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Organic Letters, ISSN 1523-7060, 08/2017, Volume 19, Issue 16, pp. 4383 - 4386
The first arylogous Michael reaction of 3-aryl phthalides has been developed. The reaction, promoted by catalytic amounts of KOH or K3PO4 and... 
3-ALKENYL PHTHALIDES | RHODIUM | ENANTIOSELECTIVE SYNTHESIS | ANNULATION | CHIRAL PHTHALIDES | NATURAL-PRODUCTS | ACCESS 3-ARYL | CHEMISTRY, ORGANIC | CYCLOPEPTOIDS | PHASE-TRANSFER CATALYSTS | DERIVATIVES
Journal Article
by Zhang, S and Li, LJ and Wang, HQ and Li, Q and Liu, WM and Xu, K and Zeng, CC
ORGANIC LETTERS, ISSN 1523-7060, 01/2018, Volume 20, Issue 1, pp. 252 - 255
A practical, electrochemical method is developed for the direct dehydrogenative lactonization of C(sp(2)/sp(3))-H bonds under external oxidant- and metal-free... 
FUNCTIONALIZATION | OXIDATION | PHTHALIDES | HETEROCYCLES | LACTONES | OXYGENATION | ARENES | CHEMISTRY, ORGANIC | C(SP)-H | CARBOXYLIC-ACIDS | BENZOIC-ACIDS
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 06/2018, Volume 83, Issue 12, pp. 6673 - 6680
The cycloisomerization of readily available 2-alkynylbenzoic acids 1 in ionic liquids (ILs) as recyclable reaction media has been studied under the catalytic... 
KETONES | PHTHALIDES | COMPLEX | INTRAMOLECULAR CYCLIZATION | CHEMISTRY, ORGANIC | TERMINAL ALKYNES | ISOCOUMARINS
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 05/2019, Volume 25, Issue 29, pp. 7039 - 7039
Crowned wedding: A highly diastereoselective arylogous Michael reaction of unactivated phthalides was achieved using catalytic amounts of KOH and 18‐crown‐6.... 
Michael addition | phthalides | density functional calculations | crown compounds | diastereoselectivity
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 09/2018, Volume 119, pp. 309 - 325
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 11/2012, Volume 354, Issue 16, pp. 2933 - 2938
Journal Article
by Zhu, YQ and Li, JX and Han, TF and He, JL and Zhu, K
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, ISSN 1434-193X, 01/2017, Issue 4, pp. 806 - 811
Under rhodium(III)-catalyzed conditions, a broad range of benzoic acids reacted with acrylates successfully to provide phthalides through the direct... 
SYSTEM | Oxygen heterocycles | 3-SUBSTITUTED PHTHALIDES | CHEMISTRY, ORGANIC | INTERNAL ALKYNES | C-H activation | Rhodium | SOLE OXIDANT | Homogeneous catalysis | H BOND ALKENYLATIONS | Phthalides | OXIDATIVE CYCLIZATION | DERIVATIVES | Solvent effects | C-H | CARBOXYLIC-ACIDS | BENZOIC-ACIDS
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2018, Volume 57, Issue 40, pp. 13140 - 13144
Journal Article
Tetrahedron, ISSN 0040-4020, 12/2015, Volume 71, Issue 49, pp. 9264 - 9270
For the preparation of 3-alkoxyphthalides from phthalaldehydes and alcohols, a cyclization reaction in the presence of a rhodium(III) catalyst and copper(II)... 
Phthalides | Rhodium | Cyclization | Phthalaldehydes | C–C bond formation | C-C bond formation | ISOINDOLINONES | ACIDS | CATALYZED SYNTHESIS | COMPLEXES | 3-SUBSTITUTED PHTHALIDES | ESTERIFICATION | CHEMISTRY, ORGANIC | ALDEHYDES | ALKYNES | C-H ACTIVATION | LACTONES
Journal Article
by Liu, S and Chen, K and Hao, WJ and Tu, XC and Tu, SJ and Jiang, B
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 02/2019, Volume 84, Issue 4, pp. 1964 - 1971
A new palladium(II)-catalyzed cyclization-radical addition cascade enables the direct construction of 1,3-dimethylene-substituted isobenzofuran derivatives... 
PHOTOSENSITIZER-FREE | FUNCTIONALIZATION | 1,7-ENYNES | PHTHALIDES | DIAZONIUM SALTS | SULFUR-DIOXIDE | 1,3-DIHYDROISOBENZOFURANS | CHEMISTRY, ORGANIC | STEREOSELECTIVE-SYNTHESIS | CYCLIZATION | DOMINO
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2014, Volume 55, Issue 5, pp. 982 - 984
Total synthesis of (±)-herbaric acid and (±)-(4-methoxybenzyl)-5,7-dimethoxyphthalide, two natural phthalide products, was achieved in 8 steps and 5 steps,... 
Phthalides | Cyclisation | Copper catalysis | Total synthesis | GAMMA | ROUTE | ACID | CHEMISTRY, ORGANIC | CHIRAL C--FUNCTIONALIZED PHTHALIDES | FRULLANIA-FALCILOBA | ISOCOUMARINS | DERIVATIVES | Tetrahedrons | Synthesis (chemistry) | Cross coupling | Terminals | Derivatives | Alkynes
Journal Article
ORGANIC LETTERS, ISSN 1523-7060, 09/2019, Volume 21, Issue 18, pp. 7460 - 7465
Several phthalides were semisynthesized, including a 3,8-dihydrodiligustilide with progesterone-like activity, previously isolated from Ligusticum chuanxiong,... 
ACTIVATION | PHTHALIDES | THERAPY | CHEMISTRY, ORGANIC | ROOTS | RISK | PROGESTERONE-RECEPTOR | LIGUSTICUM-PORTERI
Journal Article
Organic Letters, ISSN 1523-7060, 10/2016, Volume 18, Issue 20, pp. 5220 - 5223
Disclosed herein an overall methodology constitutes an equivalent to the long sought after enantioselective intramolecular oxa-Michael (IOM) reaction of... 
ALKENES | ENANTIOSELECTIVE SYNTHESIS | REGIOSPECIFIC SYNTHESIS | 3-SUBSTITUTED PHTHALIDES | CHEMISTRY, ORGANIC | ALDEHYDES | ALKOXYBORONATE | CYCLIZATION | DIHYDROISOCOUMARIN | CYCLOHEXADIENONES | DESYMMETRIZATION
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 12/2018, Volume 24, Issue 67, pp. 17691 - 17696
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 11/2019, Volume 2019, Issue 41, pp. 6961 - 6967
A new, simple, and rapid photochemical reaction of o‐phthalaldehyde with C60 has been disclosed. This reaction afforded exclusively the unanticipated... 
Phthalides | Radical reactions | o–Phthalaldehyde | Fullerene C60 | Photochemistry
Journal Article