Cells | Female | Acetylation | Phosphoglycerate Kinase - genetics | Brain Neoplasms - enzymology | Signal Transduction | N-Terminal Acetyltransferase A - genetics | Brain Neoplasms - genetics | Class III Phosphatidylinositol 3-Kinases - metabolism | Tumor Burden | Autophagosomes - pathology | Animals | N-Terminal Acetyltransferase A - metabolism | Class III Phosphatidylinositol 3-Kinases - genetics | Mice, Nude | Glioblastoma - pathology | Beclin-1 - genetics | Cell Line, Tumor | N-Terminal Acetyltransferase E - genetics | Protein Binding | Beclin-1 - metabolism | N-Terminal Acetyltransferase E - metabolism | Phosphoglycerate Kinase - metabolism | Enzymes | Medical colleges | Gliomas | Pancreatic cancer | Brain tumors | Physiological aspects | Phospholipids | Protein kinases | Glutamine | Index Medicus
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2018, Volume 72, Issue 4, pp. 650 - 660.e8
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2016, Volume 61, Issue 5, pp. 705 - 719
It is unclear how the Warburg effect that exemplifies enhanced glycolysis in the cytosol is coordinated with suppressed mitochondrial pyruvate metabolism. We... 
hypoxia | K-Ras | PDH | mitochondria | glycolysis | PGK1 | B-Raf | tumorigenesis | PDHK1 | phosphorylation | EGFR | Mitochondria | Phosphorylation | Glycolysis | Hypoxia | Tumorigenesis | PYRUVATE-DEHYDROGENASE KINASE | HISTONE H3 | PKM2 | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | HYPOXIA | CANCER | PROMOTES | HUMAN PHOSPHOGLYCERATE KINASE | GENE-TRANSCRIPTION | CELL BIOLOGY | Mitochondria - enzymology | Receptor, Epidermal Growth Factor - genetics | Glioblastoma - enzymology | Cell Proliferation | Prognosis | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Pyruvate Dehydrogenase Complex - genetics | Cell Hypoxia | Receptor, Epidermal Growth Factor - metabolism | Transfection | Glioblastoma - genetics | RNA Interference | Time Factors | Female | Peptidylprolyl Isomerase - metabolism | Peptidylprolyl Isomerase - genetics | Phosphoglycerate Kinase - genetics | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Pyruvate Dehydrogenase Complex - metabolism | Signal Transduction | Protein-Serine-Threonine Kinases - genetics | Rats | NIMA-Interacting Peptidylprolyl Isomerase | Mitochondria - pathology | Citric Acid Cycle | Protein Transport | Animals | Mice, Nude | Proto-Oncogene Proteins B-raf - genetics | Glioblastoma - pathology | Cell Line, Tumor | Protein Binding | Enzyme Activation | Mutation | Phosphoglycerate Kinase - metabolism | Lactates | Glucose metabolism | Gliomas | Isomerization | Mitochondrial DNA | Protein kinases | Cells | Medical colleges | Brain tumors | Index Medicus
Journal Article
Molecules, ISSN 1420-3049, 06/2017, Volume 22, Issue 6, p. 1029
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2014, Volume 289, Issue 43, pp. 30012 - 30024
Journal Article
AIDS Research and Human Retroviruses, ISSN 0889-2229, 05/2018, Volume 34, Issue 5, pp. 421 - 429
Journal Article