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Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, p. 12702
Metabolic pathways are reprogrammed in cancer to support cell survival. Here, we report that T-cell acute lymphoblastic leukemia (T-ALL) cells are... 
PHOSPHOLIPASE C-GAMMA-1 | INHIBITION | METABOLISM | PHOSPHORYLATION | PROTEIN-KINASE | MEMBRANE | MULTIDISCIPLINARY SCIENCES | FRIEND-CELLS | SIGNALS | THERAPEUTIC TARGETS
Journal Article
by Lu, YY and Li, XD and Zhou, HD and Shao, S and He, S and Hong, MN and Liu, JC and Xu, YL and Wu, YJ and Zhu, DL and Wang, JG and Gao, PJ
FASEB JOURNAL, ISSN 0892-6638, 05/2019, Volume 33, Issue 5, pp. 6254 - 6268
Kruppel-like factor (KLF) 15 has emerged as a critical regulator of fibrosis in cardiovascular diseases. However, the precise role that KLF15 and its... 
PHOSPHOLIPASE C-GAMMA-1 | MIGRATION | CONTRIBUTE | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | macrophage | vascular remodeling | KLF15 | Ang II | FIBROBLASTS | CELL BIOLOGY | adenovirus | DISEASE | BIOLOGY | DIFFERENTIATION | EXPRESSION
Journal Article
Journal of neurophysiology, ISSN 0022-3077, 02/2019, Volume 121, Issue 2, pp. 609 - 619
Hippocampal mossy fiber axons simultaneously activate CA3 pyramidal cells and stratum lucidum interneurons (SLINs). the latter providing feedforward inhibition... 
interneuron | TrkB | synaptic plasticity | hippocampus | BDNF | PHOSPHOLIPASE C-GAMMA-1 | LOCALIZATION | PHYSIOLOGY | SYNAPTIC-TRANSMISSION | IDENTIFICATION | NEUROSCIENCES | ZINC | LONG-TERM DEPRESSION | FEEDFORWARD INHIBITION | BRAIN | PLASTICITY
Journal Article
Oncogene, ISSN 0950-9232, 04/2014, Volume 33, Issue 16, pp. 2123 - 2133
The interactions between cancer cells and their microenvironment are crucial for malignant progression, as they modulate invasion-related activities.... 
macrophages | cancer cell invasion | tumor microenvironment | gastric cancer | invasion-related signaling pathways | colon cancer | PHOSPHOLIPASE C-GAMMA-1 | METASTASIS | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INFILTRATION | CELL BIOLOGY | INVASIVENESS | TUMOR-CELL MIGRATION | ONCOLOGY | INFLAMMATION | GROWTH | GENETICS & HEREDITY | CARCINOMA | PROGRESSION
Journal Article
NATURE REVIEWS IMMUNOLOGY, ISSN 1474-1733, 04/2004, Volume 4, Issue 4, pp. 301 - 308
Twenty years of investigation have yielded a detailed view of the signalling machinery engaged by T-cell receptors (TCRs). Many of the fundamental insights... 
PHOSPHOLIPASE C-GAMMA-1 | CYTOPLASMIC FREE CALCIUM | SEVERE COMBINED IMMUNODEFICIENCY | SHORT-INTERFERING RNAS | PROTEIN-TYROSINE KINASE | IMMUNOLOGY | LYMPHOCYTE REGULATORY MOLECULES | NF-KAPPA-B | ANTIGEN RECEPTOR | MAMMALIAN-CELLS | 2-STIMULUS REQUIREMENT
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2015, Volume 27, Issue 4, pp. 533 - 546
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/1993, Volume 268, Issue 28, pp. 20845 - 20850
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 07/1991, Volume 88, Issue 13, pp. 5484 - 5488
Stimulation of the T-cell antigen receptor (TCR), which itself is not a protein-tyrosine kinase (PTK), activates a PTK and phospholipase C (PLC). Using the... 
PHOSPHATIDYL-INOSITOL PATHWAY | STIMULATION | TYROSINE KINASE | MULTIDISCIPLINARY SCIENCES | INCREASES | PHOSPHATIDYLINOSITOL | PROLIFERATION | PDGF RECEPTOR | CD4 | CALCIUM | T-CELL ACTIVATION | PROTEIN KINASE P56LCK | SIGNAL TRANSDUCTION | ASSOCIATION
Journal Article
BLOOD, ISSN 0006-4971, 02/2008, Volume 111, Issue 4, pp. 2354 - 2363
Herbs have successfully been used in traditional Chinese medicine for centuries. However, their curative mechanisms remain largely unknown. In this study, we... 
PHOSPHOLIPASE C-GAMMA-1 | HEPATOCELLULAR-CARCINOMA CELLS | MITOCHONDRIAL PERMEABILITY TRANSITION | CYCLOPHILIN-D | CA2+ MOBILIZATION | GENE-EXPRESSION | SCUTELLARIA-BAICALENSIS GEORGI | ENDOPLASMIC-RETICULUM | HYDROGEN-PEROXIDE | ANTICANCER DRUGS | HEMATOLOGY
Journal Article
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