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American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2017, Volume 312, Issue 6, pp. C765 - C774
Journal Article
Blood, ISSN 0006-4971, 03/2010, Volume 115, Issue 10, pp. 2008 - 2013
During platelet activation, phosphoinositide 3-kinases (PI3Ks) produce lipid second messengers participating in the regulation of functional responses. Here,... 
PHOSPHOLIPASE C-GAMMA-2 | STIMULATION | PATHWAY | ITAM | MEDIATED ACTIVATION | HEMATOLOGY | PEPTIDE
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 11/2018, Volume 315, Issue 5, pp. C687 - C698
Most kidney stones (KS) are composed of calcium oxalate, and small increases in urine oxalate affect the stone risk. Intestinal oxalate secretion mediated by... 
A | adenosine receptor | PKC | Inflammation | Intestinal oxalate transport | SLC26A6 | Phospholipase C
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 12/2019, Volume 1198
Phospholipase C epsilon gene (PLCE1) is encoded the 1-phosphatidylinositol 4,5- bisphosphate phosphodiesterase ɛ-1 protein. This protein is characterized by... 
Phospholipase C epsilon gene | Molecular dynamic simulations | Molecular docking
Journal Article
Genes and Development, ISSN 0890-9369, 11/2007, Volume 21, Issue 21, pp. 2731 - 2746
Journal Article
Journal of Cell Science, ISSN 0021-9533, 08/2011, Volume 124, Issue 15, pp. 2582 - 2590
Journal Article
Neuron, ISSN 0896-6273, 08/2015, Volume 87, Issue 3, pp. 549 - 562
Major depressive disorder is among the most commonly diagnosed disabling mental diseases. Several non-pharmacological treatments of depression upregulate... 
HIPPOCAMPUS | ACTIVATION | STIMULATION | PHOSPHOLIPASE-C | MECHANISMS | PYRAMIDAL CELL EXCITABILITY | EXPRESSION | NEUROSCIENCES | MICE LACKING | BRAIN | ECONOMIC BURDEN
Journal Article
Acta virologica, ISSN 0001-723X, 2019, Volume 63, Issue 1, pp. 117 - 120
The phospholipase C (PLC) is a family of kinases that hydrolyze phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] to generate two second messengers, inositol... 
phospholipase C | U73122 | VIROLOGY | PLC gamma-1 | PRRSV
Journal Article
Journal of Cell Science, ISSN 0021-9533, 05/2004, Volume 117, Issue 12, pp. 2513 - 2521
Journal Article
Bioelectrochemistry, ISSN 1567-5394, 12/2014, Volume 100, pp. 80 - 87
The interaction between nsPEF-induced Ca release and nsPEF-induced phosphatidylinositol -bisphosphate (PIP ) hydrolysis is not well understood. To better... 
Electric pulse | PIP2 depletion | Nanopore | Calcium | Phospholipase C | depletion | PIP
Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 03/2014, Volume 85, Issue 3, pp. 492 - 509
The concepts of functional selectivity and ligand bias are becoming increasingly appreciated in modern drug discovery programs, necessitating more informed... 
INVERSE AGONISTS | BETA-ADRENERGIC BLOCKERS | BETA-2-ADRENERGIC RECEPTOR | CRYSTAL-STRUCTURE | HEART-FAILURE | PHOSPHOLIPASE-C | PROTEIN-COUPLED RECEPTORS | RESONANCE ENERGY-TRANSFER | FUNCTIONAL SELECTIVITY | PHARMACOLOGY & PHARMACY | PHARMACOLOGICAL AGONISM
Journal Article
Human Reproduction, ISSN 0268-1161, 11/2008, Volume 23, Issue 11, pp. 2513 - 2522
BACKGROUND Recent studies suggest that in mammals, oocyte activation at fertilization is triggered by a sperm-specific phospholipase C, PLCζ. We investigated... 
Oocyte activation | Capacitation | Phospholipase C zeta | Acrosome reaction | Sperm
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 08/2012, Volume 14, Issue 8, pp. 850 - U168
Activation of the TRPM8 ion channel in sensory nerve endings produces a sensation of pleasant coolness. Here we show that inflammatory mediators such as... 
ALPHA-SUBUNITS | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | PHOSPHORYLATION | MEMBRANE | G-PROTEINS | PHOSPHOLIPASE-C | RECEPTOR | MICE | TRPV1 | LIVING CELLS | CELL BIOLOGY
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2019, Volume 202, Issue 1, pp. 228 - 238
Current advances in combined antiretroviral therapy have rendered HIV infection a chronic, manageable disease; however, the problem of persistent immune... 
INTERFERON-ALPHA | ACTIVATION | VIRUS | CRACC | MONOCYTE SUBSET | EAT-2 | IMMUNOLOGY | CCR5 | EXPRESSION | PHOSPHOLIPASE C-GAMMA | CELL-DEATH
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 12/2004, Volume 287, Issue 6, pp. 1679 - 1687
The mechanism of phospholipase (PLC)-δ activation by G protein-coupled receptor agonists was examined in rabbit gastric smooth muscle. Ca2+ stimulated an... 
G protein | Phospholipase C
Journal Article
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