X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry, organic (22) 22
index medicus (22) 22
phthalimidine (20) 20
derivatives (15) 15
animals (13) 13
phthalimidines (12) 12
aids/hiv (11) 11
thalidomide - analogs & derivatives (11) 11
2phthalimidine (10) 10
em-12 (9) 9
polymer science (8) 8
isoindolinones (7) 7
amines (6) 6
chemistry (6) 6
chemistry, multidisciplinary (6) 6
enantiomers (6) 6
female (6) 6
molecular structure (6) 6
cyclization (5) 5
em 12 (5) 5
polyimides (5) 5
polymers (5) 5
polys (5) 5
rats (5) 5
stereoisomerism (5) 5
thalidomide (5) 5
activation (4) 4
alkylation (4) 4
analog (4) 4
analogs (4) 4
callithrix (4) 4
chemistry, medicinal (4) 4
gas permeability (4) 4
humans (4) 4
inhibitors (4) 4
kinetics (4) 4
o-phthalaldehyde (4) 4
synthesis (4) 4
teratologie (4) 4
2--phthalimidine (3) 3
analysis (3) 3
callithrix jacchus (3) 3
chemistry/food science, general (3) 3
em12 (3) 3
fibrinogen receptor antagonists (3) 3
hydrogen-ion concentration (3) 3
inorganic chemistry (3) 3
integrins (3) 3
isoindoles (3) 3
lactams (3) 3
letter (3) 3
male (3) 3
marmoset (3) 3
membranes (3) 3
mice (3) 3
models, chemical (3) 3
organic chemistry (3) 3
permeability (3) 3
pharmacology & pharmacy (3) 3
phthalimidine moiety (3) 3
platelet aggregation (3) 3
pregnancy (3) 3
receptor (3) 3
rgd mimetics (3) 3
structure-activity relationship (3) 3
structure-property correlationship (3) 3
structure–property correlationship (3) 3
supidimide (3) 3
temperature (3) 3
thalidomide - pharmacokinetics (3) 3
thalidomide - pharmacology (3) 3
thalidomide - toxicity (3) 3
thalidomide derivative (3) 3
zugfestigkeit (3) 3
1,2,3-1h-benzotriazole (2) 2
2-mercaptoethanol (2) 2
26581-81-7 (2) 2
acid (2) 2
adhesion receptors (2) 2
alkaloids (2) 2
alphabeta (2) 2
alternaria-porri (2) 2
antibodies, monoclonal (2) 2
antifungal agents - chemical synthesis (2) 2
aspergillus duricaulis (2) 2
asymmetric-synthesis (2) 2
auxiliaries (2) 2
biochemistry & molecular biology (2) 2
biosynthesis (2) 2
carbon-dioxide (2) 2
catalysis (2) 2
cell surface receptor (2) 2
chemistry, analytical (2) 2
condensation (2) 2
condensation reaction (2) 2
cycloaddition (2) 2
design (2) 2
disease models, animal (2) 2
down-regulation - drug effects (2) 2
drug design (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Tetrahedron, ISSN 0040-4020, 01/2018, Volume 74, Issue 2, pp. 224 - 239
One approach for the synthesis of isoindolinones, a privileged bioactive heterocyclic core structure, involves a condensation reaction of phthaldialdehydes... 
o-phthaldialdehyde | Condensation reaction | Mechanistic understanding | Regioselectivity | ISOINDOLINONES | ISOQUINOLINES | ANALOGS | AMINES | CHEMISTRY, ORGANIC | PHTHALIMIDINE FORMATION | PHTHALALDEHYDE | DERIVATIVES
Journal Article
HETEROCYCLES, ISSN 0385-5414, 04/2019, Volume 99, Issue 1, pp. 222 - 237
Direct condensation between phthalide and a primary amine in the presence of Lewis acid was achieved for the first time in organic solvent-diluted reaction... 
ISOINDOLINONES | DUAL SYNTHETIC AUXILIARIES | MECHANISM | 1,2,3-1H-BENZOTRIAZOLE | CHEMISTRY, ORGANIC | 2-MERCAPTOETHANOL | CONDITION PHTHALIMIDINE SYNTHESIS
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2013, Volume 21, Issue 15, pp. 4646 - 4661
A series of novel RGD mimetics containing phthalimidine fragment was designed and synthesized. Their antiaggregative activity determined by Born’s method was... 
