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JOURNAL OF CELLULAR BIOCHEMISTRY, ISSN 0730-2312, 04/2019, Volume 120, Issue 4, pp. 5062 - 5071
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 04/2019, Volume 120, Issue 4, p. 5062
Mycobacterium tuberculosis (Mtb) infects millions of people each year. These bacilli can survive inside macrophages. To favor their survival, pathogen alters... 
Nitric oxide | Cellular signal transduction | Phospholipases
Journal Article
by Liu, YQ and Liu, TY and Zhao, J and He, TT and Chen, H and Wang, JQ and Zhang, WM and Ma, WR and Fan, YP and Song, XP
JOURNAL OF PHARMACY AND PHARMACOLOGY, ISSN 0022-3573, 05/2019, Volume 71, Issue 5, pp. 878 - 886
Objectives The drawback of bleeding caused by chronic antiplatelet therapy is persecuting patients with thrombotic diseases severely. Based on the... 
phospholipase C gamma 2 | notoginsenoside Ft1 | SECONDARY PREVENTION | ANTIPLATELET | Panax notoginseng | ADHESION | thrombosis | PROTEASE-ACTIVATED RECEPTORS | SAPONINS | PATHWAY | haemostasis | PANAX-NOTOGINSENG | PHARMACOLOGY & PHARMACY | SHAPE CHANGE | PLATELET ACTIVATION
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 05/2019, Volume 71, Issue 5, p. 878
The drawback of bleeding caused by chronic antiplatelet therapy is persecuting patients with thrombotic diseases severely. Based on the dual-directional... 
Thrombin | Phospholipases
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 12/2014, Volume 39, Issue 12, p. 603
* New evidence for disease-linked mutations in phospholipase C[gamma] (PLC[gamma]). * The molecular mechanism of dysfunction involves impact on autoinhibition. 
Phospholipases | Cancer
Journal Article
Journal Article
Experimental Dermatology, ISSN 0906-6705, 09/2019, Volume 28, Issue 9, p. 1051
Differentiation and proliferation of keratinocyte are controlled by various signalling pathways. The epidermal growth factor receptor (EGFR) is known to be an... 
Epidermal growth factor | Contact dermatitis | Analysis | Homeostasis | Skin | Phospholipases
Journal Article
EXPERIMENTAL DERMATOLOGY, ISSN 0906-6705, 09/2019, Volume 28, Issue 9, pp. 1051 - 1057
Differentiation and proliferation of keratinocyte are controlled by various signalling pathways. The epidermal growth factor receptor (EGFR) is known to be an... 
phospholipase C | SYSTEM | OXIDATIVE STRESS | ACTIVATION | sebaceous gland | irritant contact dermatitis | SKIN BARRIER | MICE LACKING | KERATINOCYTE MIGRATION | DERMATOLOGY | GROWTH-FACTOR RECEPTOR | keratinocyte | DIFFERENTIATION | EXPRESSION
Journal Article
by Fu, GP and Yu, M and Chen, YH and Zheng, YW and Zhu, W and Newman, DK and Wang, DM and Wen, RR
EUROPEAN JOURNAL OF IMMUNOLOGY, ISSN 0014-2980, 01/2017, Volume 47, Issue 1, pp. 74 - 83
Pre-T cell receptor (TCR) signaling is required for pre-T cell survival, proliferation, and differentiation from the CD4 and CD8 double negative (DN) to the... 
THYMOCYTE DEVELOPMENT | ACTIVATION | Pre-TCR | ADAPTER PROTEIN SLP-76 | MOUSE | RECEPTOR | PROFOUND BLOCK | IMMUNOLOGY | T-cell development | MICE LACKING | Signal transduction | Phospholipase C gamma 1 | Pre-T cell | SELECTION | TYROSINE KINASE SUBSTRATE | LAT
Journal Article
CELLULAR SIGNALLING, ISSN 0898-6568, 09/2016, Volume 28, Issue 9, pp. 1237 - 1251
Deletions in the gene encoding signal-transducing inositol phospholipid-specific phospholipase C-gamma(2) (PLC gamma(2)) are associated with the novel human... 
B-CELL RECEPTOR | C-GAMMA ISOZYMES | lnositol phospholipid | CA2+ ENTRY | MAST-CELLS | Cold temperature sensitivity | Rac2 GTPase | COMMON VARIABLE IMMUNODEFICIENCY | SIGNALING COMPLEX | CELL BIOLOGY | Autoinhibition | GAIN-OF-FUNCTION | Split PH domain | PLECKSTRIN HOMOLOGY DOMAIN | Phospholipase C-gamma | FUNCTION MUTATION | PHOSPHORYLATION-INDUCED ACTIVATION
Journal Article
by Kim, YS and Ok, CY and Park, JS and Lee, HY and Bae, YS
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 01/2017, Volume 482, Issue 4, pp. 1025 - 1029
Foreign body giant cell (FBGC) formation is associated with the inflammatory response following material implantation. However, the intracellular signaling... 
DC-STAMP | Phospholipase C gamma 1 | ACTIVATION | OSTEOCLASTS | FUSION | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Foreign body giant cell | Fusogenic gene | C ISOZYMES | BIOMATERIALS | RUNX1
Journal Article
eLife, ISSN 2050-084X, 2015, Volume 4, Issue 4, pp. 1 - 31
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2017, Volume 482, Issue 4, p. 1025
Foreign body giant cell (FBGC) formation is associated with the inflammatory response following material implantation. However, the intracellular signaling... 
Cathepsins | Enzymes | Medical colleges | Phospholipases | Macrophages
Journal Article
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, ISSN 0031-6768, 03/2009, Volume 457, Issue 5, pp. 1173 - 1185
Platelet activation at sites of vascular injury is triggered through different signaling pathways leading to activation of phospholipase (PL) C beta or PLC... 
GLYCOPROTEIN-VI | PHYSIOLOGY | COLLAGEN | PROTEIN | INTEGRIN | KINASE | ARTERIAL THROMBOSIS | IP3 | Phospholipase C | Ca2+ mobilization | IN-VIVO | RHO GTPASES | G-protein | COUPLED RECEPTORS | MICE | Rac1 | Platelets
Journal Article
by Liu, YQ and Liu, TY and Ding, K and Liu, ZY and Li, YY and He, TT and Zhang, WM and Fan, YP and Ma, WR and Cui, L and Song, XP
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 11/2018, Volume 9
Scope: Bleeding, the main drawback of clinically used chemical anti-thrombotic drug is resulted from the unidirectional suppression of platelet activity.... 
phospholipase C gamma 2 | antiplatelet effect | APOPTOSIS | Notoginsenoside Fc | platelet aggregation | Panax notoginseng | ADHESION | thrombosis | PROTEASE-ACTIVATED RECEPTORS | PATHWAY | SAPONINS | PANAX-NOTOGINSENG | PHARMACOLOGY & PHARMACY | PLATELET ACTIVATION | INHIBITOR | CORONARY-ARTERY-DISEASE
Journal Article
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