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phosphorylated histone h2ax (125) 125
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Journal Article
Current Protocols in Cytometry, ISSN 1934-9297, 06/2019, Volume 89, Issue 1, p. e55
This unit describes immunocytochemical detection of histone H2AX phosphorylated on Ser-139 (γH2AX) to reveal DNA damage, particularly when the damage involves... 
flow cytometry | phosphorylated histone | double-strand breaks | cell cycle | DNA damage | immunofluorescence
Journal Article
The EMBO Journal, ISSN 0261-4189, 04/2010, Volume 29, Issue 8, pp. 1446 - 1457
Chromatin acts as a key regulator of DNA‐related processes such as DNA damage repair. Although ChIP‐chip is a powerful technique to provide high‐resolution... 
DSB repair | transcription | γH2AX | ChIP‐chip | GH2AX | ChIP-chip | Transcription | RECOMBINATION | CHROMATIN-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACHINERY | CHROMOSOMES | CELL BIOLOGY | PHOSPHORYLATED HISTONE H2AX | REPAIR | gamma H2AX | ATM | EXPRESSION | PROGRESSION
Journal Article
Chromosoma, ISSN 0009-5915, 12/2009, Volume 118, Issue 6, pp. 683 - 692
Journal Article
DNA Repair, ISSN 1568-7864, 2006, Volume 5, Issue 5, pp. 534 - 543
Journal Article
BMC Cancer, ISSN 1471-2407, 01/2010, Volume 10, Issue 1, pp. 4 - 4
Background: Evidence suggests that tumor cells exposed to some DNA damaging agents are more likely to die if they retain microscopically visible gamma H2AX... 
PHOSPHORYLATED HISTONE H2AX | X-RAYS | ONCOLOGY | DOUBLE-STRAND BREAKS | RADIATION SENSITIVITY | MISMATCH REPAIR | TUMOR-CELLS | HOMOLOGOUS RECOMBINATION | IONIZING-RADIATION | DAMAGE | CANCER CELL-LINES
Journal Article
CELL CYCLE, ISSN 1538-4101, 12/2006, Volume 5, Issue 24, pp. 2909 - 2913
Current advances in cancer biology have identified major pathways involved in tumorigenesis. The association of DNA damage with premalignant stages of tumor... 
DNA damage | MARKERS | DOUBLE-STRAND BREAKS | cancer biomarker | CELL BIOLOGY | GENOMIC INSTABILITY | PHOSPHORYLATED HISTONE H2AX | REPAIR | EPIGENETICS | tumor progression | DNA-DAMAGE CHECKPOINT | genome instability | gamma H2AX | THERAPEUTIC TARGET | IN-VIVO | SENESCENCE
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 2006, Volume 21, Issue 2, pp. 201 - 214
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2009, Volume 15, Issue 10, pp. 3344 - 3353
Purpose: Is retention of gamma H2AX foci useful as a biomarker for predicting the response of xenograft tumors to cisplatin with X-ray? Is a similar approach... 
MICRONUCLEI | SURVIVAL | UTERINE CERVIX | CELLS | PHOSPHORYLATED HISTONE H2AX | ONCOLOGY | DOUBLE-STRAND BREAKS | CERVICAL-CANCER | RADIOTHERAPY | CYTOMETRY | RADIATION
Journal Article