Fibrinogen receptor antagonists | αIIbβ3 | RGD mimetics | Platelet aggregation | Phthalimidine
Journal Article
Tetrahedron, ISSN 0040-4020, 10/2016, Volume 72, Issue 40, pp. 6136 - 6141
Click analogues of thalidomide were prepared from 3-azidoglutarimide and a diverse array of arylacetylenes and -ethynyl/ -propargyl phthalimide derivatives.... 
Teratogenesis | Angiogenesis | TNF-α | EM-12 | Multiple myeloma | Thalidomide | Cancer | MULTIPLE-MYELOMA | ACTIVATION | TNF-alpha | ENANTIOMERS | CHEMISTRY, ORGANIC | PHTHALIMIDINE | CYCLOADDITION | ANTIANGIOGENIC ACTIVITY | METABOLISM | CHEMISTRY | DERIVATIVES | Triazoles | Synthesis | Sodium | Phthalimides | Reagents | Coupling | Derivatives | Arrays
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 04/2014, Volume 55, Issue 14, pp. 2286 - 2289
A new synthetic method has been developed for the synthesis of 2,4,5-substituted isoindolinones by means of intramolecular inverse-electron demand Diels–Alder... 
Chloropyridazines | Isoindolinones | Diels–Alder cycloadditions | Phthalimidine | Inverse-electron demand cyclizations | Diels-Alder cycloadditions | STAUROSPORINE | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | DERIVATIVES | Pyridazines | Demand | Tetrahedrons | Synthesis (chemistry) | Cycloaddition
Journal Article
Letters in Organic Chemistry, ISSN 1570-1786, 03/2017, Volume 14, Issue 3, pp. 153 - 158
Background: We previously reported the 1:1 condensation reaction between o-phthalaldehyde and primary amine in the presence of 1,2,3-1H-benzotriazole and... 
Lewis acid | Catalytic | Phthalide | Direct condensation | InCl3 (Indium chloride) | Phthalimidine | direct condensation | AUXILIARIES | REDUCTION | lewis acid | 1,2,3-1H-BENZOTRIAZOLE | CHEMISTRY, ORGANIC | 2-MERCAPTOETHANOL | phthalide | phthalimidine | ZINC
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY, ISSN 0968-0896, 08/2013, Volume 21, Issue 15, pp. 4646 - 4661
A series of novel RGD mimetics containing phthalimidine fragment was designed and synthesized. Their antiaggregative activity determined by Born's method was... 
DESIGN | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | CRYSTAL-STRUCTURES | Platelet aggregation | Phthalimidine | ANTIPLATELET THERAPY | RGD mimetics | PLATELETS | Fibrinogen receptor antagonists | alpha(IIb)beta | AGGREGATION
Journal Article
Journal of Membrane Science, ISSN 0376-7388, 2010, Volume 350, Issue 1, pp. 53 - 61
Journal Article
Organic Letters, ISSN 1523-7060, 07/2011, Volume 13, Issue 13, pp. 3490 - 3493
A nickel(0) catalyst effectively mediates the cyclization of N-benzoyl aminals in the presence of a stoichiometric Lewis acid. This method enables preparation... 
SUBSTITUTION | ACTIVATION | ASYMMETRIC-SYNTHESIS | ONE-STEP SYNTHESIS | IMINES | BONDS | PALLADIUM-CATALYZED ARYLATION | PAGOCLONE | CHEMISTRY, ORGANIC | DERIVATIVES | PHTHALIMIDINES | Benzylamines - chemistry | Isoindoles - chemical synthesis | Molecular Structure | Catalysis | Cyclization | Nickel - chemistry | Index Medicus
Journal Article
European Polymer Journal, ISSN 0014-3057, 03/2014, Volume 52, Issue 1, pp. 207 - 217
This article describes the synthesis, characterization and gas transport properties of a series of new fluorinated poly(arylene ether)s (PAE)s, prepared from... 
Gas permeability | Dielectric constant | Cyclohexylidene moiety | Structure–property correlationship | Structure-property correlationship | MAIN-CHAIN | POLYMER SCIENCE | POLYSULFONES | POLYMER MEMBRANES | PHTHALIMIDINE MOIETY | SEPARATION | BACKBONE | CARBON-DIOXIDE | POLYIMIDES | PERMEATION
Journal Article
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 08/2006, Volume 71, Issue 16, pp. 5951 - 5958
A phosphine-free catalytic system [Pd(OAc)(2)-Cu(OAc)(2)-air] induced a substrate-specific carbonylation of amines in boiling toluene under CO gas (1 atm).... 
PHOTOCHEMICAL CARBONYLATION | C-H BOND | CARBON-MONOXIDE | SQUARE-PLANAR COMPLEXES | HIGH PRESSURE REACTION | CHEMISTRY, ORGANIC | CATALYTIC OXIDATIVE CARBONYLATION | YIELD SUBSTITUTED PHTHALIMIDINES | NOBLE-METAL COMPOUNDS | TERT-BUTYL PEROXIDE | ALPHA-KETO AMIDES
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 03/2014, Volume 51, Issue 2, pp. 357 - 362
This paper presents a dualistic behavior of 2‐substituted‐3‐hydroxyisoindolones in reactions with sec ‐butyllithium ( sec ‐BuLi). 2‐ tert... 
UBER ISOINDOLE | ALTERNARIA-PORRI | ALKYLATION | DIRECTED ORTHO-METALATION | SYNTHETIC STRATEGIES | TERTIARY AMIDE | CHEMISTRY, ORGANIC | INHIBITORS | DERIVATIVES | ORGANOLITHIUM | PHTHALIMIDINE
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1999, Volume 9, Issue 11, pp. 1625 - 1630
Thalidomide, (1), is a known inhibitor of TNF-α release in LPS stimulated human PBMC. Herein we describe the TNF-α inhibitory activity of amino substituted... 
Thalidomide - analogs & derivatives | Thalidomide - chemical synthesis | Models, Chemical | U937 Cells | Humans | Blood - drug effects | Inhibitory Concentration 50 | Structure-Activity Relationship | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | AIDS/HIV
Journal Article
Separation and Purification Technology, ISSN 1383-5866, 01/2013, Volume 103, pp. 222 - 229
Journal Article
Heterocycles, ISSN 0385-5414, 06/2004, Volume 63, Issue 6, pp. 1267 - 1271
The structure of the double Mannich condensation product from ophthalaldehyde and substituted aniline was proved to be iminoisoindoline, but not diimine, based... 
CHEMISTRY, ORGANIC | PHTHALIMIDINES
Journal Article
Journal of Polymer Science, Part A: Polymer Chemistry, ISSN 0887-624X, 1994, Volume 32, Issue 2, pp. 369 - 382
N-Phenyl-3,3-Bis[4-(p-aminophenoxy)phenyl]phthalimidine (II) was used as a monomer with various aromatic dicarboxylic acids and tetracarboxylic dianhydrides to... 
N‐phenyl‐3,3‐bis (4‐hydroxyphenyl) phthalimidine | polyamides | N‐phenyl‐3,3‐bis[4‐(p‐aminophenoxy)phenyl] phthalimidine | polyimides | POLYMER SCIENCE | N-PHENYL-3,3-BIS[4-(P-AMINOPHENOXY)PHENYL]PHTHALIMIDINE N-PHENYL-3,3-BIS(4-HYDROXYPHENYL)PHTHALIMIDINE | POLYAMIDES | POLYIMIDES
Journal Article
Journal of Applied Polymer Science, ISSN 0021-8995, 05/2009, Volume 112, Issue 3, pp. 1226 - 1233
Five new poly(arylene ether)s containing phthalimidine group in the main chain and pendent trifluoromethyl group have been prepared by the reaction of... 
Thermal properties | Mechanical properties | Phthalimidine | Poly(arylene ether)s | POLYMERS | POLYMER SCIENCE | thermal properties | TRIFLUOROMETHYL GROUPS | poly(arylene ether)s | phthalimidine | mechanical properties
Journal Article
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.